Sentences with phrase «transporter promoter»

Dopamine D4 receptor (D4DR) and serotonin transporter promoter (5 - HTTLPR) polymorphisms in the determination of the temperament in 2 - month - old infants

Serotonin transporter promoter gain - of - function genotypes are linked to obsessive — compulsive disorder

Higher 5 - HTT CpG methylation, but not sequence variation in the serotonin transporter promoter region, exacerbates the effects of early life stress on behavioral stress reactivity.

Associations of the serotonin transporter promoter polymorphim with aggressivity, attention deficit, and conduct disorder in an adoptee population

The association of the dopamine D4 receptor gene (DRD4) and the serotonin transporter promoter gene (5 - HTTLPR) with temperament in 12 - month - old infants

The serotonin transporter promoter variant (5 - HTTLPR), stress, and depression meta - analysis revisited: Evidence of genetic moderation

The serotonin transporter promoter insertion / deletion polymorphism (5HTTLPR) has been implicated in psychopathy.

Prenatal effects of selective serotonin reuptake inhibitors antidepressents, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age.

Family - based association study of the serotonin transporter promoter region polymorphism (5 - HTTLPR) in attention deficit hyperactivity disorder

Conclusion Children who manifest higher levels of shyness or have 1 or 2 copies of the short allele of the serotonin transporter promoter gene appear to have a different pattern of processing affective stimuli of interpersonal hostility.

To determine whether childhood shyness, or the serotonin transporter promoter polymorphism genotype, can predict participants» visual event - related potentials in response to expressions of children of similar ages.

Influence of the Serotonin Transporter Promoter Gene and Shyness on Children's Cerebral Responses to Facial Expressions.

Children who manifest higher levels of shyness or have 1 or 2 copies of the short allele of the serotonin transporter promoter gene appear to have a different pattern of processing affective stimuli of interpersonal hostility.

The serotonin transporter promoter variant (5 - HTTLPR), stress and depression meta - analysis revisited

Early family environment, current adversity, the serotonin transporter promoter polymorphism, and depressive symptomatology

Not exact matches

Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.

A functional polymorphism in the promoter region of the human serotonin transporter gene (SLC6A4) has been associated with several dimensions of neuroticism and psychopathology, especially anxiety traits, but the predictive value of this genotype against these complex behaviors has been inconsistent.

Although more studies are needed to confirm a genetic link between anxiety and the promoter and its associated serotonin transporter gene, this DNA «is one of the best prospects for a gene in anxiety - related behaviors that we have,» says David Goldman, a geneticist at the National Institute on Alcohol Abuse and Alcoholism in Rockville, Maryland.

Comparative analysis of length polymorphisms in the promoter region of the serotonin transporter gene (SLC6A4) in Cercopithecidae [abstract].

The short form of the serotonin transporter gene promoter does not explain autism, insists Dr. Cook, who heads a nationwide consortium of researchers looking for the genetic underpinnings of this disease, but it does appear to play a significant role, perhaps in concert with other abnormalities which we've not yet uncovered.

In the present study, we interrogated the role of this transporter in breast cancer by deleting Slc6a14 in mice and monitoring the consequences of this deletion in models of spontaneous breast cancer (Polyoma middle T oncogene - transgenic mouse and mouse mammary tumour virus promoter - Neu - transgenic mouse).

The present study suggests that this risk for depression is moderated by social supports and polymorphic variation of the VNTR in the promoter region of the serotonin transporter gene (5 - HTTLPR).

The s allele of 5 - HTTLPR contains an attenuated promoter segment and is associated with reduced transcription and functional capacity of the serotonin transporter relative to the l allele (18, 19).

In this study, measures of the quality and availability of social supports were found to moderate risk for depression associated with a history of maltreatment and the presence of the short (s) allele of the serotonin transporter gene promoter polymorphism (5 - HTTLPR).

We studied the well known functional polymorphism in the 5 ′ flanking regulatory (promoter) region of the gene (SLC6A4) coding for the serotonin transporter protein.

However, researchers at the University of California — Berkeley wanted to find out if there might a genetic component that could predict how couple interactions affect marital satisfaction.5 Specifically, the team decided to look at the 5 - HTTLPR polymorphism in the promoter region of the serotonin transporter gene.

This investigation examined the extent to which polymorphisms of the serotonin transporter linked promoter region (5 - HTTLPR) and the dopamine receptor D4 (DRD4) genes differentially influenced the development of attachment security and disorganization in maltreated and nonmaltreated infants at age 13 months, and the extent to which the efficacy of preventive interventions to promote attachment security were influenced by genetic variation.

Obsessive - compulsive disorder and the promoter region polymorphism (5 - HTTLPR) in the serotonin transporter gene (SLC6A4): a negative association study in the Afrikaner population

Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm

In relation to the association of infant attachment with a promoter polymorphism of the serotonin transporter gene, we have mentioned that gene expression may be affected by variation in the DNA sequence of the regulatory region of the gene.

Adults who had been categorized as behaviorally inhibited at the age of 2 years exhibited a higher amygdala activation in response to unknown vs familiar faces16 compared with adults who were uninhibited as children, consistent with the notion that novel or ambiguous environmental stimuli of potential biological relevance activate the amygdala.17 Turning to genes that can influence the neurobiological bases of the processing of emotions, 2 common alleles, the short (S) and the long (L), in a variable repeat sequence of the serotonin transporter (5 - HTT) promoter polymorphism (5 - HTTLPR) on human chromosome 17q11 have been differently associated with greater amygdala activity in response to angry or fearful faces18 in healthy adults.

Importantly, we have recently shown that differential DNA methylation of the serotonin transporter gene promoter (SLC6A4) in T cells and monocytes is associated with in vivo measures of human brain serotonin synthesis and childhood limited physical aggression in men [46].

Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic - hypothalamic - pituitary - adrenal axis regulation in monkeys.

Socioeconomic status mediates the genetic contribution of the dopamine receptor D4 and serotonin transporter linked promoter region repeat polymorphisms to externalization in preadolescence

Early life adversity and serotonin transporter gene variation interact to affect DNA methylation of the corticotropin - releasing factor gene promoter region in the adult rat brain