Not exact matches
Published in the journal Proceedings of the National Academy of Sciences, the team, led by Professors Claire Harris and Professor Paul Morgan, showed that when the «homing» agent was injected into mice immediately after
traumatic brain injury, it specifically targeted the injured
tissue, serving
to inactivate the complement system and reduce inflammation and neuronal
damage.
«Widespread blocking of this part of the immune system after
traumatic brain injury helps
damaged brain
tissue to survive and improves neurological recovery in mice.
Uncontrolled, excessive inflammation contributes
to the secondary
tissue damage of
traumatic spinal cord, and HMGB1 is highlighted for initiation of a vicious self - propagating inflammatory circle by
Studies have shown that
traumatic brain lesions (i.e.
damaged brain
tissue) can occur in whiplash injuries, but typically will not occur without a high magnitude of acceleration - deceleration and are unlikely
to occur without a significant loss of consciousness.
A pedestrian vs. motor vehicle accident has the potential
to cause death,
traumatic brain injuries, disfigurement, scarring, muscle and
tissue damage, nerve
damage, loss of a limb, depression and other physical and mental impairments.