«Pancreatic cancer is extremely hard to
treat by chemotherapy, so this finding is important because vitamin A targets the non-cancerous tissue and makes the existing chemotherapy more effective, killing the cancer cells and shrinking tumours.
In the study, patients who received cediranib in addition to chemotherapy had greater tumour shrinkage than
those treated by chemotherapy plus placebo (66 % versus 42 %).
Not exact matches
Doxorubicin is a
chemotherapy drug used to
treat a wide range of cancers
by preventing cancer cells from replicating.
«Cervical cancer patients are currently
treated as a uniform group based on
chemotherapy and radiation regimens that help the largest percentage of people; however, one third of these patients are not helped
by standard therapies,» Banister said.
«
By treating with
chemotherapy, we're driving cells through a transition state and creating vulnerabilities,» said first author Aaron Goldman, PhD, a postdoctoral fellow in biomedical engineering at BWH.
They compared the effectiveness of the combination treatments with just
treating the leukemia
by chemotherapy or inhibitors alone.
«They also suggest that low - dose metronomic
chemotherapy or targeting the chemokine signaling mediated
by chemo -
treated fibroblasts may improve the therapeutic outcome in desmoplastic cancers.»
By the time of diagnosis the majority of women with ovarian cancer already have extensive spread of the disease which makes it difficult to treat by surgery or chemotherap
By the time of diagnosis the majority of women with ovarian cancer already have extensive spread of the disease which makes it difficult to
treat by surgery or chemotherap
by surgery or
chemotherapy.
In one example highlighted
by the researchers, mouse models of T - ALL were
treated either with a combination of mTOR inhibitor pp242 and the
chemotherapy drug AraC, or they were
treated with just AraC or pp242.
A blood cancer characterized
by the rapid growth of abnormal white blood cells, AML is typically
treated with
chemotherapy, in some cases followed
by a stem cell transplant.
The addition of high doses of a form of vitamin A could help make
chemotherapy more successful in
treating pancreatic cancer, according to an early study
by Queen Mary University of London (QMUL).
«CRKII most likely regulates the stability of mutated epidermal growth factor receptors and drives cancer growth
by promoting signaling, or communication, within cancer cells,» said Julia Petschnigg, lead author on the paper and a postdoctoral fellow at U of T. «We found that a combinatorial
chemotherapy that inhibits those mutated receptors and CRKII could be beneficial in
treating lung cancer.»
«Drug could limit spread of deadly brain tumors: Study shows PPF could help
treat glioblastomas
by sensitizing tumors to
chemotherapy, radiation treatments.»
A drug used to
treat men with late - stage prostate cancer proved effective in stemming progression of the disease in research participants who had not yet received
chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led
by the Knight Cancer Institute at Oregon Health & Science University (OHSU).
Dronabinol was approved
by the Food and Drug Administration more than 25 years ago to
treat nausea and vomiting in
chemotherapy patients.
As part of the new study, the researchers showed that intact axons without Phr1 were protected from the damage caused
by vincristine, a
chemotherapy drug used to
treat leukemia, neuroblastoma, Hodgkin's disease and non-Hodgkin's lymphoma, among other cancers.
Based on an analysis of existing evidence, published in an opinion article in the Nature Reviews Clinical Oncology journal on January 20, Dr. Narod argues that to achieve a cure, rather than simply delay progression or reoccurrence of the disease, women should be first
treated with aggressive surgery to remove all clinically - detectable cancer cells, followed
by targeted
chemotherapy to the abdomen (intraperitoneal
chemotherapy).
By contrast, a signal of tumor activity increased sixty-fold in mice
treated with the widely used
chemotherapy drug gemcitabine.
They confirmed this
by showing that tumor growth was reduced in mice
treated with an antibody drug that targets TIM - 3 and the
chemotherapy agent paclitaxel, as compared to treatment with paclitaxel alone.
The study
by researchers at King's College Hospital and the University of Southampton suggests that adding nutraceuticals to
chemotherapy cycles may improve the effectiveness of conventional drugs, particularly in hard to
treat cancers, such as pancreatic cancer.
The evidence for benefits was strongest for
treating chronic pain, reducing
chemotherapy - induced nausea and vomiting, multiple sclerosis patients have reported that it reduces spasticity — muscle tightness and movement difficulties — although when the measurements are taken
by a doctor the evidence of reduced spasticity was weaker.
There is «conclusive or substantial evidence» that marijuana or related compounds can effectively
treat chronic pain, nausea caused
by chemotherapy treatment for cancer, and spasticity caused
by multiple sclerosis, according to a report published today
by the National Academies of Sciences, Engineering, and Medicine.
They analyzed the association between body mass index (weight divided
by height) and progression - free survival (PFS) and overall survival (OS) in six independent cohorts of patients
treated with targeted therapy, immunotherapy or
chemotherapy in pivotal trials that led to FDA approval of these drugs.
The multicentre trial included 153 patients with surgically - treatable malignant pleural mesothelioma, who were first
treated with three
chemotherapy cycles of cisplatin and pemetrexed, followed
by surgical removal of affected lung tissue, with the goal of complete removal of the cancerous areas of lung.
Colorectal cancer (cancer of the colon / rectum) can be successfully
treated by surgical resection of the metastases in combination with
chemotherapy.
However the team from the Krebs Institute for Nucleic Acids at the University of Sheffield found that the key to preventing resistance to a common class of
chemotherapy used to
treat breast and colon cancer is to change the speed in which the cancer cells repair damage to their DNA that is introduced
by chemotherapy.
A stem cell - based method created
by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of
chemotherapy by treating the disease in a more localized way.
«These tumors occur in up to 23,000 Americans annually, and are typically
treated with surgical resection of the tumor followed
by chemotherapy and radiation treatment.»
«Transplantation allows clinicians to
treat the cancer most effectively
by using more intense doses of
chemotherapy than can typically be given, while avoiding fears of wiping out the bone marrow.
The study, led
by Deborah Armstrong at the Johns Hopkins Kimmel Cancer Center in Baltimore, Maryland, builds upon evidence from eight other clinical trials showing an overall survival benefit of approximately one year for women
treated with IP
chemotherapy after «optimal debulking» — surgery to remove most, if not all, of the cancer in the abdomen.
Difficult to
treat and aggressive «triple - negative» breast cancer is chemoresistant even before
chemotherapy begins, a new study
by researchers from Karolinska Institutet and the University of Texas MD Anderson Cancer Center...
Glioblastoma is typically
treated with surgery, followed
by radiation and
chemotherapy.
Research
by the Baruch S. Blumberg Institute's Pennsylvania Cancer and Regenerative Medicine Research Center suggests that the use of HIV drugs can allow for lower doses of
chemotherapy in
treating breast cancer, reducing side effects
ARANESP ® is also used to
treat anemia caused
by chemotherapy used to
treat some types of cancer.
A
chemotherapy drug used to
treat brain cancer may increase vulnerability to depression
by stopping new brain cells from growing, according to a new King's College London study out today in Translational Psychiatry.
The addition of high doses of a form of vitamin A could help make
chemotherapy more successful in
treating pancreatic cancer, according to an early study
by Queen Mary University of London.
Patients are asked to take part in this research study because they have esophageal and gastroesophageal junction cancer
treated with
chemotherapy and radiotherapy followed
by surgery (resected), but still have residual disease in resected tissue.
«We also identified a way to inhibit the SOX9 stabilization
by treating the tumors with small molecular drugs, which made them less resistant to
chemotherapy again.»
Patients are
treated by a multi-disciplinary team that may include medical oncologists, radiation oncologists, surgical oncologists, neuro oncologists, internal medicine, family practice and radiology; board certified surgeons who are specialists in reconstructive, gynecologic, urologic and neurologic surgery; nurses specially trained in cancer treatment and certified to administer
chemotherapy, counselors, who address a full range of psychosocial needs from diagnosis through bereavement; clergy to support all faiths; physical, occupational, speech and nutritional therapists.
We conducted a meta - analysis in nonmetastatic breast cancer patients
treated by neoadjuvant
chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (CTC) detection as a prognostic marker.
The standard of care for locally advanced, which is usually
treated by radiation and
chemotherapy combination.
So much so, a type of fiber found in shiitake mushrooms is approved for use as adjunct
chemotherapy, injected intravenously to help
treat a variety of cancers
by rallying our immune defenses.
Zadaxin ® is used to
treat hepatitis B and C, and has been studied extensively for its ability to support an immune system that has been suppressed
by chemotherapy in cancer patients.
Inflammatory breast cancer is generally
treated first with systemic
chemotherapy to help shrink the tumor, then with surgery to remove the tumor, followed
by radiation therapy.
It did however spread to liver (another operation) and lung — the latter was caught very early, no op but seems to have been successfully
treated by second, recent,
chemotherapy.
TUESDAY, March 28, 2017 (HealthDay News)-- Zejula (niraparib) has been approved
by the U.S. Food and Drug Administration to
treat adult women with recurring cancers of the ovaries, fallopian tubes or abdominal wall (peritoneum) whose tumors have shrunk in response to platinum - based
chemotherapy.
Antiemetics: The antiserotonergic drugs that act on the serotonin receptors, such as ondansetron (Zofran), are important for
treating nausea caused
by chemical toxins, including drugs used in
chemotherapy and general anesthesia.
These rays are used to kill cancer cells, shrink tumors, and
treat cancers that are not affected
by chemotherapy or safely removable
by surgery.
Chemotherapy in Pets Might Not Be What You Think
By Jocelyn Axelson, CVT Olive, a nine - year - old mixed - breed rat terrier, first came with her family to our oncology department in September 2016 looking for options to
treat her recently diagnosed lymphoma.
This type of lymphoma is often
treated with an oral
chemotherapy agent that is administered
by the owner at home.