The researchers at Sandia and the university did molecular computer simulations to predict what mutations would produce that desirable result when introduced into the enzyme - drug L - ASN2, commonly used to
treat certain types of leukemia.
It is approved by the U.S. Food and Drug Administration (FDA) for
treating certain types of leukemia and is helpful in other conditions that require immunosuppressive therapy.
Not exact matches
The first gene therapies approved in the United States are
treating patients with
certain types of leukemia and lymphoma.
Half
of the patients
treated in this study responded to either ponatinib (typically used for
certain types of leukemia) or pazopinib (a kidney cancer drug), depending on the genetic alterations identified through sequencing.
The drugs used, pazopanib (top) and ponatinib, are typically used to
treat kidney cancer and
certain types of leukemia, respectively.