They found that estrogen inhibition both prevented and
treated PAH in BMPR2 mutant mice, associated with a reduction in metabolic defects including oxidized lipid formation and insulin resistance.
United Therapeutics chairman and CEO Martine Rothblatt said, «We are optimistic about acquiring SteadyMed and adding Trevyent to our pipeline of products to
treat PAH.
By monitoring microRNA regulation, they can tell how well ataluren is working to
treat PAH.
Not exact matches
Woo's technique may one day be used to
treat the metabolic disorder phenylketonuria (PKU), in which the gene for the hepatic enzyme known as phenylalanine hydroxylase (
PAH) is defective.
Woo intends to transplant these cells into the
PAH - deficient mice to see whether they can
treat PKU in the animals.
Patients with cases of primary pulmonary hypertension (PPH) or primary arterial hypertension (
PAH) that do not respond to medical therapy may need to undergo a single or double lung transplant operation in order to
treat their condition.