To understand how and why, Artyomov, first author Monika Bambouskova, PhD, a postdoctoral researcher at Washington University, Alexey Sergushichev, PhD, a researcher at ITMO University in St. Petersburg, Russia, and colleagues
treated inflammatory cells from mice and people with dimethyl itaconate, a modified form of itaconate.
Not exact matches
«Our study results are the first to argue that we may be able to
treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of
cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.
«xIAP has other roles in the
cell, such as regulation of
cell death, so it is a tricky target for
treating inflammatory diseases.
«ILCs were discovered less than a decade ago, but the parallels between them and T
cells will enable us to more quickly understand how they work and to develop ways to enhance or inhibit their function in
treating a variety of immune and
inflammatory diseases.»
Researchers compared the
inflammatory response of control -
treated versus simvastatin -
treated cells to RV by measuring CXCL10 secretion, an implicated therapeutic target for virus - induced asthma exacerbations.
«Someday we might
treat GERD with medications that target the cytokines or
inflammatory cells that really cause the damage to the esophagus,» said co-senior author Dr. Rhonda Souza, Professor of Internal Medicine at UT Southwestern and staff physician with the Department of Gastroenterology at the Dallas VA Medical Center.
Nine patients were
treated with tocilizumab, an immunosuppressant drug that blocks the effects of the
inflammatory cytokine IL - 6, which have been found to spike during the most robust phase of the engineered
cells» expansion in the body.
There are plans for human trials using stem
cell therapy to
treat inflammatory mouth disease as early as next year.
We have a lot of work ahead of us, but I can see using these
cells to reduce scar formation, improve wound healing, and even
treat many
inflammatory and autoimmune diseases.»
In our latest work, for example, we have found evidence of a potentially clinically useful connection of complement in mesenchymal stem
cell - based therapies, suggesting that complement is a valid target for improving the viability and function of mesenchymal stem
cells, which are under extensive evaluation in clinical trials for
treating many
inflammatory and degenerative diseases.
Plasmapheresis can be used to
treat a variety of disorders including: myasthenia gravis, Guillan - Barre syndrome, chronic
inflammatory demyelinating polyneuropathy, Lamber - Eaton myasthenic syndrome, sickle
cell disease, certain forms of neuropathies, Wilson's disease, and thrombotic thrombocytopenic purpura.
ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem
cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for
treating wounds in the gut that can be caused by disorders such as
inflammatory bowel disease (IBD).
These
cells play a huge role in our
inflammatory response, and shutting them down could help us
treat inflammatory disease like IBS and arthritis.
Arafat and her team discovered that when they
treated pancreatic tumors (developed in animals for the study) with thymoquinone, 67 % of the tumors shrunk significantly, and levels of
inflammatory markers in the
cells dropped substantially.
ClearZine is not a solution for acne scars or rosacea, but it may help
treat these sensitive skin problems as collagen plays a role in the development and regrowth of new skin
cells and the antioxidants in this stack may help reduce inflammation as rosacea is an
inflammatory disease.
Chronic stress suppresses your immune system, specifically your T -
cells which recruit
cells to an infection and help to ensure that the magnitude of an immune response is adequate.1 Cortisol is also anti -
inflammatory.1 Anti-
inflammatory interventions are often a good thing when they're being to used to
treat conditions where there is chronic inflammation.
«a major active polyphenol of green tea, has been shown to down - regulate
inflammatory responses in dendritic
cells (DCs)... In addition, EGCG -
treated DCs inhibited lipopolysaccharide (LPS)- induced production of pro-
inflammatory cytokines» Also apropos: «Autoimmunity, dendritic
cells and relevance for Parkinson's disease» http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535404/
Results from the clinical trial recently appeared in the journal Stem
Cells Translational Medicine and are the first to demonstrate the safety and efficacy of treating a naturally occurring, chronic inflammatory disease in cats with their own fresh, fat - derived stem c
Cells Translational Medicine and are the first to demonstrate the safety and efficacy of
treating a naturally occurring, chronic
inflammatory disease in cats with their own fresh, fat - derived stem
cellscells.
He was
treated with stem
cells for several medical problems including allergic rhinitis,
inflammatory bowel disease (IBD), chronic renal disease, and diabetes.