Not exact matches
Why have we made more progress on certain
diseases while other mass - scale killers, like chronic obstructive pulmonary
disease (COPD), are largely off
of people's radars and so difficult to
treat in an
age of therapies which can resemble magic?
While substantial progress has been made in preventing, diagnosing, and
treating certain S - TDs in recent years, CDC estimates that approximately 19 million new infections occur each year, almost half
of them among young people
ages 15 to 24.1 In addition to the physical and ps - ychological consequences
of ST - Ds, these
diseases also exact a tremendous economic toll.
While sub-stantial progress has been made in preventing, diagnosing, and
treating certain ST - Ds in recent years, CDC estimates that approximately 19 million new infections occur each year, almost half
of them among young people
ages 15 to 24.1 In addition to the physical and psy - chological co-nsequences
of S - TDs, these
diseases also exact a tremendous economic toll.
While substantial progress has been made in preventing, diagnosing, and
treating certain S - TDs in recent years, CDC estimates that approximately 19 million new infections occur each year, almost half
of them among young people
ages 15 to 24.1 In addition to the physical and psychological consequences
of S - TDs, these
diseases also exact a tremendous economic toll.
It is important for physicians and scientists to understand the unique pathology
of HS -
AGING, and to be able to differentiate it from other
diseases, as it is only by making an accurate diagnosis that clinicians can hope to
treat people who present with signs
of cognitive decline.
But the
treated 70 - to 79 - year - olds had 19 more heart
disease cases and 13 more strokes per 10,000 women annually than women
of the same
age taking a placebo.
«If proven true, then combined use
of metformin and rapamycin for
treating aging and
age - associated
diseases in humans may be possible,» the researchers wrote in their conclusion.
For example, in the combined hormone therapy trial,
treated 50 - to 59 - year - olds had five additional cases
of heart
disease and five more strokes per 10,000 women annually compared with the same -
aged group on placebo.
For patients with Crohn's
disease, researchers found a significantly higher risk
of cervical neoplasia in patients diagnosed at a young
age and in patients
treated with azathioprine.
The study, published online ahead
of print in The Journal
of Clinical Investigation, has implications for
treating diseases such as diabetic retinopathy and
age - related macular degeneration — the leading causes
of vision loss in adults.
«It's fantastic news that they are going into the clinic with a cell therapy for eye
disease,» says Pete Coffey
of University College London, and head
of a team developing tiny «patches»
of RPEs for
treating age - related macular degeneration.
«The excitement is due in part to the
aging of society and the potential for
treating chronic
diseases associated with
aging,» he says.
Results indicated that after correcting for lung
disease as well as other factors that can contribute to ROP risk such as gestational
age, there is still a higher risk
of ROP in steroid -
treated infants than in those infants not
treated with steroids.
The identification
of factors that slow the
age - dependent deterioration
of the neurogenic niche in mice may constitute the basis for new methods
of treating age - related neurodegenerative and neurovascular
diseases.
Helen Thomson writes that transfusions
of young blood may help
treat age - related conditions such as Alzheimer's and heart
disease (23...
The experimental drug J147 is something
of a modern elixir
of life; it's been shown to
treat Alzheimer's
disease and reverse
aging in mice and is almost ready for clinical trials in humans.
The U.S. FDA recently approved Genentech's Lucentis for treatment
of wet
age - related macular degeneration and Genzyme's Myozyme for
treating Pompe
disease, a rare neuromuscular condition.
«Everybody else hopes that you can make use
of that [nerve cell production] to
treat neurodegenerative
diseases,» such as Parkinson's
disease, or even to encourage the
aging brain to regenerate by stimulating the production
of new nerve cells, he says.
Dillin noted that drugs that lower levels
of serotonin have long been used to
treat depression and other psychiatric manifestations
of neurodegenerative
diseases, but the new findings suggest these medications may have more widespread use in
age - related
disease than was previously thought.
The study, published September 7 in Nature Medicine, provides promise for a new therapeutic approach to
treating the millions
of people suffering from muscle
diseases, including those with muscular dystrophies and muscle wasting associated with cancer and
aging.
If it does a similar job in humans, it could have huge potential for
treating a wide - range
of age - related
diseases, say the researchers behind the latest work.
«GSK is betting that we have discovered a whole new class
of drugs that will
treat all or many
diseases of aging at once,» says Christoph Westphal, CEO and cofounder
of Sirtris.
Potential new approaches to
treating eye
diseases such as
age - related macular degeneration (AMD) are described in a new study, «IL - 33 amplifies an innate immune response in the degenerating retina,» in the February Journal
of Experimental Medicine.
Researchers in nanomedicine have long dreamed
of an
age when molecular - scale computing devices could be embedded in our bodies to monitor health and
treat diseases before they progress.
LA JOLLA — A study tying the
aging process to the deterioration
of tightly packaged bundles
of cellular DNA could lead to methods
of preventing and
treating age - related
diseases such as cancer, diabetes and Alzheimer's
disease, as detailed April 30, 2015, in Science.
Retinal degenerative
diseases, including
age - related macular degeneration and Retinitis Pigmentosa (RP) are the predominant causes
of human blindness worldwide and are very difficult to
treat.
SAN FRANCISCO, CA — A scientific team led by the Gladstone Institutes and UC San Francisco has discovered that a common form
of a gene already associated with long life also improves learning and memory, a finding that could have implications for
treating age - related
diseases like Alzheimer's.
«Scientists from the Florida campus
of The Scripps Research Institute (TSRI) have made an important discovery toward the development
of drugs to
treat age - related memory loss in
diseases like Alzheimer's.
A passionate believer in the power
of regenerative medicine to not only
treat disease but also to cure it, Dr. Bosarge launched Black Beret Life Sciences, LLC in 2014, leading research for treatments based on regenerative medicine for cancer, diabetes, neurodegeneration, osteoarthritis, and other conditions related to
aging.
Reducing the use
of indoor tanning by enforcing an
age restriction could potentially reduce melanoma incidence, mortality, and the costs associated with
treating the
disease, according to results
of an economic analysis published in the Journal
of the American Academy
of Dermatology.
Reducing the use
of indoor tanning by enforcing an
age restriction could potentially reduce melanoma incidence, mortality, and the costs associated with
treating the
disease, according to results
of an economic analysis.
In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in
aging mice and mouse models
of age - related
disease, exploiting the high dependence
of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation
of new blood and immune precursor cells11 in
aging mice to near youthful norms, and prevented or
treated mouse models
of diseases of aging like osteoarthritis, 12 fibrotic lung
disease, 13 hair loss, 14 atherosclerosis, 15,16 and
age - related
diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.
[19] In the current study, [15] PDGF - AS mice exhibited an increased number and intensity
of areas staining for reactive microglia (using Iba1) and astroglia (using GFAP), but vaccination with AFF 1 prevented nearly all
of this
disease - associated excess, with
treated animals exhibiting only the burden
of reactive glia present in similar -
aged WT mice.
Panelists will discuss how scientists are investigating what happens to these cells as we
age, how this knowledge is being used to guide new strategies to boost brain health and to develop therapies utilizing stem cells to
treat diseases of the brain.
UNITY Biotechnology Launches with a Focus on Preventing and Reversing
Diseases of Aging February 03, 2016 SAN FRANCISCO --(BUSINESS WIRE)-- UNITY Biotechnology today announced that it is developing medicines to
treat and eliminate
age - related
diseases and increase healthspan, or the amount
of time an individual lives in good health.
LA JOLLA — The experimental drug J147 is something
of a modern elixir
of life; it's been shown to
treat Alzheimer's
disease and reverse
aging in mice and is almost ready for clinical trials in humans.
We are focused on the discovery, development and commercialization
of cell based therapeutics that prevent,
treat or cure
disease by repairing and replacing damaged or
aged tissue, cells and organs and restoring their normal function.
Boosted by a newly funded grant from the NIH's National Institute
of Aging, he will start with his project to repurpose a heart
disease drug to
treat Alzheimer's
disease.
Understanding the elderly patient and figuring out modes
of intervention to better prevent and
treat disease associated with
aging will continue to be an important area
of research.
It can only be
treated by replacing the valve through heart surgery and is the third leading cause
of heart
disease, affecting three percent
of adults over the
age of 75.
Research on these issues has drawn funding from the likes
of Google, while the Bay Area's Unity Biotechnology, which is developing drugs to
treat diseases that accompany
aging, has also raised a bunch
of money.
The Alzheimer's
Disease Neuroimaging Initiative (ADNI) is a historic study of brain aging looking to help increase the pace of discovery in the race to prevent, treat and one day cure Alzheimer's d
Disease Neuroimaging Initiative (ADNI) is a historic study
of brain
aging looking to help increase the pace
of discovery in the race to prevent,
treat and one day cure Alzheimer's
diseasedisease.
These criteria may include gender,
age, type
of disease being
treated, previous treatments, and other medical conditions.
LA JOLLA — A study tying the
aging process to the deterioration
of tightly packaged bundles
of cellular DNA could lead to methods
of preventing and
treating age - related
diseases such as cancer,...
«This is a great start to the fall giving season and we look forward to more fundraising efforts to support our mission
of transforming the way the world researches and
treats age - related
diseases.»
Presence
of FMc was
treated as a binary outcome in logistic regression models, with
age at diagnosis and various
disease characteristics as the predictors.
Mipomersen (Kynamro) reduces low - density lipoprotein (LDL) cholesterol by silencing a gene that produces apolipoprotein B - 100, a building block
of LDL; the drug can
treat familial hypercholesterolemia, an inherited
disease that may cause heart attacks at an early
age.
Designing better systems for detection and safe removal
of dysfunctional «senescent» cells to improve health and
treat age - related
diseases.
More specifically, beets can boost blood flow, help
treat anemia, regulate cholesterol levels, promote healthy liver function, decelerate
aging, enhance digestion and decrease the risk
of cancer and heart
disease.
Being diagnosed with a «progressive and incurable» neurological
disease at the
age of 23 has been my greatest burden but also my greatest gift because
of the juicy life lessons I have learned through the daily and sometimes menacing struggles
of living with,
treating and healing from a debilitating and disabling
disease.