But this requires fibre optic cables to be implanted in the brain, which is impractical for
treating human brain disorders.
These results are the first implication that Lef1 functions in the hypothalamus to mediate behavior, knowledge that could prove useful for diagnosing and
treating human brain disorders.
Not exact matches
Eric Topol speaks with Edward Boyden about the promise of optogenetics, from
treating common
brain disorders to unlocking what it means to be
human.
A recent study published in Annals of Neurology reports that healthy
human tissue grafted to the
brains of patients with Huntington's disease in the hopes of
treating the neurological
disorder also developed signs of the illness, several years after the graft.
By doing so, members of Gould's laboratory pinpointed
brain cells and regions important to anxiety regulation that may help scientists better understand and
treat human anxiety
disorders, she said.
By getting down to synaptic levels in the
brain — even if only in mice — the researchers seem to have taken a step toward explaining why omega - 3 trials in
humans have shown some success in
treating mood
disorders.
The discovery may help explain why
humans evolved more elaborate
brains than mice, and it could suggest ways to
treat disorders such as autism and epilepsy that arise from abnormal neural development.
«This is the first instance I am aware of where an academic drug discovery group moved a molecule designed to hopefully
treat a chronic
brain disorder all the way from early discovery to
human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD).
Both are being used to prevent and reverse dementia, improve cognitive function, increase
human growth hormone (hGH) release, and to
treat brain disorders such as damage from stroke.
Long desired by researchers seeking new ways to
treat, cure, and even prevent
brain disorders, this picture will fill major gaps in our current knowledge and provide unprecedented opportunities for exploring exactly how the
brain enables the
human body to record, process, utilize, store, and retrieve vast quantities of information, all at the speed of thought.