Sentences with phrase «treating human cancers»

While SRS is widely available for treating human cancers — with the intent to cure — the veterinary field has a limited supply of advanced technology and services for treating the growing number of pets with cancer.

Finding answers to these questions may go a long way toward preventing and treating human cancers.

«This new library has direct relevance to treating canine cancer, but it also has indirect relevance to treating human cancer,» Gustafson says.

In all, these studies further consolidate the concept that autophagy inhibition can be exploited to treat human cancers.

The Gerson Institute in southern California has been using this premium calcium montmorillinite to treat human cancer patients with internal tumors successfully.

Not exact matches

Depends whether human nature is using it to treat cancer or build nuclear bombs.

It must be addressed as a result of the fall, like Cancer, which is treated though God's working through human agents and rarely through miraculous intervention.

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

Recent collaborative work between UCR and Cedars - Sinai Medical Center in Los Angeles demonstrated that in animal models of human breast cancer, mice treated with 123B9 that was conjugated with paclitaxel had significantly fewer circulating cancer cells in the blood compared to mice that were not treated or even treated with paclitaxel alone.

ALCOHOL abuse could be treated with cancer drugs, if they work the same way in humans as they do in fruit flies.

Human tumor cells (red) growing in a zebrafish embryo may help doctors choose how to treat cancer patients.

Moreover, epalrestat, a drug that inhibits AKR1B1 and is approved in Japan to treat peripheral neuropathies associated with diabetes, was similarly able to block the growth and metastasis of human basal - like breast cancer cells.

The findings imply that radiation could be especially effective in treating human breast cancers caused by similar mutations.

Its storied history includes its packaging for human trials of a failed cancer drug, azidothymidine (AZT), in the 1980s, after a young NIH investigator named Sam Broder — later director of the National Cancer Institute — decided to investigate whether it would work to treatcancer drug, azidothymidine (AZT), in the 1980s, after a young NIH investigator named Sam Broder — later director of the National Cancer Institute — decided to investigate whether it would work to treatCancer Institute — decided to investigate whether it would work to treat AIDS.

«Lots of ideas and efforts have been made to use NSAIDs to treat human pathologies, including colorectal cancer and other diseases,» Miller said.

Moreover, this approach was effective in treating mice with malignant colorectal cancer tumors containing Kras and p53 mutations, which are found in about half of colorectal tumors in humans.

More recently, HCQ has shown promise in treating pancreatic cancer patients in ongoing clinical trials; however, its tolerability and effectiveness to stop autophagy in humans with other cancers has not been shown before.

Human «organs on chips» could be linked to make the ideal guinea pig, revolutionising the way drugs are tested and cancer is treated

This nanoparticle — one - thousandth the width of a human hair — carries a load of a lethal chemical: docetaxel, which is currently used to treat prostate cancer.

Due to major advances in their immune potency DNA vaccines are being studied in human clinical trials for treating cancer and infectious diseases.

Human breast tumors transplanted into mice are excellent models of metastatic cancer and are providing insights into how to attack breast cancers that no longer respond to the drugs used to treat them, according to research from Washington University School of Medicine in St. Louis.

In a letter published in the cancer journal Annals of Oncology, researchers led by Professor Jean - Philippe Spano, head of the medical oncology department at Pitie - Salpetriere Hospital AP - HP in Paris, France, report that while treating an HIV - infected lung cancer patient with the cancer drug nivolumab, they observed a «drastic and persistent decrease» in the reservoirs of cells in the body where the human immunodeficiency virus (HIV) is able to hide away from attack by anti-retroviral therapy.

DFMO is being investigated in human clinical trials to treat some types of cancer, but it hasn't been tested as a potential therapy for Alzheimer's.

And with non-melanoma skin cancers being the most frequent human tumors, there is clearly a tremendous need to understand the underlying molecular mechanisms, to allow the development of drugs to treat these types of cancer.

In a paper published online May 17, 2016 in the journal Nature Communications, de Jong and co-first author Koji Taniguchi, MD, PhD, and colleagues, report that treating both ERK1 / 2 and the compensatory pathway, ERK5, concurrently with a combination of drug inhibitors halted colorectal cancer growth more effectively in both mouse models and human colorectal cancer cell lines.

«More research is needed to evaluate the efficacy of this use of a cancer medication to alleviate risk of sudden cardiac death, but we are hopeful that what we observed in mice will translate effectively to humans, providing patients and clinicians with a new paradigm for treating this common and life - threatening illness,» Dudley said.

Dr. Bauman and her colleagues treated human head and neck cancer cells in the laboratory with varying doses of sulforaphane and a control, and compared them to normal, healthy cells that line the throat and mouth.

This week it emerged that the first human test of the controversial gene - editing technique CRISPR had taken place at West China Hospital in Chengdu, where oncologists used it to treat a man with an aggressive lung cancer.

Dr. Sadelain's research focuses on human cell engineering and cell therapy to treat cancer and hereditary blood disorders.

A new study from the University of Illinois reports long - lasting cognitive impairments in mice when they are administered a chemotherapy regimen used to treat breast cancer in humans.

This study provides one of the first animal models to demonstrate the long - term cognitive deficits resulting from a chemotherapeutic treatment used in treating humans for breast cancer.

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

They immunized them with the antigen α - fetoprotein, which is found in 70 - 80 percent of human liver cancers, and serves as both a biomarker for diagnosing and a target for treating the sixth most common cancer worldwide, He says.

For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respectively.

Panitumumab (Vectibix), a human anti-human EGFR monoclonal antibody to treat metastatic colorectal cancer, is approved by the FDA.

In another experiment, treating human brain cancer cells containing FGFR3 - TACC3 with mitochondrial inhibitors interrupted the production of energy inside cancer cells and significantly slowed tumor growth.

Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations.3

CSHL is a private, non-profit research and education institution dedicated to exploring molecular biology and genetics in order to advance the understanding and ability to diagnose and treat cancers, neurological diseases, and other causes of human suffering.

Wang's team discovered that if human lung cancer cells in a lab dish in the presence of the receptor were treated with BCX, they migrated less than untreated ones.

«In particular, his approach can be thought of as a very advanced biological therapy for the treatment of breast cancer; one that uses viruses, which are better recognized to cause disease, to treat human breast cancers.»

Bottom Line: Young mice that received molecularly targeted therapies used to treat brain cancer in human patients sustained cognitive and behavioral deficits, but the deficits were largely reversible through environmental stimulation and physical exercise.

EOS100850 potently rescues Th1 cytokine production in human whole blood treated by A2A agonists, and increased CD8 + T cell cytotoxicity in a co-culture assay of effector CD8 + T cells and target cancer cells

He said traditional drugs to treat tapeworm infection — which target the whole organism at the larval stage - might not have been effective against tapeworm cancer cells, and it's also unclear whether chemotherapy for normal human cancer cells could have helped shrink the tumors.

Production of CCS1477 in capsule form is now complete, ahead of forthcoming first - in - human clinical trials to investigate the novel drug's tolerability and efficacy in treating late stage prostate cancer (CRPC).

He and his colleagues were the first to demonstrate that human antigen - specific T cell clones could be isolated and expanded in vitro and then re-infused into patients to prevent or treat viral infections and to mediate therapeutic responses in patients with cancer.

The study provides a new path forward in human research as about half of the breast cancers treated with this common cancer therapy do not respond well, say researchers at the Georgetown Lombardi Comprehensive Cancer Center, who led the multi-institutional rescancer therapy do not respond well, say researchers at the Georgetown Lombardi Comprehensive Cancer Center, who led the multi-institutional resCancer Center, who led the multi-institutional research.

The first UK license for CRISPR / Cas9 use in editing genes in human embryos was granted in 2016, xvii and CRISPR - edited cells to treat lung cancer were administered in the world's first human trials for the technique by a Chinese group in late 2016.

These tumor suppressor genes are two of the most frequently altered genes in human cancer, and understanding how they function at the molecular level will both refine our fundamental understanding of this disease and suggest novel therapeutic approaches to treat it.

Recent advances in our knowledge of human genetics have enabled us to consider new approaches to how we treat cancer.