Not exact matches
Eric Topol speaks with Edward Boyden about the promise of optogenetics, from
treating common brain
disorders to unlocking what it means to be
human.
Benyshek is now researching the public health implications, the likely course of placentophagy throughout
human evolution, whether placentas can
treat mood
disorders and hormonal imbalances, and any potential risks.
«Now that we've confirmed the
human relevance of our findings, our future goal is to better understand the roles of the different cell types in psychiatric and neurological
disorders, and to determine if targeting these cells can actually help
treat seizures,» concluded Paz.
A recent study published in Annals of Neurology reports that healthy
human tissue grafted to the brains of patients with Huntington's disease in the hopes of
treating the neurological
disorder also developed signs of the illness, several years after the graft.
By doing so, members of Gould's laboratory pinpointed brain cells and regions important to anxiety regulation that may help scientists better understand and
treat human anxiety
disorders, she said.
By getting down to synaptic levels in the brain — even if only in mice — the researchers seem to have taken a step toward explaining why omega - 3 trials in
humans have shown some success in
treating mood
disorders.
These results are the first implication that Lef1 functions in the hypothalamus to mediate behavior, knowledge that could prove useful for diagnosing and
treating human brain
disorders.
The real test, Conboy says, will come in clinical trials that aim to block B2M — or other related molecules — to
treat or prevent memory
disorders in
humans.
If the findings translate to
humans, they could lead to new ways to
treat depression, anxiety, and other mental
disorders.
But this requires fibre optic cables to be implanted in the brain, which is impractical for
treating human brain
disorders.
The study helps explain a distinctly
human mechanism of cognition, said the lead researchers at Brown University, and could be applied to studying and
treating reward - seeking or punishment - avoidance conditions such as addiction or obsessive - compulsive
disorder.
«Future studies on how PAF / PAFR signaling controls UCP1 levels through beta3 - AR production in the BAT of animals and
humans may reveal new therapeutic targets to
treat metabolic
disorders associated with obesity,» said Junko Sugatani, Ph.D., a researcher involved in the work from the Department of Pharmaco - Biochemistry at the School of Pharmaceutical Sciences at the University of Shizuoka in Shizuoka, Japan.
When a team of South Korean scientists announced in February that they had successfully derived stem cells from a cloned
human embryo, they trumpeted the potential someday to
treat disorders from diabetes to spinal cord injuries.
They verified that blood concentration levels were comparable to effective levels in
humans being
treated for bipolar
disorder or mania, and then administered the open field and other behavioral tests.
Dr. Sadelain's research focuses on
human cell engineering and cell therapy to
treat cancer and hereditary blood
disorders.
«Mouse behavior isn't the same as
human behavior, so we need to be cautious, but we were surprised and heartened by the fact that the mutant mice responded to lithium treatment — a gold standard for
treating human bipolar
disorder and alleviating features of mania and depression,» says Christopher Ross, M.D., Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.
The results suggest that this strategy could one day
treat muscular dystrophy in
humans as well as other genetic
disorders.
If the «substrate - selective» COX - 2 inhibitors developed at Vanderbilt also work in
humans without side effects, they could represent a new approach to
treating mood and anxiety
disorders, the researchers conclude in a paper to be posted online Sunday in the journal Nature Neuroscience.
The discovery may help explain why
humans evolved more elaborate brains than mice, and it could suggest ways to
treat disorders such as autism and epilepsy that arise from abnormal neural development.
Once we understand these molecular changes we can work on creating interventions that could help protect the heart in space, and potentially help us
treat cardiovascular
disorders in
humans on Earth as well.»
«This is the first instance I am aware of where an academic drug discovery group moved a molecule designed to hopefully
treat a chronic brain
disorder all the way from early discovery to
human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDD).
A team from Duke University has used the gene editing tool — hailed as Science magazine's 2015 Breakthrough of the Year — for the first time to
treat the genetic
disorder Duchenne muscular dystrophy inside a living mammal, to be potentially replicated in
humans.
This noninvasive approach could pave the way to using optogenetics in
human patients to
treat epilepsy and other neurological
disorders, the researchers say, although much more testing and development is needed.
and of
human ESCs (hESCs) in 1998 by Jamie Thomson, present - day use of hESCs to
treat patients with retinal
disorders in London (although I shuddered a little when Pete Coffee handled a flask of cells without gloves on!)
Back when stem cells were first extracted from
human embryos 20 years ago, scientists were fascinated at their ability to change into any type of cell in the body and thought they would soon be used to
treat all types of diseases, from eye
disorders to diabetes.
Lentiviral - based gene therapy methods to modify
human CD34 + hematopoietic stem cells have been investigated as a way of
treating various hematological
disorders including X-linked chronic granulomatous disease (X-CGD).
This research, published in The American Journal of
Human Genetics, could have a significant impact on clinical approaches to
treating this deadly childhood
disorder.
ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from
human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for
treating wounds in the gut that can be caused by
disorders such as inflammatory bowel disease (IBD).
For instance, it's possible to imagine a future in which viruses, optogenetics, and related technologies are harnessed to modulate neural circuits to
treat specific neurological and neuropsychiatric
disorders in
humans.
The Alpert Prize recognizes scientists whose research has led to the prevention, cure or treatment of
human diseases or
disorders, and constitutes a seminal scientific finding that holds great promise of ultimately changing our understanding of, or ability to
treat, disease.
National Institute of Dental and Craniofacial Research (NIDCR)-- Est. 1948 NIDCR provides leadership for a national research program designed to understand,
treat, and ultimately prevent the infectious and inherited craniofacial - oral - dental diseases and
disorders that compromise millions of
human lives.
She joined the Pillai lab as a post-doctoral research fellow in 2016 and continues to enjoy her work both
treating patients with primary immunodeficiency in the clinic and studying the bridging gap between
human primary immunodeficiency
disorders and the development of autoimmune disease pathology in the lab.
Sansbury and Kmiec said that while their work with their CRISPR - Cpf1tool has confirmed its usefulness for reliably editing DNA samples that are part of a diagnostic test, it is not yet fully developed as a therapeutic tool for directly
treating disorders that would involve repairing or removing malfunctioning genes in
humans, animals or plants.
UC Irvine researchers have discovered a dramatically improved method for genetically manipulating
human embryonic stem cells, making it easier for scientists to study and potentially
treat thousands of
disorders ranging from Huntington's disease to muscular dystrophy and diabetes.
However, they say the work at least proves the potential for mRNA therapy to successfully
treat not only hemophilia B but also other
human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system, lung and eyes.
Both are being used to prevent and reverse dementia, improve cognitive function, increase
human growth hormone (hGH) release, and to
treat brain
disorders such as damage from stroke.
Even with all the data showing that it can help boost energy levels, cleanse the blood, heal digestive
disorders, dissolve gallstones,
treat infections, and prevent cancer, some health experts have been reluctant to recommend taking curcumin in medicinal doses until
human clinical trials have been conducted.
For centuries, the energy / information content, in the form of vital mineral elements locked away within these perfectly formed crystals of mineral rich salt, were utilized by doctors for
treating most every
disorder known to
humans, and with unfailing success.
Specification points covered are: Paper 2 Topic 1 (4.5 - homeostasis and response) 4.5.1 - Homeostasis (B5.1 lesson) 4.5.3.2 - Control of blood glucose concentration (B5.1 lesson) 4.5.2.1 - Structure and function (B5.2 lesson) Required practical 7 - plan and carry out an investigation into the effect of a factor on
human reaction time (B5.2 lesson) 4.5.3.1 - Human endocrine system (B5.6 lesson) 4.5.3.4 - Hormones in human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9 le
human reaction time (B5.2 lesson) 4.5.3.1 -
Human endocrine system (B5.6 lesson) 4.5.3.4 - Hormones in human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9 le
Human endocrine system (B5.6 lesson) 4.5.3.4 - Hormones in
human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9 le
human reproduction (B5.10 lesson) 4.5.3.5 - Contraception (B5.11 lesson) 4.5.3.6 - The use of hormones to
treat infertility (HT only)(B5.12 lesson) 4.5.3.7 - Negative feedback (HT only)(B5.13 lesson) Paper 2 topic 2 (4.6 - Inheritance, variation and evolution) 4.6.1.1 - sexual and asexual reproduction (B6.1 lesson) 4.6.1.2 - Meiosis (B6.1 lesson) 4.6.1.4 - DNA and the genome (B6.3 lesson) 4.6.1.6 - Genetic inheritance (B6.5 lesson) 4.6.1.7 - Inherited
disorders (B6.6 lesson) 4.6.1.8 - Sex determination (B6.5 lesson) 4.6.2.1 - Variation (B6.9 lesson) 4.6.2.2 - Evolution (B6.10 lesson) 4.6.2.3 - Selective breeding (B6.11 lesson) 4.6.2.4 - Genetic engineering (B6.11 lesson) 4.6.3.4 - Evidence for evolution (B6.16 lesson) 4.6.3.5 - Fossils (B6.16 lesson) 4.6.3.6 - Extinction (B6.16 lesson) 4.6.3.7 - Resistant bacteria (B6.17 lesson) 4.6.4.1 - classification of living organisms (B6.18 lesson) Paper 2 topic 3 (4.7 - Ecology 4.7.1.1 - Communities (B7.1 lesson) 4.7.1.2 - Abiotic factors (B7.1 lesson) 4.7.1.3 - Biotic factors (B7.1 lesson) 4.7.1.4 — Adaptations (B7.2 lesson) 4.7.2.1 - Levels of organisation (feeding relationships + predator - prey cycles)(B7.3 lesson) 4.7.2.1 - Levels of organisation (required practical 9 - population sizes)(B7.4 lesson) 4.7.2.2 - How materials are cycled (B7.5 lesson) 4.7.3.1 - Biodiversity (B7.7 lesson) 4.7.3.6 - Maintaining Biodiversity (B7.7 lesson) 4.7.3.2 - Waste management (B7.9 lesson) 4.7.3.3 - Land use (B7.9 lesson) 4.7.3.4 - Deforestation (B7.9 lesson) 4.7.3.5 - Global warming (B7.9 lesson)
«Society stands on the precipice of change, as the ability to sequence and study the genomes of
humans and animals is dramatically altering how scientists and doctors study and
treat disease and
disorders,» says Dr. Ganzert.
Background Historically, bromides were licensed and used routinely for
treating seizure
disorders in
humans; however, when phenobarbital was introduced, the
human market for bromides was completely eclipsed.
The study, published in Journal of the American Veterinary Medical Association, provides a better understanding of the prevalence and source of such
disorders, and could advance efforts to prevent and
treat genetic
disorders in both dogs and
humans, the researchers say.
The type of drugs used to
treat Attention Deficit Hyperactivity
Disorder (ADHD) in
humans are stimulants to pets.
Although some practices were dreadful — in
human medicine people would give morphine to their teething babies and
treat mood
disorders with lobotomies!
Nicholas Dodman, an animal behaviorist and veterinarian at Tufts University in Medford, MA, says a drug currently used to
treat dementia in
humans is helpful in
treating an animal form of obsessive - compulsive
disorder, but so far no pharmaceutical company has opted to develop it for the pet market.
Just like the ever - growing list of
disorders, it is known to
treat in
humans, acupuncture also plays a big role in combating some of the side effects that sprout as a result of cancer cells in a dog's body.
In older times, bromides were licensed and used routinely for
treating seizure
disorders in
humans; however, when phenobarbital was introduced, the
human market for bromides was completely eclipsed.
The dog has already played an important role in emerging therapies for inherited blindness in
humans and similarities in disease phenotype and eye structure and function between dog and man, together with the increasingly sophisticated genetic tools that are available for the dog, mean that the dog is likely to play an ever increasing role in both our understanding of the normal functioning of the eye and in our ability to
treat inherited eye
disorders.
Aspirin is a commonly used over the counter nonsteroidal anti-inflammatory drug (NSAID) and is used to
treat fever, pain, inflammation (swelling), and clotting
disorders in
humans.
-- the B.C.
Human Rights Tribunal awarded the complainant, Mr. Gichuru, approximately $ 100,000 in compensation (2011 BCHRT 185) for discrimination by the Law Society, based on the Society asking the complainant on membership application forms about any prior treatment for certain mental conditions including mood
disorders, and how the Law Society consequently
treated him as a result of his disclosing a prior depressive episode.