In addition to being a member of CRI's Clinical Leadership Committee, Dr. Coukos is currently the lead investigator of a CRI - funded clinical trial that is
treating ovarian cancer patients with two immunotherapies — MEDI4736, an anti-PD-L1 checkpoint inhibitor, and motolimod, a TLR8 agonist.
Though smaller in number, some patients with advanced disease and carrying a BRCA mutation may benefit from the same targeted therapy being used today in the clinic to successfully
treat some ovarian cancer patients.»
Not exact matches
«For this reason, we decided to combine vitamin C with a PARP inhibitor, a drug type known to cause
cancer cell death by blocking the repair of DNA damage, and already approved for
treating certain
patients with
ovarian cancer.»
TRINOVA - 2 is evaluating pegylated liposomal doxorubicin in combination with either placebo or trebananib in previously
treated patients with
ovarian cancer while TRINOVA - 3, also known as ENGOT - Ov2 and Gynecologic Oncology Group — 3001, is studying the use of trebananib in front - line treatment adding it to carboplatin / paclitaxel.
Dr. Tordjman and her colleagues studied the effect of radioactive iodine treatment on the
ovarian reserve of women
treated for differentiated thyroid
cancer (DTC) by measuring their blood levels of anti-Müllerian hormone (AMH) and following the
patients for up to one year after treatment.
A section of a tumor organoid grown from cells derived from a
patient with high - grade serous
ovarian cancer (left) and a mini-tumor
treated with ReACp53, resulting in extensive
cancer cell death.
In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found in women with
ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory
cancer by injecting tumor tissues obtained from gynecological
cancer patients treated at the Cancer Institute into laboratory
cancer patients treated at the
Cancer Institute into laboratory
Cancer Institute into laboratory mice.
Recent studies have shown that rucaparib, a PARP inhibitor, effectively
treats patients with platinum - sensitive, relapsed, high - grade
ovarian cancer harboring a BRCA mutation.
The targeted therapy rucaparib, which has demonstrated robust clinical activity in
ovarian cancer patients with a BRCA mutation, also showed promise in previously
treated pancreatic
cancer patients with the mutation, according to results from a phase II clinical study.
Dr. June: We have protocols that will be
treating patients with mesothelioma, pancreatic
cancer, and
ovarian cancer, targeting a protein called mesothelin.
In that randomized, double - blind, placebo - controlled, phase III trial, 561
patients with recurrent epithelial
ovarian, fallopian tube, or primary peritoneal
cancer who were in complete or partial response to platinum - based chemotherapy were
treated with either rucaparib 600 mg orally twice daily (372
patients) or to placebo (189
patients).
The LION trial randomized 650
patients with advanced epithelial
ovarian cancer and macroscopic complete resection to either systematic pelvic and para-aortic LNE (323
patients in intention - to -
treat cohort), or no LNE (324
patients in intention - to -
treat cohort).
Cancer Network presents exclusive coverage on ovarian cancer from the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting, with reports on the latest clinical research changing the way ovarian cancer patients are being managed and tr
Cancer Network presents exclusive coverage on
ovarian cancer from the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting, with reports on the latest clinical research changing the way ovarian cancer patients are being managed and tr
cancer from the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting, with reports on the latest clinical research changing the way
ovarian cancer patients are being managed and tr
cancer patients are being managed and
treated.
A phase II study of allogeneic natural killer cell therapy to
treat patients with recurrent
ovarian and breast
cancer.
Olaparib is a PARP inhibitor, which is already used to
treat certain
ovarian cancer patients and prevents damaged
cancer cells from repairing themselves after chemotherapy or radiotherapy.
At UT Southwestern Medical Center, our gynecologic
cancer experts have unmatched expertise in
treating patients with
ovarian cancer.
May 20, 2015 Study adds diabetes drug with anti-
cancer effect to
ovarian cancer treatment Several recent studies have suggested that metformin, an established drug developed to
treat patients with type II diabetes, may provide significant benefits, including increased survival, to
patients being
treated for advanced
cancers.
«Our study suggests a therapeutic benefit for repurposing a well - tolerated inhibitor with limited toxicity to
treat a specific group of
ovarian cancer patients with high levels of CARM1 expression,» said Sergey Karakashev, Ph.D., first author of the study and a postdoctoral researcher in the Zhang Lab.
Study In 2006 Danish researchers at the University of Copenhagen published in the Scandinavian Journal of Medicine and Science in Sports the results of a study in which they had done experiments with a group of
patients being
treated for intestinal
cancer, breast
cancer,
ovarian cancer and testicular
cancer.
Research shows that hospitals that
treat more than 20
ovarian cancer cases a year and surgeons who operate on more than 10 cases a year have significantly better
patient outcomes than lower volume hospitals and surgeons, according to the Valley Health System.