Sentences with phrase «treatment arms of these studies»

The antiretroviral drugs, of course, can only work if they are in the blood or tissues when HIV attempts to establish an infection, so nonadherent participants who are in treatment arms of these studies make it exceedingly difficult to tease out whether infections occurred because of the drug failure or their own behavior.

Not exact matches

Although Lu - PSMA - 617 put up good numbers in its small single - arm study, it still needs to outperform a physician's choice of approved treatments in a much larger global trial.
Comparisons possible were: 3 studies with treatment arms differing only in the approach (group, individual or self - administered), 2 studies differing only in number of sessions and 5 studies differing only in adjunctive treatment.
Additionally, I predict that at the completion of our study, despite the higher doses given per treatment in the experimental accelerated, hypofractionated RT arm, there will be no increased toxicity with this regimen.
This pivotal trial is the largest study conducted of renal artery denervation as a treatment for resistant hypertension and the most rigorously designed, including blinding and a sham treatment in the control arm.
Although both study groups showed a statistically significant decrease at six months compared with baseline -LRB--14.1 mmHg for renal denervation compared to -11.7 mmHg for the sham treatment control), the difference of -2.29 mmHg in office systolic blood pressure between the two arms was not significant.
Specifically, Delfraissy says if the monkey studies and the finer analysis of patient samples have positive results, perhaps the standard of care should include favipiravir as part of the control arm in studies of ZMapp and other experimental treatments.
Forty patients assigned to surgery dropped out of the study before treatment, while only four assigned to the TAVR arm dropped out.
The rates of treatment discontinuations and serious adverse events were low and similar in the two arms of both studies.
«Despite the limitations of a single arm, non-randomized study, we infer from these data that Interferon ß - 1a treatment is worth further consideration for the treatment of Ebola virus disease,» said Dr. Fish, who is also a Professor in the Department of Immunology at the University of Toronto, noting that the decision to undertake the clinical trial was based on previous preliminary scientific data, and on the fact that no currently approved antivirals exist to treat Ebola.
The study, entitled, «Interferon ß - 1a for the treatment of Ebola virus disease: A historically controlled, single - arm proof of concept trial,» published in PLoS One, a high - impact journal which is freely and immediately available to everyone.
«This study arms us with information that may help us push toward shorter antibiotic treatment courses and minimizing the use of broad - spectrum antibiotics.»
Multiple logistic regression analysis was used to estimate the odds of pregnancy during the study by treatment arm (odds ratios [ORs] are presented with 95 % confidence intervals).
Although many treatment studies do not report treatment attendance figures, these results compare favorably with those of the Treatment for Adolescents With Depression Study, a well - known, highly controlled investigation in which approximately 82 % of participants remained in their assigned treatment arm through 12 weeks of acute treatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in eachtreatment studies do not report treatment attendance figures, these results compare favorably with those of the Treatment for Adolescents With Depression Study, a well - known, highly controlled investigation in which approximately 82 % of participants remained in their assigned treatment arm through 12 weeks of acute treatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in eachtreatment attendance figures, these results compare favorably with those of the Treatment for Adolescents With Depression Study, a well - known, highly controlled investigation in which approximately 82 % of participants remained in their assigned treatment arm through 12 weeks of acute treatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in eachTreatment for Adolescents With Depression Study, a well - known, highly controlled investigation in which approximately 82 % of participants remained in their assigned treatment arm through 12 weeks of acute treatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in eachtreatment arm through 12 weeks of acute treatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in eachtreatment.50 There is potential for MF - PEP to be cost - effective since clinician time is maximized by having multiple participants in each session.
As for limitations, this study relied on self - report to obtain cost data, but this was regarded as acceptable against the background that studies have demonstrated high convergence between registry data and health economic estimates collected through self - report.37 A second limitation was that we did not include a treatment arm of face - to - face CBT, which constitutes a highly important comparison treatment.
Such a modification is seen in the introduction of an open verum treatment arm, in which participants are certain to receive the study drug.
Comparisons possible were: 3 studies with treatment arms differing only in the approach (group, individual or self - administered), 2 studies differing only in number of sessions and 5 studies differing only in adjunctive treatment.
Children randomized to one of the two treatment arms of the Bucharest Early Intervention Project (FCG or CAUG) were considered to have remained in those treatments across the time period of the study.
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