The changes included reductions in the use and dose of radiation therapy and chemotherapy drugs called anthracyclines for
treatment of acute lymphoblastic leukemia (ALL), Hodgkin lymphoma and Wilms tumor, a cancer of the kidneys.
This study included 68 childhood cancer survivors who had received cranial irradiation, intrathecal chemotherapy or both for
treatment of acute lymphoblastic leukemia (ALL) or brain tumors.
Not exact matches
In March, the U.S. Food and Drug Administration (FDA) approved BLINCYTO for the
treatment of adults and children with B - cell precursor
acute lymphoblastic leukemia in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1 percent.
Current
treatments for
acute lymphoblastic leukemia (ALL), an aggressive form
of blood cancer, include conventional chemotherapy drugs that inhibit DNA synthesis.
Noelle Frey, MD, an assistant professor
of Hematology - Oncology, will present results in 27 adult patients with
acute lymphoblastic leukemia (ALL), identifying an optimal dose and infusion regimen that should improve
treatment response while reducing potential for side effects.
His group was the first to publish findings
of dramatic molecular remissions in patients with chemorefractory
acute lymphoblastic leukemia following
treatment with autologous CD19 - targeted T cells.
The FDA approves Blincyto (blinatumomab) for use in the
treatment of B cell
acute lymphoblastic leukemia (ALL).
Herbert OettgenCRI CONNECTIONCVC MEMBERSCIENTIFIC ADVISOR reports the first
treatment of patients with
acute lymphoblastic leukemia with L - asparaginase.
In 2014, the FDA approved Amgen's BLINCYTO ® (blinatumumab), the first BiTE ® therapy to receive FDA approval, for the
treatment of Philadelphia chromosome - negative relapsed or refractory B - cell precursor
acute lymphoblastic leukemia, a rare and rapidly progressing cancer
of the blood and bone marrow.
Endari, the first new
treatment for patients with sickle cell disease in almost 20 years, Genentech's Hemlibra, the first - ever non-blood product to treat patients with hemophilia A with inhibitors, Actemra, the first
treatment for adults diagnosed with giant cell arteritis, BioMarin's Brineura, the first
treatment for a form
of Batten disease, Benznidazole, the first U.S.
treatment for Chagas disease, Novartis» Kymriah to treat certain children and young adults with B - cell
acute lymphoblastic leukemia, which is also the first gene therapy to become available in the United States, are some
of the drugs that received the FDA's stamp
of approval in 2017.
Other CAR T - cell therapies approved in 2017 include tisagenlecleucel for the
treatment of children and young adults up to 25 years
of age with relapsed or refractory B - cell precursor
acute lymphoblastic leukemia and axicabtagene ciloleucil (aci - cel; Yescarta) for adults with relapsed or refractory DLBCL.
A team
of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges
of treatment for
acute lymphoblastic leukemia, among the most common types
of cancer in children, and has the potential to help doctors personalize drug doses.
Introduction: The level
of minimal residual disease (MRD) in marrow predicts outcome and guides
treatment in childhood
acute lymphoblastic leukemia (ALL) but accurate prediction depends on accurate measurement.
Lead study author Dr. Daniel Lacorazza noted that «
acute lymphoblastic leukemia is a type
of cancer
of the white blood cells common in children... there is about an 80 percent cure rate, but some children don't respond to
treatment.