Sentences with phrase «treatment of brain metastases»
Several tests in cultured cells indicated that ganciclovir would cause the death of HSV - TK - expressing stem cells, and testing in the mouse model confirmed that administration of the drug after successful treatment of brain metastases successfully eliminated therapeutic stem cells that also expressed HSV - TK.
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«Viable treatment options for brain metastases are still an unmet need,» said Hong Zhao, M.D., Ph.D., assistant professor of systems medicine and bioengineering at Houston Methodist Research Institute and co-corresponding author.
«We found genetic alterations in brain metastases that could affect treatment decisions in more than half of the patients in our study,» Dr Brastianos will say.
Approximately eight to ten percent of cancer patients will develop brain metastases, and treatment options are limited.
«Genetic screening of brain metastases could reveal new targets for treatment.»
Thus, based on the robust findings from the current study and until proven otherwise, WBRT may still have an important role for treatment of patients who are not in this specific disease category (i.e., 1 - 3 brain metastases).
Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after SRS, yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial.
While neither a drug that targets HER3 nor one that interferes with the interaction between HER2 and HER3 were able to slow the growth of brain metastases, combined treatment with both an anti-HER2 and an anti-HER3 drug significantly slowed tumor growth.
After confirming in mouse models that cells from HER2 - positive breast cancers became resistant to anti-HER2 treatment when implanted into the brain but not into other tissues, the investigators found that HER3 is overexpressed in brain metastases of HER2 - positive breast cancers from both mice and human patients.
«Stem - cell - based therapy promising for treatment of breast cancer metastases in the brain.»
Faculty in the Brain and Spinal Tumor Program focus on clinical research and treatment of primary brain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain manageBrain and Spinal Tumor Program focus on clinical research and treatment of primary brain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain managebrain tumors, neoplastic meningitis, brain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain managebrain metastases, epidural cord compression, neurotoxicities, anticancer agents, and cancer pain management.
Undergoing immunotherapy within a month of stereotactic radiosurgery resulted in an improved response to treatment for patients with melanoma brain metastases.
Dr. Anders, a native of Burlington, N.C., an assistant professor in the University of North Carolina at Chapel Hill School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center, was chosen for her work on the identification of the prognosis and treatment of breast cancer brain metastases.