Type of Study: Randomized controlled
trial Number of Participants: Adults: 16 to 42 years, Children: 1 to 23 months
Type of Study: Randomized controlled
trial Number of Participants: 63 Intervention, 49 Methadone - only
Type of Study: Randomized controlled
trial Number of Participants: 110 families (mother, stepfather, and child [ren]-RRB-
Type of Study: Randomized controlled
trial Number of Participants: 38 children and their families
Type of Study: Randomized controlled
trial Number of Participants: 634 families provided pre and posttest data.
Type of Study: Randomized controlled
trial Number of Participants: Control group: 275, Intervention group: 607
Type of Study: Randomized controlled
trial Number of Participants: 114 (demographic breakdown below reflects initial 120 participants)
Type of Study: Randomized controlled
trial Number of Participants: 1139 allocated to treatment; 627 seen in this follow - up
Type of Study: Randomized controlled
trial Number of Participants: 37 adolescents and their families
Type of Study: Randomized controlled
trial Number of Participants: 120 children and 113 parents (7 parents had 2 children enrolled in the study)
Type of Study: Randomized controlled
trial Number of Participants: 93, plus 48 children not in foster care
Not exact matches
OCE said it found evidence that Collins sent emails to shareholders with background information about the company, including information about the
number of clinical
trial participants and timeline, that were not disclosed publicly.
Dr. Vaillancourt speculated that his team's free water approach could make clinical
trials less expensive by reducing the
number of participants they would need to enroll.
More clinical
trials with larger
numbers of participants are needed to tease out the most effective cannabis - based therapies.
«We have shown that a large
number of study
participants are routinely exposed to the risks
of trial participation without the benefits that sharing and publishing results would have for patients in the future.
Yale enrolled the largest
number of participants at any one site (84
of 790) for these double - blind, placebo - controlled
trials that investigated the efficacy
of testosterone gel for multiple outcomes, including sexual function, physical function, and vitality.
One way to correct for the gaps the gold standard leaves in our knowledge is the «N
of 1»
trial, where the
number of participants (N) is one instead
of hundreds or thousands
of volunteers.
In line with other
trials of a similar nature, drop - out rates were around 20 % and around a third
of participants in both groups did not attend the minimum
number of therapy sessions.
The study was the first randomized - controlled
trial to examine the potential benefits
of the low fat diet on the management
of MS.. The study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures
of MS.. But while the
number of trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies
of the diet.
As a result
of a 2007 law, within 1 year
of the completion
of a
trial, drug companies must also submit summary results that include information such as the
number of participants, their age and gender, outcomes, and adverse events.
This
trial also looked at the effects
of corticosteroids on HIV - positive people, but the small
number of included
participants meant that the review authors were unsure if the benefits in terms
of a reduction
of death was preserved in this group
of participants.
In a presentation
of early clinical
trial data to the 20th Annual Scientific Meeting
of the Society for Neuro - Oncology, physician scientists from the University
of New Mexico Comprehensive Cancer Center reported that a large
number of study
participants responded well to the drug combination.
Importantly this new vaccine has a better safety profile than traditional injection allergen immunotherapy, however the
trial participants experienced a high frequency
of local side effects which were unexpected and warrants further investigation in larger
numbers of patients.»
We also performed subgroup meta - analyses by type
of prevention (primary v secondary: in this study,
trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention
trials, and
trials involving patients with cardiovascular disease were classified as secondary prevention
trials), type
of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type
of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type
of outcome in each supplement, type
of study design (randomised, double blind, placebo controlled
trial v open label, randomised controlled
trial), methodological quality (high v low), duration
of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider
of supplements (pharmaceutical industry v not pharmaceutical industry), type
of control (placebo v no placebo),
number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.
The article by Mansukhani et al1 in this issue
of JAMA Surgery reveals that, despite the introduction
of the National Institutes
of Health Revitalization Act
of 1993 to ensure that female
participants were included in clinical
trials, males and females currently are not included in surgical clinical research in equal
numbers.
As the amount
of perceived odors varied between the
participants, the regressors were weighted in relation to the total
number of trials for each
participant and condition.
The results
of a seven - day
trial showed the curcumin - supplemented
participants had better lipid profile
numbers.
The popularity
of the AKC Hunt Tests continues to grow even though the
number of participants in the AKC Field
Trials continues to decline.
Type
of Study: Randomized controlled
trial (block randomized within each
of three stratification groups)
Number of Participants: 98
Type
of Study: Randomized controlled
trial; 2 (treatment condition) x 4 (time) repeated - measures intent - to - treat randomized design
Number of Participants: 224
A study
of individual cognitive therapy for bipolar disorder showed positive outcomes at 1 - year follow - up, but the benefits were reduced over time, suggesting the need for booster sessions to sustain the gains.19 As with many forms
of therapy, CBT has been found to be more successful in reducing relapse in the depressive pole compared with the manic pole.30 A large randomised
trial of CBT showed no difference between CBT and treatment as usual, when all
participants were included in the analyses.31 However, results
of a post-hoc analysis suggested that CBT was effective for
participants who reported fewer than 12 prior episodes
of illness and were not acutely unwell when therapy began;
numbers of episodes
of mania rather than depression seemed to predict treatment response.32 Such data can help guide the clinical application
of CBT for bipolar patients.
Type
of Study: Randomized controlled
trial comparing two versions
of the intervention
Number of Participants: 42 parents
Type
of Study: Clustered randomized controlled
trial (randomization at the school level)
Number of Participants: 286
Type
of Study: Randomized controlled
trial (secondary data analysis)
Number of Participants: 331 children and their parents
Type
of Study: Randomized controlled
trial using stratification by child age
Number of Participants: 26
Type
of Study: Randomized controlled
trial using matched pairs
Number of Participants: 50 families in each condition
Type
of Study: Partially randomized controlled
trial (3
of 11 groups were randomized)
Number of Participants: 69
Type
of Study: Clustered randomized controlled
trial (randomization at the building level)
Number of Participants: 246
Type
of Study: Randomized controlled
trial with matching (secondary analysis)
Number of Participants: 25
Type
of Study: Randomized controlled
trial with some adjustment (see summary)
Number of Participants: 14
Type
of Study: Clustered randomized controlled
trial (randomization at the classroom level)
Number of Participants: 57
Type
of Study: Randomized controlled
trial comparing 3 and 9 month versions
of the program
Number of Participants: 154 families
Cuijpers (2003) indicates that the low base rate
of depression in children and adolescents and small effect sizes for universal
trials, make it difficult to detect effects without a substantial
number of participants.