Sentences with phrase «trial of more»

In 1998, Congress mandated an evaluation of Head Start, called the Head Start Impact Study, a randomized trial of more than 4,000 children, ages 3 and 4, newly entering the Head Start program.

To test the efficacy of an intervention including buprenorphine, a medication that reduces opioid cravings and helps to prevent relapse to opioid use, the Yale team — lead by D'Onofrio and Dr. David Fiellin, professor of medicine — conducted a randomized trial of more than 300 opioid - dependent individuals in an urban teaching hospital.

Initial results were announced from the Trial Assigning IndividuaLized Options for Treatment (Rx), or TAILORx, a multi-center prospectively conducted trial of more than 10,000 women with early stage breast cancer sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, and led by the ECOG - ACRIN Cancer Research Group (ECOG - ACRIN) with support from Genomic Health, Inc..

A clinical trial of more than 10,000 heart attack patients reported today supports a novel way to protect them from a stroke or a second attack: with drugs that stop inflammation.

A clinical trial of more than 10,000 heart attack patients has confirmed cardiologists» long - standing suspicion that inflammation helps trigger heart attacks.

Through a randomized trial of more than 3,000 first - time mothers, the research team out of the University of Birmingham in England studied the effects of two laboring positions.

In a clinical trial of more than 600 participants, Empliciti, when used with cancer drug Revlimid and steroid dexamethasone was better at delaying when the cancer worsened than just the two drugs alone.

The justice ministry announced last week that the trials of more than 1,600 suspects were scheduled to begin from October 9.

Writing in The Lancet, four flu experts describe blending data from nine clinical trials of more than 4000 patients to assess Tamiflu.

Provincial court judges handle bail hearings, preliminary hearings, trials involving youth, all trials of less serious offences and many trials of more serious offences where people choose a trial in the provincial court.

Not exact matches

During the session, a trio of experts discussed the opportunities and challenges of a more globalized world, including cross-border clinical trials, the spread of disease and emerging pathogens and managing supply chains.

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

The trial made embarrassing national headlines for the once - rising Democratic star, who was accused of seeking more than $ 900,000 from two wealthy supporters to conceal his pregnant mistress, Rielle Hunter, from voters during his unsuccessful run for the Democratic presidential nomination in 2008.

The gesture is fitting — Bouchard's transformation of Alimentation Couche - Tard from a single convenience store into a $ 35 - billion retail empire is one of the country's more successful business stories of the past 40 years — but 2016 has not been without its trials.

The Chinese government financed nationwide studies into cockroaches» medical value that, after more than two decades of laboratory investigation and clinical trials, had discovered or confirmed dozens of disease - fighting proteins and biochemical compounds with huge potential value in medicine.

But until some of the current trials turn into more compelling commercial services, the value of the high bands remains unproven.

There are more than 80 immune - related cancer therapies currently in clinical trials, fueled by many billions of dollars in pharmaceutical investment from the likes of Bristol - Myers Squibb bmy, Merck mrk, Pfizer pfe, and dozens of biotechs.

Creese said they've seen more than 90 % suppression in trials of their genetically engineered mosquitoes.

A 2013 review of 29 trials which involved more than 11,300 people found «no consistent effect of vitamin C... on the duration or severity of colds.»

Still, despite what he feels is a weak case against him, he thinks the odds are he'll be found guilty, at least during this first trial; Japan, which has a more than 99 % conviction rate, is also one of a few countries that allows prosecutors to appeal an acquittal twice.

With its new features, Medium's main target appears to be blog - hosting or content - management providers like WordPress, whose open - source software powers more than 20 % of the web, including sites like Fortune and TechCrunch (Fortune is partnering with Medium for a trial project, as is Money magazine, both of which are owned by Time Inc.).

Among them: «a lack of data standards in treating cancer, lack of data sharing in the research and development enterprise, lack of patient input and participation in clinical trials,» and more.

The trial took more than a month and jury deliberations stretched out over the course of this week.

Of course, you can learn much more about Airbnb's history, trials, tribulations and triumph in my new book, The Airbnb Story: How Three Ordinary Guys Disrupted an Industry, Made Billions... and Created Plenty of ControversOf course, you can learn much more about Airbnb's history, trials, tribulations and triumph in my new book, The Airbnb Story: How Three Ordinary Guys Disrupted an Industry, Made Billions... and Created Plenty of Controversof Controversy.

Though Canada's provincial revenue volatility troubles have much more to do with resource royalties than personal income taxes, Alberta and Newfoundland could perhaps learn a thing or two from the trials and tribulations south of the border — and how the smartest states are trying to fix the problem.

Oxitec has conducted similar trials in Brazil, Panama, and the Cayman Islands, reducing the populations of Aedes aegypti more than 90 percent, the company previously reported.

For example, for anyone who is familiar with my other writings you may recall that I am a trial attorney who has tried hundreds of cases in my career and litigated thousands more.

Horizon Power will trial a new method of charging residents and businesses in Port Hedland for electricity, with the aim of giving customers more control over their power usage.

In the company blog, Telsa referred to Organ as having «a long track record of extorting money for meritless claims» and said that the company «would rather spend more on a trial and clear its name than settle with the plaintiff.»

And while such devices aren't yet a common part of standard healthcare, more and more research and clinical trials are underway to demonstrate the usefulness of continuous RPM, especially for things like chronic illnesses.

Through trial and error I've learned that there's one simple and foolproof way to get rid of a bad customer without taking on emotional baggage: Raise your price to more than the customer will pay.

How well they withstood those trials and how quickly they revived depended, perhaps more than anything, on the depth and integrity of their reputations.

Amgen unveiled some promising news during the American Heart Association's annual meeting involving its next - gen cholesterol - busting medication Repatha, which has been shown to significantly reduce the level of «bad» cholesterol in patients, announcing that more than 60 % of patients who were receiving the therapy in a trial had a reduction in arterial plaque.

According to PhRMA, there are more than a dozen experimental treatments that are still in phase 3, the latest stage of clinical trials before companies present their data to the FDA.

More than 4,000 individuals have voluntarily received the rVSV - ZEBOV vaccine as part of the Phase 3 trial which began in March, according to Merck.

Now that the barrier of editing genes in the hospital setting has been broken, these companies and more have pipelines of gene - editing innovation coming to a hospital near you in the next few years, as clinical trials are approved and new ways to cure formerly incurable diseases go mainstream in our lifetimes.

Today, more than 15,000 people have taken Lactagen, an over-the-counter derivative of the formula Ritter cooked up, and his company, Ritter Pharmaceuticals, is about to launch trials for a prescription drug to treat lactose intolerance — an endeavor that can cost upward of $ 50 million before the FDA gives its OK.

The company has moved from research on rats to the cusp of human trials in less than five years at a cost of less than $ 5 million, a process that can often take twice that long and cost many times more.

And while the first phase of the trial was at times grueling for members of the jury - several breaking into tears as they listened to descriptions of the chaos near the Marathon finish line - the second phase could be even more so.

Parker was acquitted in the rape case more than a decade ago and Celestin had his sexual assault conviction overturned on appeal (a higher court deemed his trial attorney ineffective), but the two men have come under fire once again as the media reports troubling details from the case, which included accusations that Parker and Celestin, then both 19, had sex with a Penn State freshman while she was unconscious after a night of heavy drinking.

When Jedd Wolchok, a cancer doctor and immunologist leading a Yervoy trial at Memorial Sloan Kettering, examined a melanoma patient's scan 12 weeks after he'd received his course of treatment, the results were utterly disappointing — just like those of any other metastatic patient in the final throes of the disease: The tumors had gotten bigger, and there were more of them.

The case was yet more evidence that both the clinical trial doctors and the drug's developers would have to be more patient in assessing this new type of therapy.

Cowen analyst Colby Synesael agrees that Comcast's initial wireless foray appears to be more of a trial at this stage.

Paris (AFP)- Carlos the Jackal, the perpetrator of headline - grabbing attacks in the 1970s and early 1980s, goes on trial in France on Monday for the deadly bombing of a Paris shop more than 40 years ago.

In fact, one of Marathon's clinical trials that the FDA used as part of its decision - making process was conducted more than 20 years ago, saving the firm plenty of study costs.

Connor Schell, executive producer of ESPN Films, told reporters on a conference call earlier this week that, when he first discussed the project that became Made in America with the director Edelman more than two years ago, they had no idea to what extent the Simpson trial would reassert itself into American popular culture after two decades — not to mention the surge in popularity of the true crime genre, as seen recently with documentary series like Netflix's Making a Murderer and HBO's The Jinx.

If those trials are successful, Domino's could expand the service to more of its 2,000 - plus stores worldwide.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

That test saw the newspaper receive more than 700 bitcoin donations over a 24 - hour trial period in support of the non-profit Taproot foundation, which offers pro-bono service work to organisations tackling social problems.

Finally the amount of capital needed to take a drug to FDA trials could be enormously expensive, at least 10x more than startup costs at an electron - based company.