Sentences with phrase «trial of zinc»

Randomized, controlled trial of zinc supplementation in malnourished Bangladeshi children with acute diarrhea.

Birmingham CL, Goldner EM, Bakan R. Controlled trial of zinc supplementation in anorexia nervosa.

A double - blind trial of zinc supplementation in pregnancy.

A trial of zinc supplementation in young rural Gambian children.

Controlled trial of zinc supplementation during recovery from malnutrition: effects on growth and immune function

In addition, results from a pooled analysis of randomized controlled trials of zinc supplementation in developing countries suggest that zinc helps reduce the duration and severity of diarrhea in zinc - deficient or otherwise malnourished children [62].

Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«However, while these encouraging results in mice mean that the zinc finger looks like a good candidate to take forward to human trials, we still need to do a lot of work first to answer important questions around the safety of the intervention, whether repeat treatments are effective, whether there might be longer - term side effects, and whether we can extend and increase the benefits beyond six months.

Those children who took zinc were less likely to suffer a bout of diarrhea, and when the researchers looked at growth differences, they saw that children who were given zinc were slightly taller by the end of the trials compared to those who did not.

The trial is using a form of DNA scissors called zinc finger nucleases (ZFNs).

Randomized controlled trials showed that zinc supplementation can reduce the severity of morbidity from a number of common childhood infections, including diarrhea, pneumonia, and possibly malaria, by one - third.

When the trial ended, in 2001, AREDS showed that a specific formula of nutritional supplements containing high doses of antioxidants and zinc could slow the disease in those who have intermediate AMD and those with advanced AMD in only one eye.

A major clinical trial sponsored by the National Eye Institute showed that a daily supplement of 500 milligrams of vitamin C, 400 IU of vitamin E, 15 milligrams of beta - carotene, 80 milligrams of zinc, and 2 milligrams of copper reduced the risk of moderate or severe AMD - related vision loss by up to 25 percent.

Barnett JB, Dao MC, Hamer DH, et al: Effect of Zinc Supplementation on Serum Zinc Concentration and T Cell Proliferation in Nursing Home Elderly: A Randomized, Double - Blind, Placebo - Controlled Trial.

Another double - blind clinical trial published in the British Journal of Dermatology in 1977, discovered that zinc supplements were equally effective as oxytetracycline, an oral antibiotic sometimes prescribed for treating acne.

Two other small clinical trials evaluated the effects of supplementation with 200 mg zinc sulfate (providing 45 mg zinc) for 2 years in subjects with drusen or macular degeneration.

In a randomized, double - blind, placebo - controlled clinical trial, 50 subjects (within 24 hours of developing the common cold) took a zinc acetate lozenge (13.3 mg zinc) or placebo every 2 — 3 wakeful hours.

Brown KH, Allen LH, Peerson J. Zinc supplementation and children's growth: a meta - analysis of intervention trials.

Neither zinc gluconate nor zinc acetate lozenges affected the duration or severity of cold symptoms in 281 subjects with natural (not experimentally induced) colds in another trial [68].

In another clinical trial involving 273 participants with experimentally induced colds, zinc gluconate lozenges (providing 13.3 mg zinc) significantly reduced the duration of illness compared with placebo but had no effect on symptom severity [68].

Siahbazi S. Effect of zinc sulfate supplementation on premenstrual syndrome and health - related quality of life: Clinical randomized controlled trial.

Roth, D. E., Richard, S. A., and Black, R. E. Zinc supplementation for the prevention of acute lower respiratory infection in children in developing countries: meta - analysis and meta - regression of randomized trials.

Sazawal, S., Black, R. E., Jalla, S., Mazumdar, S., Sinha, A., and Bhan, M. K. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double - blind, controlled trial.

Effect of routine zinc supplementation on pneumonia in children aged 6 months to 3 years: randomised controlled trial in an urban slum.

Tielsch, J. M., Khatry, S. K., Stoltzfus, R. J., Katz, J., LeClerq, S. C., Adhikari, R., Mullany, L. C., Black, R., and Shresta, S. Effect of daily zinc supplementation on child mortality in southern Nepal: a community - based, cluster randomised, placebo - controlled trial.

A community - based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development.

Hakimi, M., Dibley, M., Surjono, A., and Nurdiati, D. Impact of vitamin A and zinc supplementation on puerperal sepsis: a randomized controlled trial in rural Indonesia.

Bobat, R., Coovadia, H., Stephen, C., Naidoo, K. L., McKerrow, N., Black, R. E., and Moss, W. J. Safety and efficacy of zinc supplementation for children with HIV - 1 infection in South Africa: a randomised double - blind placebo - controlled trial.

Merialdi, M., Caulfield, L. E., Zavaleta, N., Figueroa, A., Dominici, F., and Dipietro, J. A. Randomized controlled trial of prenatal zinc supplementation and the development of fetal heart rate.

Prevention of diarrhea and pneumonia by zinc supplementation in children in developing countries: pooled analysis of randomized controlled trials.

Randomized, community - based trial of the effect of zinc supplementation, with and without other micronutrients, on the duration of persistent childhood diarrhea in Lima, Peru.

A double - blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mexico.

Effect of zinc supplementation started during diarrhoea on morbidity and mortality in Bangladeshi children: community randomised trial.

Sazawal, S., Black, R. E., Ramsan, M., Chwaya, H. M., Dutta, A., Dhingra, U., Stoltzfus, R. J., Othman, M. K., and Kabole, F. M. Effect of zinc supplementation on mortality in children aged 1 - 48 months: a community - based randomised placebo - controlled trial.

Gulani, A., Bhatnagar, S., and Sachdev, H. P. Neonatal zinc supplementation for prevention of mortality and morbidity in breastfed low birth weight infants: systematic review of randomized controlled trials.

Wuehler, S. E., Sempertegui, F., and Brown, K. H. Dose - response trial of prophylactic zinc supplements, with or without copper, in young Ecuadorian children at risk of zinc deficiency.

Mathew, J. L. Zinc supplementation for prevention or treatment of childhood pneumonia: a systematic review of randomized controlled trials.

Sazawal, S., Black, R. E., Bhan, M. K., Jalla, S., Sinha, A., and Bhandari, N. Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea — a community - based, double - blind, controlled trial.

Rico, J. A., Kordas, K., Lopez, P., Rosado, J. L., Vargas, G. G., Ronquillo, D., and Stoltzfus, R. J. Efficacy of iron and / or zinc supplementation on cognitive performance of lead - exposed Mexican schoolchildren: a randomized, placebo - controlled trial.

Effect of zinc supplementation on malaria and other causes of morbidity in west African children: randomised double blind placebo controlled trial.

A controlled trial on utility of oral zinc supplementation in acute dehydrating diarrhea in infants.

A systematic review of effect of prenatal zinc supplementation on birthweight: meta - analysis of 17 randomized controlled trials.

Merialdi, M., Caulfield, L. E., Zavaleta, N., Figueroa, A., Costigan, K. A., Dominici, F., and Dipietro, J. A. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.

Although there were no significant differences in teacher or parent rating scores between the zinc and placebo group in phase 1 or 2 of the trial, data from phase three showed that the group receiving zinc 15 mg twice a day required a 37 % lower dosage of AMPH when compared to placebo [18,48].

Authors speculated that this trial was unable to replicate previous response rates because prior studies were done in areas of high zinc deficiency.

Zumthor is the only foreign architect to participate, with two projects, [citation needed] the Memorial in Memory of the Victims of the Witch Trials in Varanger, a collaboration with Louise Bourgeois (2011), [4] and a rest area / museum on the site of the abandoned Allmannajuvet zinc mines, in operation from 1882 to 1898, in Norway (2016).

[2] In 1999, Zumthor was selected as the only foreign architect to participate in Norway's National Tourist Routes Project, with two projects, the Memorial in Memory of the Victims of the Witch Trials in Varanger, a collaboration with Louise Bourgeois (completed in 2010), and a rest area / museum on the site of an abandoned zinc mine.