Sentences with phrase «trial research involving»

The Bringing Baby Home program has been evaluated through random clinical trial research involving 159 families.

Not exact matches

The review of three trials, involving 233 women, found there has not been enough research done to show the effects of castor oil on ripening the cervix or inducing labour or compare it to other methods of induction.

Ministers said this could be something simple like updating CV's or researching the availability of childcare, but could also involved skills training or trial work.

Science and Technology — Subject: Clinical trials Witness (es): Professor Karol Sikora, Medical Director of Cancer Partners UK and Dean, University of Buckingham Medical School and Simon Denegri, NIHR National Director for Public Participation and Engagement in Research and Chair, INVOLVE; Tracey Brown, Managing Director, Sense About Science and Dr Helen Jamison, Deputy Director, Science Media Centre; Sir Kent Woods, Chief Executive,, Dr Janet Wisely, Chief Executive, Health Research Authority, Bill Davidson, Acting Deputy Director and Head of Research Standards and Support, Department of Health and Peter Knight, Deputy Director, Head of Research Information and Intelligence, Department of Health Location: Room 8, Palace of Westminster

This process, which will be the focus of much of the group's forthcoming research, will necessarily involve extensive trials.

Many physician scientists involved in clinical trials, epidemiology, and health services research are trained through master's programs completed either during or (more frequently) after medical school, with degrees in clinical epidemiology, biostatistics, public health, or health services and outcomes research.

The trial, a phase 3 study involving major cancer research institutions in Europe, the United States, Australia and Japan, enrolled 800 patients with metastatic colorectal cancer that was progressing despite previous treatment.

That's because a trial like this one is almost without precedent in modern medical research: It involves giving children a vaccine that is almost certain not to benefit them, and that might harm them, all to protect other children from an unlikely scenario — a large - scale anthrax attack.

The trial of research on ANGPTL3 as a potential target for atherosclerosis prevention began over a decade ago when scientists reported on two cases of familial hypolipidemia, a rare inherited condition involving abnormally low blood levels of cholesterol and triglycerides.

In the next stage of this research involving clinical trials, the scientists intend to test the effectiveness of these reversible monoamine oxidase A inhibitors in the treatment of postpartum depression.

For the investigators involved in the research, the results, though obtained in a relatively small, phase 1 trial, are compelling.

«For the first time, we can predict the outcomes of modifying multiple genes involved in lignin biosynthesis, rather than working with a single gene at a time through trial and error, which is a tedious and time - consuming process,» says Jack Wang, assistant professor in NC State's College of Natural Resources and lead author of a paper about the research in Nature Communications.

Chair of the Congress and President of ECCO, Professor Peter Naredi, from the Sahlgrenska Academy, University of Gothenburg, Sweden, who was not involved with the research, commented: «For rare cancer types it is difficult to evaluate new treatments in normal sized trials.

The episode highlights a tricky dilemma for companies and research teams involved in deep brain stimulation (DBS) research: If trial participants want to keep their implants, who will take responsibility — and pay — for their ongoing care?

«Because of this stress, many patients will drop out of treatment,» explains Daniel Zuj, a research psychologist at the University of Tasmania in Launceston, Australia, who is not involved in the MDMA trials.

The next phase of the Penn State research will involve raising heritage birds in a silvopasture system where they will be able to forage and eat natural feedstuffs as they find them outdoors, instead of predominantly commercial turkey feed in a pen trial.

Commenting on the study, Dr Andres Poveda, Head of the Gynecological Oncology Clinic at Fundación Instituto Valenciano de Oncología, Valencia, Spain, who was not involved in the research, said the CIRCCa study is the second recent trial to show the benefit of adding an antiangiogenic drug to chemotherapy in cervical cancer.

But these trials involve cells that were originally created using animal products for research.

This study is part of Phase one of the RECOVER Program, a multi-phase project, involving 10 intensive care units across Canada, co-led by Drs. Margaret Herridge, Scientist at the Toronto General Research Institute, and Cameron, in collaboration with the Canadian Critical Care Trials Group.

This investigator - initiated phase II trial, called TOPARP - A, was led by researchers at The Institute of Cancer Research, London and The Royal Marsden NHS Foundation Trust, and also involved several other institutions in the UK.

Part of the problem is that trials involving vitamin D and calcium are inconsistent — they test different doses for varying lengths of time in diverse populations, which «makes it extra tricky when you try to put them all together and come up with a final analysis,» says Erin LeBlanc, an endocrinologist at the Kaiser Permanente Center for Health Research in Portland, Ore..

Alley and his team presented data from KEYNOTE - 028, an ongoing trial involving 13 different research sites in six different countries all looking at the effect of pembrolizumab on patients with advanced malignancies, including malignant pleural mesothelioma.

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.»

Purpose: The development of the UNC Immuno - Oncology Patient Centered Translational Research (IMPACT) Biorepository involves the collection of tumor tissue and blood, as well as data (e.g., demographic, clinical, questionnaire) from patients attending Oncology Clinics at UNC Hospital and undergoing immune therapy through participation in a Merck IT trial at UNC.

A major theme is translational research involving the rapid early - stage development and assessment of new vaccines in clinical trials.

Ongoing research involves the evaluation of immune checkpoint inhibition in collaboration with the Ludwig / CRI CVC trials network and the pharmaceutical industry.

My translational research interests involve clinical trials evaluating targeted biologic agents, particularly early phase trials with targeted antibodies.

We believe our team also has a responsibility to be actively involved in cardiovascular research and vascular and heart clinical trials.

A team of Hopkins researchers has long been involved in immunotherapy research, including on pioneering clinical trials.

His research interests have included the immunogenetics of diabetes, the biology of tumour - associated antigens and cell adhesion molecules, and ethical aspects of the design of trials involving human subjects.

A research team led by Gianluca Maddalo (KTH), involving several researchers at SciLifeLab, has discovered that melanoma resistance against BRAF and Hsp90 inhibitors can be overcome by implementing the current BRAF / MEK inhibitors therapy with a CDK2 inhibitor, dinaciclib, already used in clinical trials.

The objective of the fellowship is to provide an in - depth clinical research training experience at a premier medical center with expertise and significant clinical volume in the area of biochemical genetics, including lysosomal storage diseases, as well as in therapeutics and clinical trials involving patients with these and other metabolic diseases and, thereby, to increase the number of medical geneticists with interest, knowledge, and expertise in this area.

A research team involving Adil Mardinoglu and Mathias Uhlén at KTH Royal Institute of Technology / SciLifeLab are planning a clinical trial of a new treatment for nonalcoholic fatty liver disease and type 2 diabetes.

Later, in addition to his medical practice, Dr. Wilderman was getting involved with clinical trials and medical research.

A clinical trial is a research study that involves people who volunteer to take part in a study.

Translational research is a high - risk, iterative phase of the drug development pipeline that involves a lot of trial and error to assess if the drug...

In a substudy, review outcomes were also compared across different types of clinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanresearch, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanResearch, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanResearch and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanresearch focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified humanresearch; and (7) use of deidentified human tissue.

This includes funding a paediatric Clinical Trials Unit and a biobank, which collects tissue and blood samples generously donated by young patients involved in research.

Immune responses of patients could point way forward for future vaccines.In the latest study, researchers involved with the trial at Mahidol University in Bangkok and the U.S. Military HIV Research Program in Washington DC assembled a team to scour the blood of trial participants for immune indicators that differed between 41 people who received the vaccine and contracted HIV and 205 participants who did not become infected.

Recently, iBET became the coordinator of a research unit funded by FCT, iNOVA4Health, a translational medicine program organising the efforts of biomedical researchers involved in biological understanding of disease, lead compounds and biopharmaceuticals «pre-discovery», technological scientists involved in «preclinical development», and clinicians involved in «early clinical and first in man clinical trials» from institutions within NOVA University of Lisbon.

In addition to a strong interest in research he has been involved with a number of clinical trials and first in man trials, several as the principal investigator for Australia.

In the new study, a research team at the Rakai Health Sciences Program in Uganda — in collaboration with researchers from the Johns Hopkins University Bloomberg School of Public Health in Baltimore and Makerere University in Uganda — conducted two clinical trials involving 3,393 uncircumcised men ages 15 to 49.

According to a study published in International Journal of Sport Nutrition and Exercise Metabolism, reporting on the research from a blind experiment involving placebo controlled human trial, the daily intake of 500 mg of Grecunin extract during the course of eight weeks, greatly lowered the levels of body fat and estradiol in resistance training individuals, and at the same time it increased the total lean body mass and the levels of available testosterone.

Bronson spends her days managing the care of cancer patients involved in clinical trials, research exploring everything from new drugs that haven't yet been approved by the FDA to new uses for current drugs.

Much of the research to date has been promising, Smoliga says, but most studies — like those led by Das — involve only laboratory experiments and animal trials.

In this 8 - year trial, involving 41,186 particpants of the Black Women's Health Study, research data confirmed inverse associations between magnesium, calcium and major food sources in relation to type 2 diabetes that had already been reported in predominantly white populations.

Most randomized field trials involve measuring the effects of an intervention on individual research participants.

Of the 21 schools involved in the trial, 19 agreed to take part in the research portion, which included interviews with students, teachers, school leaders and network coordinators.

Support for research projects and clinical trials involving PET, as well as the acquisition of the scanner, was provided by the Grayson - Jockey Club Research Foundation and private donations throresearch projects and clinical trials involving PET, as well as the acquisition of the scanner, was provided by the Grayson - Jockey Club Research Foundation and private donations throResearch Foundation and private donations through CEH.

After participating in research projects as a resident, Dr. Gill remains involved in collaborative research and clinical trials.