Sentences with phrase «trial studies how»
This phase II trial studies how well chemotherapy and radiation therapy work in treating younger patients with newly diagnosed central nervous system germ cell tumors.
http://www.danafarberbostonchildrens.org/ Not exact matches
Besides randomized controlled clinical trials, there are a number of ways researchers can study how a particular cancer treatment is playing out in the real world: there are retrospective studies, observational studies, and even prospective research done using patient registries.
A recent study looked at how 244 compounds in 413 clinical trials fared for Alzheimer's disease between 2002 and 2012.
I cant praise God enough for the internet we cant be ignorant these if we want to learn anything all we have to do is to jump on the internet for answers since I have accepted Jesus as my personal savior thirty five years ago i cant stop myself to share my experience with people but since i lost my husband through a tragic accident my life took a different turn my savior became more personal and real to me i give myself full to the lord and the result of that people stat asking me for bible study which i have never done in my life so I decided to search the net and i came across your website which put the whole gospel in a simple way and i am going to use it for my first bible study and see how the holy spirit will lead from there.I came to the conclusion that our trials is a blessing in disguise and i praise God for it.keep up the good work God bless Martina keep me in prayer please
Hendrix et al: Moving on to section II, labeled Randomized Controlled Trials (RCTs), I am once again wondering how RCTs can be ethically conducted to study birthplace.
Clinical trials are studies that are conducted to see how one can «outgrow» a food allergy.
«The Joe Percoco corruption trial is now the Todd Howe show — and a case study in how Albany's lobbyists, their clients and administration officials frequently maneuver around the state's under - enforced ethics and disclosure laws.»
Corruption Trials and Two Reform Reports Make the Case for Action Now In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LSTrials and Two Reform Reports Make the Case for Action Now In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LStrials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the -LSB-...]
In light of the corruption trials of two former legislative leaders taking place this week and New York State's D - minus grade in how it handles issues of integrity from a national comparison study, New York's leading good government groups today called upon the New York State legislature and governor to complete the job of reforming our laws governing public ethics.
In the many responses to Gov. Cuomo's efforts to introduce formal and public teacher evaluation, teachers, union leaders and educational leaders have offered little but delaying tactics, such as more study is needed or how about conducting small trials.
City Councilwoman Helen Rosenthal has proposed a bill calling for a trial car - free Central Park from June through September next year, followed by a DOT study of how that affected surrounding traffic patterns.
Since the neuronal death can be recapitulated in directly reprogrammed patient neurons, Yoo said the new technique offers a way to study the details of how potential therapies — including drugs that are currently being tested in clinical trials — could rescue medium spiny neurons from death.
Unlike many clinical trials that emphasize relief of symptoms as their primary objective, the ezogabine study's goal is to gauge how well the therapy addresses some of the biological underpinnings of depression — in this case, whether the drug lessens the hyperactivity of the reward circuit that includes VTA neurons.
«This study's results can have practice changing implications on how future prostate cancer trials are designed in terms of identifying the men for these studies who are at high risk for early death due to ineffective initial treatment for their prostate cancer,» stated Anthony Victor D'Amico, MD, PhD, chief, Genitourinary Radiation Oncology, Brigham and Women's Hospital and senior author of the study.
A damning report on how the University of Minnesota (UM) protects volunteers in its clinical trials concludes that researchers inadequately reviewed research studies across the university and need more training to better protect the most vulnerable subjects.
Armed with the knowledge of how to study vaccines appropriately, scientists ideally should have no trouble conducting proper trials.
To better understand how the penile microbiome differed between men who did and did not become HIV - infected during the trial, 136 men who remained HIV - uninfected during the two - year trial (controls) were also studied.
Next, researchers would like to study how the two - drug approach works in humans, although no clinical trials have yet been designed or scheduled.
In our trial, however, the addition of radiation therapy directed at each of the cancerous areas greatly improved how patients responded to subsequent rounds of chemotherapy,» said Puneeth Iyengar, MD, PhD, lead author of the study and an assistant professor of radiation oncology at the University of Texas Southwestern Medical Center in Dallas.
The first of its kind, the study applies the method of field experiments, or randomized controlled trials, to the question of how effective PES is.
A drug with similar effects might generate substantial marketing... The very high heterogeneity... of effects among trials in the accompanying study highlights a research opportunity — to identify how to maximise the effect.»
During a conversation this month in his office at Weill Cornell Medicine in New York City, Fine rattled off more dismal stats, like the many failed clinical trials of experimental drugs for glioblastoma; like the paltry increase in life expectancy for people with glioblastoma from 12 months in 1990 to 15 today; like the stupid (in hindsight) assumptions about how glioblastomas grow and how to study them in mice.
Two drugs recently showed promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue.
To understand how this pathway is implemented, in a recent study published in JAMA, researchers at Brigham and Women's Hospital and the London School of Economics and Political Science (LSE) examined the pre-approval and post-approval clinical trials of drugs granted FDA Accelerated Approval between 2009 and 2013.
Commenting on the trial, Dr Alice Shaw, director of thoracic oncology at the Massachusetts General Hospital Cancer Centre in Boston, US, said: «This is the first randomised study to examine how a second generation ALK inhibitor compares to standard second line chemotherapy in ALK positive patients who failed the standard first line therapy, which currently is crizotinib.»
The authors point to studies of harmful and beneficial effects of thrombolytic and antiarrhythmic drugs for myocardial infarction, for example: «Not only would systematic reviews... have reduced waste resulting from unjustified research, they would also have shown how to reduce morbidity and sometimes mortality, both in patients allocated to relatively less effective or actually harmful treatments in unnecessary trials, and in patients generally,» the authors write.
► «A damning report on how the University of Minnesota (UM) protects volunteers in its clinical trials concludes that researchers inadequately reviewed research studies across the university and need more training to better protect the most vulnerable subjects,» Jennifer Couzin - Frankel wrote Monday at ScienceInsider.
«Our findings are in line with previously published studies focusing on adult trials, which may speak to how commonplace discontinuation and non-publication are in medical research in general,» says coauthor Natalie Pica, MD, PhD, a resident at Boston Children's.
The clinical trial will attempt to prove that the surgery is safe in young children and allow researchers to study how the brain develops over time and how it learns to hear sound and develop speech.
Pharmacogenomics — the study of how genes affect responses to drugs — is becoming more important in drug - development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.
«There are a lot of questions about how to implement it,» says Connie Celum, an HIV researcher at the University of Washington in Seattle, who led a large trial of the drug in East Africa and has begun studies to answer practical delivery questions, such as which subsets of people are at highest risk.
Budimirovic says the current study updated the 2013 recommendations by using a more systematic approach that classified existing outcome measures as either being able to detect shorter - term changes (measures in FXS placebo - controlled trials lasting less than 12 months) or longer - term changes (lasting longer than 12 months) changes and by grading the measures» quantitative properties using the COnsensus - based Standards for the selection of health Measurement Instruments (COSMIN) system, an initiative that aims to improve how health measurement tools are selected.
We would like to consider doing it on a larger scale, maybe having several universities studying patients with different diagnostic categories to see how a controlled psychotherapy trial produces physical brain changes as a result of treatment.
«But further study is needed, hopefully with a larger trial where we can more closely look at how the diet might help fatigue and possibly affect other symptoms of MS.»
The series started in 2009, when the U.S. government funded a team of researchers to recruit and study participants for the Testosterone Trial — a group of seven long - term studies of how testosterone therapy affects sexual activity, energy level, memory, heart and bone health, and the ability to walk a certain distance.
Authors of published trials often fail to preregister details of what they plan to study and how they'll measure it, enabling data manipulation, selective reporting of results and self - serving interpretations of findings.
The results are encouraging and we now need larger trials to understand whether the effects we saw in this study translate into long - term benefits, and to study how psilocybin compares to other current treatments.»
And the cohort could test mobile devices to study how exposures and physical activity affect health and provide volunteers to participate in clinical trials, the report says.
We need studies like this to find out how the two are intertwined and hopefully find the right formula to help prevent Alzheimer's disease,» said Dr. Rong Zhang of UT Southwestern, who oversees the clinical trial and is Director of the Cerebrovascular Laboratory in the Institute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas, where the Dallas arm of the study is being carried out.
It's not exactly clear how they did it, but the survivors of the grueling 553 - day trial are now back here on Earth for study.
An accompanying editorial said the trial showed «how a well - coordinated and highly collaborative multinational team of investigators can efficiently conduct a potentially practice - changing study.»
Led by Waisman Center and College of Agricultural and Life Sciences investigator Denise Ney and her graduate student Bridget Stroup, the study represents the first human clinical trial to compare how different PKU - specific diets affect the bone health of people living with the disease.
These additional studies are intended to help researchers better understand issues such as why some patients in the trial did or didn't respond to a new treatment or how treatments affect patients» quality of life.
Deep learning tools could help us find answers to these questions, which have huge implications on everything from how we study the disease to the way we conduct clinical trials.»
Volunteers in the safety trial will be contacted by the study sites, with information about how and when they can enroll for the OLE.
Objective: The primary objective of the present study was to estimate how large a sample size would be needed for future clinical trials for AD - modifying treatments in Japan using atrophy measures of the brain as a surrogate biomarker.
A major new paper from Sarah Tabrizi and colleagues, reporting the final outcomes of the TRACK - HD study, provides information that will help us better design trials of new therapies in HD as well as understand how the disease progresses.
In one study, the researchers conducted a review of randomized controlled trials looking at how extra calcium intake in women and men over age 50 affected bone mineral density.
The company maintains that the shift simply reflected better understanding of how Alzheimer's affects the brain; cognitive declines happen before functional ones, so detecting the latter would take a longer, more expensive study than an 18 - month trial.
Even though it is still hard to explain exactly how acupuncture works from a western medical paradigm (I'm talking controlled studies and randomized trials here), it is hard to deny the results that many patients experience everyday.