Sentences with phrase «trigger chemical signals»

About 30 percent of medications on the market activate G - protein coupled receptors on cell surfaces and trigger chemical signals inside cells to yield their therapeutic effects.

Not exact matches

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

The new microbiota may trigger weight loss, says gastroenterologist Lee Kaplan of Massachusetts General Hospital, by sending chemical signals that cause the human host to burn more calories, which helps use up the body's fat reserves.

To discover this, Hui Liu, Gene Robinson, and Eric Jakobsson of the University of Illinois developed new computational tools to analyze patterns of gene conservation across a wide range of animals, for genes activated and inhibited in the honey bee brain by exposure to a chemical communication signal that triggers alarm.

However, in people with asthma, the M2 cells and the chemical signals they emit linger and call in other cells that cause inflammation that can trigger an asthma attack with the classic symptoms of difficulty breathing, wheezing and shortness of breath.

The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.

The signal - sending neuron pumps chemicals into the space, and the signal - receiving neuron takes up some of them, triggering a new electric pulse.

Similarly, the signals trigger an increase in toxic chemicals such as nitric oxide, quinolonic acid, and kynurenic acid, which are bad for the functioning of nerve cells.

When attractant or repellant chemicals attach themselves to receptor sites on the surface membrane of a bacterium, it triggers a process within the cell that leads to the modification of the signal protein, CheY (pronounced «Key - Y»), enabling it to bind to the switch and change the bacteria's direction of movement.

Several long - lived worms carry mutations in a gene involved in a process that appears to use chemical signals to trigger activities inside cells.

Further testing in the laboratory dish showed that hematopoietic stem cells from the sleep - deprived mice responded less strongly than their peers to naturally occurring chemical signals that trigger cellular migration.

This transformation is triggered by chemical signals, which could be blocked in order to stop cancer cells from spreading.

Genetic analysis of the activated cells in the two groups of mice showed that the neurons triggered by a full belly released glutamate, a chemical that nerve cells use to signal one another, while the neurons triggered by hunger released a different neurotransmitter, known as GABA.

The study, to be published early online Feb. 9, points to two chemical signals — interleukin 15 and retinoic acid, a derivative of vitamin A — as triggers for the inflammatory response to gluten, a protein found in many grains that causes celiac disease.

Certain chemical pollutants can trigger such changes by mimicking or altering the action of the body's hormones, important signaling agents.

Because sorafenib inhibits the chemical signals that can trigger both cellular proliferation and new blood vessel growth, Gomberg - Maitland and colleagues suspected it might slow the growth and thickening of the pulmonary artery walls.

When the body is attacked by microbes, macrophages release a flurry of chemical signals that trigger inflammation.

One role of these chemical signals is to trigger the production of the mucosal secretions that protect the stomach and esophagus from acid.

Pheromones are species - specific naturally occurring chemical signals that are excreted or secreted by an individual to trigger a social response in that same species.

At spawning time, chemical signals trigger clams to release either sperm or eggs, the largest releasing up to 500 million eggs at one time.