«Among the several potential intestinal luminal stimuli that can
trigger zonulin release, we identified small intestinal exposure to bacteria and gluten as the two more powerful triggers.
Not exact matches
Zonulin is
triggered by gliadin which is the protein found in the grains wheat, rye, and barley.
However, two main
triggers have been identified to produce
zonulin and are thought to contribute to increases in intestinal hyperpermeability in everyone who has a gut wall, not just people with autoimmune disease.
High levels of
zonulin can be which can be
triggered by gluten, parasites, candida, and harmful bacteria.
Though
zonulin is cleared rapidly from circulation, the presence of
zonulin in the blood
triggers an immune response and the production of
zonulin - specific antibodies.
In the small intestine, gluten
triggers the release of
zonulin, a protein that regulates the tight junctions between epithelial cells and therefore intestinal, but also blood - brain barrier function.
The presence of gliadin in the intestine has been shown to
trigger the release of
zonulin.
(SIDE NOTE: gluten
triggers inflammatory
zonulin signaling in the body REGARDLESS of any sensitivity to gluten / gliadin proteins).
Research shows that
Zonulin expression can be
triggered by many things, like certain bacteria and foods like gluten.
It is Dr. Fasano's team discovery that «
zonulin,» is the molecule which regulates intestinal permeability (also known as «leaky gut») and their totally ground - breaking research that linked an overproduction of
zonulin (gluten is a clear known
trigger for such in celiacs) to the development of a series of autoimmune diseases, including Type 1 diabetes, celiac disease and multiple sclerosis (at least in animals at this point in time).
They are also high in gluten, which
triggers the intestines to release the protein
zonulin.