Sentences with phrase «triggers changes in the cell»

In both cases, Reiser says, «The question was, what triggers the changes in the cells?»

Not exact matches

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

Within the cell, they can trigger changes in gene expression and biochemical reactions, among other things.

«This follicular hypoxia triggers a cascade of biochemical changes in the cumulus cells.

The bacteria Helicobacter, believed to be a cause of stomach cancer, has been shown to trigger potentially cancer - inducing epigenetic changes in gut cells.

Now we know that changes in RNA of the cumulus cells triggered by aging - induced hypoxia, are the key messengers.

Korn and Waisman have discovered that IL - 6 does not trigger the decisive change in the T cells in either of those cases.

Stories on a possible cause for severe morning sickness and how a mother mouse's care for her pups might trigger changes to the genomes in their brain cells

The binding triggers the β2AR to change shape and release a «G» protein, which in cells binds to the inside end of the receptor.

Metabolic changes, caused by a poor diet and a sedentary lifestyle, trigger's the genetic reprogramming of cells in the body and joints.

«Elevated calcium triggers multiple signaling pathways that promote cell doubling, survival and changes in the cell that promote cancer invasion and metastasis,» says Dr. Copland.

So researchers began testing genes that were only active in embryonic stem cells to try to pin down those capable of triggering the change.

The results suggest the simultaneous activation of certain molecular pathways — actions among molecules in a cell that can lead to change — in particular the MAPK and PI3K cellular pathways, triggered tumor initiation and produced increasingly dense low - grade gliomas that quickly progressed to glioblastoma multiforme (GBM).

Research suggests that very scarce chemical cues can trigger physical changes in the cell, including remodeling the plasma membrane and recruiting cytoskeletal machinery, to transform the dichty from a fat, happy cell to an elongated cell with a distinct front and rear end, ready to migrate.

Known as gustducin, the protein triggers a cascade of chemical reactions that lead to changes in ion concentrations within the cell.

Activating RXR triggered a cascade of changes in muscle precursor cells and white fat that ultimately converted them into brown fat - like cells.

A lack of oestrogen or the corresponding cell receptors where it can bind results in the overproduction of RANKL, which triggers a variety of pathological bone changes.

To find out, he engineered cells in culture to contain either the heat - or cold - sensitive TRP receptors, which when triggered change the biochemistry of the cell in a measurable way.

When these cells are illuminated by a strong light, a change in the structure of melanopsin triggers a molecular cascade that eventually leads to an influx of calcium ions into those neurons and an electrical pulse.

This communication triggers a change in the scaffolding of the cell perimeter — altering from a fixed shape, attached to an organ, to a less stable one, moving freely around the body.

These interactions trigger a conformational change in gp41, causing a pH - dependent fusion of the viral and the host cell membranes and thus the delivery of the viral payload.

She wants to expose how immune cells sense pathogen - triggered changes in fatty acid synthesis and then relay the message to limit inflammation.

Howard Hughes Medical Institute researchers have discovered that a gene commonly mutated in a wide range of cancers can single - handedly trigger pre-cancerous changes in cells.

A team of scientists from Whitehead Institute and the University of Texas Southwestern Medical Center has added markedly to the job description of prions as agents of change, identifying a prion capable of triggering a transition in yeast from its conventional single - celled form to a cooperative, multicellular structure.

The scientists found that exposure to paracetamol or ibuprofen triggers mechanisms in the cell that make changes in the structure of DNA, called epigenetic marks.

Molecules in the extracellular environment bind specifically to cell - surface receptors and trigger intracellular signaling, eventually leading to changes in cellular physiology.

Fortunately, experiments done by Dr. Jan Vijg at the Albert Einstein College of Medicine and others on mutations (changes in base sequence in DNA) and additional studies commissioned by SENS Research Foundation on epimutations (changes in the arrangement of methyl groups) suggest that these latter kinds of alterations - the kind that accumulate in cells without triggering apoptosis or senescence or contributing to cancer - accumulate too slowly to make a difference with the current lifespan.

Researchers have answered an important question in biology by discovering the exquisite mechanism by which channels in the cell membrane sense voltage changes that trigger them to snap open or slam...

Finally, there is evidence that the DNA in our cells is protected by naturally occurring substances in Brussels sprouts, and since many environmental toxins can trigger unwanted change in our DNA, Brussels sprouts can help prevent these toxin - triggered DNA changes.