The phrase
"tuberculosis bacterium" refers to a type of bacteria that causes tuberculosis, which is a serious and contagious lung disease.
Full definition
A new molecule that reveals active
tuberculosis bacteria in coughed - up mucus and saliva could simplify TB diagnoses and speed up tests for detecting strains of the disease that are resistant to drugs.
Malama has detected a large degree of genetic variation amongst M. tuberculosis in humans in this area of Zambia and has also found that
M. tuberculosis bacteria isolated from humans and cattle respectively are related.
A Johnson & Johnson research team identified a new compound known as R207910 that kills the M.
tuberculosis bacterium by inhibiting the cell's energy - producing machinery.
A 2014 study
found tuberculosis bacteria DNA in 1,000 - year - old Peruvian bones; in a surprise twist, it was not the European strain, but one likely contracted from seals.
Using the second drug with bedaquiline
made tuberculosis bacteria more vulnerable, pointing to a potential strategy for dealing with persistent infections.
MARKING MICROBES
When tuberculosis bacteria, seen in this scanning electron micrograph, gobble up a new synthetic molecule, they glow under a microscope — making them easy to spot in tests.
Some strains of multidrug resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug -
susceptible tuberculosis bacteria, according to a study published this week in PLOS Medicine.
Finds of similar genotypes of M. tuberculosis in humans and cattle and of M. bovis in humans, cattle and Kafue lechwe in Namwala indicate that the
same tuberculosis bacteria are circulating between humans and animals.
Sidney Malama's doctoral research shows that Mycobacterium tuberculosis, which is the most
prevalent tuberculosis bacterium in humans, also occurs in cattle in Namwala.
Through a partnership with graduate student Amy Wright of the Florida Atlantic University's Harbor Branch Oceanographic Institute, the team screened 4,400 chemical extracts derived from extracts of sponges and other marine organisms to see if they could kill the
dormant tuberculosis bacteria.
The team identified 26 compounds that were active against
replicating tuberculosis bacteria, 19 killed dormant bacteria including seven that were active against both.
Researchers from UT Southwestern Medical Center have identified a new way that
tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore.
Furthermore, we demonstrate the potential for improving diagnostic efficiency by using simple image processing software to label and
count tuberculosis bacteria in a captured image, relieving healthcare workers of the time - consuming and error - prone task of counting by eye.
«Our study results describe precise mechanisms that
enable tuberculosis bacteria to persist in the body, which is central to the infection's deadliness,» says senior study author Kathryn Moore, PhD, the Jean and David Blechman Professor of Cardiology at NYU Langone.
The newly published study describes
how tuberculosis bacteria cause mammalian immune cells, called macrophages, to make more of a key snippet of genetic material.
«For example, in people with latent TB infections,
Mycobacterium tuberculosis bacteria are walled in by clumps of immune and other body cells in what is thought to be an extremely low oxygen environment.
Despite having been vaccinated against the disease in 1989, which was 3 years before Sousa and her colleagues examined them, 58 % of the Indians had a weakened or nonexistent immune reaction in skin tests that measure cell response to
the tuberculosis bacterium.
In tomorrow's issue of the Proceedings of the National Academy of Sciences, researchers report that more than half of the Yanomami people who had been vaccinated against TB do not produce a regular immune response to
the tuberculosis bacterium.
Bruce Rothschild, a rheumatologist at Northeastern Ohio Universities College of Medicine, and Larry Martin, a paleontologist at the University of Kansas, have turned up fossil evidence that forerunners of cows brought
the tuberculosis bacterium to North America long before European colonists introduced the disease.
An outbreak in South Africa of an extremely drug - resistant strain of
the tuberculosis bacterium is raising international alarm.
n many developing countries, a significant fraction of the tuberculosis burden comes potentially from
the tuberculosis bacteria carried by animals, essentially cattle.
Tuberculosis bacteria have thick cell walls that drugs have difficulty penetrating.
But if
the tuberculosis bacterium is resistant to antibiotics, recovery can take up to two years.
It can be both dangerous and difficult to study
the tuberculosis bacterium, but CEMIR's new high - risk laboratory now makes such research possible.
The new drug cleared the mice of
all tuberculosis bacteria after only 10 weeks of treatment.
The tuberculosis bacterium has been called the world's most effective pathogen.
VIC - 008 is a fusion protein combining an immune - activating protein from
the tuberculosis bacteria with a small antibody fragment targeting mesothelin, a protein expressed in several types of tumor — including mesothelioma, pancreatic and ovarian cancer.
French fur traders brought strains of
the tuberculosis bacteria (inset) to Canada, where it spread to native populations.
Beaver hats may no longer be chic, but
the tuberculosis bacterium has held on to one remnant from the 18th century Canadian fur trade: a genetic signature of how the disease spread from European immigrants to indigenous peoples.
The tuberculosis bacterium tends to stick around in the body, causing additional illness down the line.
It is caused by the Mycobacterium
tuberculosis bacterium, which attacks the lungs and other organs.
«We think that cutting off vessel growth to
the tuberculosis bacteria effectively strangles the pathogen and makes it an easier target for the immune system,» Stefan Oehlers said.
The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from
the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.
At right, following drug - dose combination treatment,
tuberculosis bacteria have been killed.
Plantain may also slow the growth of staphylococcus infection and
tuberculosis bacteria.