he body responds to
tuberculosis infection by locking the bacterial offenders into tiny clusters of immune cells called granulomas, which are a hallmark of the disease.
Not exact matches
The study followed 1,055 household contacts of 213 individuals with MDRTB
infection (defined
by resistance to the drugs rifampicin and isoniazid), and 2,362 household contacts of 487 individuals with drug - susceptible
tuberculosis for up to three years.
William Castell, chair of the Wellcome Trust, praised Farrar in a statement as «one of the foremost scientists of his generation, whose work — much of it funded
by the Trust — has contributed to better understanding, surveillance, prevention and treatment of diseases including emerging
infections, influenza,
tuberculosis, typhoid and dengue.»
A recent discovery
by Cornell University researchers could lead to a new, effective treatment for persistent
tuberculosis infections.
An earlier form of the vaccine was used in the DarDar Trial, a seven - year study in Tanzania sponsored
by the U.S. National Institutes of Health involving patients with HIV
infection who at birth had received BCG, the current
tuberculosis vaccine.
TB is caused
by infection with the bacterium M.
tuberculosis.
Tuberculosis, leprosy, and Legionnaire's disease are
infections caused
by different species of bacteria.
Those infected have about a 10 % lifetime risk of becoming ill with active
tuberculosis; however, this risk is much higher for people whose immune system is compromised
by HIV
infection, malnutrition or other illness.
Pharmacological Inhibition of Host Heme Oxygenase - 1 Suppresses Mycobacterium
tuberculosis Infection In Vivo
by a Mechanism Dependent on T Lymphocytes.
Anna Huttenlocher, University of Wisconsin, USA Neutrophils in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality in pulmonary
tuberculosis Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial
Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and Plasticity Do glia drive synaptic and cognitive impairment in disease?
Caused
by a bacterial
infection with Mycobacterium
tuberculosis (MTb), TB most commonly affects the lungs but can affect any organ in the body.
The primary causative agent in humans is Mycobacterium
tuberculosis, whereas TB in wildlife results from
infection by Mycobacterium bovis.
By then,
tuberculosis has become a persistent
infection that can only be contained.
· Changing nature of disease means that
infections with drug - resistant
tuberculosis will be increasingly caused
by person - to - person
infection, rather than non-resistant strains acquiring resistance.
Biologics work
by suppressing the immune system, which can make patients more susceptible to
infections, ranging from the flu to
tuberculosis.