Sentences with phrase «tuft cells in»

Identifying a role for tuft cells in the interactions between the virus and its host «is a significant step forward,» says immunologist David Artis of Weill Cornell Medicine in New York City, who was not involved in the study.

If norovirus also targets tuft cells in humans, «maybe that's the cell type we need to be treating,» says study coauthor Craig Wilen, a physician scientist at the Washington University School of Medicine in St. Louis.

Interglomerular Lateral Inhibition Targeted on External Tufted Cells in the Olfactory Bulb.

Not exact matches

In mice, norovirus infects rare cells in the lining of the gut called tuft cellIn mice, norovirus infects rare cells in the lining of the gut called tuft cellin the lining of the gut called tuft cells.

Now, researchers at Washington University School of Medicine in St. Louis have shown, in mice, that the virus infects a rare type of intestinal cell called a tuft cell, so named because each cell sports a cluster of hairlike extensions on its surface.

«This raises important questions about whether human norovirus infects tuft cells and whether people who have chronic norovirus infections and continue to shed the virus long after infection do so because the virus remains hidden in tuft cells,» Wilen said.

The new study indicates that such infections in the mice cause the number of tuft cells to increase by five - to tenfold, leading the norovirus to replicate more efficiently.

And tuft cells are known to increase in number during these parasite infections.

These «wires» are projected from cells involved in receiving incoming odor signals from neurons in the nose, and local cells in the bulb that modulate them — including short axon (SA) cells (brightly illuminated in this view) and external tufted (ET) cells.

After eight weeks, hair cells in treated ears resembled those in healthy animals — densely packed and tufted with hairlike bundles.

The answer to this question has been slow in coming, as the tufted cells are extremely small — much too small for sticking an electrode into them and capturing their electrical signals.

«We were surprised to see that expression of the gene TSLP — which encodes a cytokine long known to be involved in epithelial - induced inflammation — was exclusive to a particular subset of tuft cells,» Haber noted.

And since the gut microbiome plays a role in regulating tuft cells, this a rare case of antibiotics being able to impact a viral disease.

The authors speculate that treatment of the mice with broad - spectrum antibiotics would kill multiple pathogens in the gut and alter the biome so that the proliferation of the tuft cells would be prevented.

Ordinarily, Coffin specializes in fish hearing — studying the hair - like tufts of sensory cells arrayed along each side of zebrafish in what is called the lateral line.

Key to each of these units is a structure known the «glomerulus», in which podocyte cells wrap themselves tightly around a tuft of capillaries separated only by a thin membrane composed of extracellular matrix, and leave slits between them to build an actual filtration barrier.