Sentences with phrase «tumor after therapy»

In some cases, a minority of cells called TICs, or cancer stem cells, are culpable of repopulating the tumor after therapy.

These cancer stem cells act like the seeds of cancer and are responsible for re-growing a tumor after therapy.

Not exact matches

The FDA approved a Lutetium - 177 based cancer therapy called Lutathera for the treatment of neuroendocrine tumors earlier this year, after Novartis snapped up the developer, Advanced Accelerator, at a premium.

Some weeks later, after radiation therapy that was designed to limit the extent of the surgery, he wrote to tell me that the doctors were astounded to learn that the tumor had been stopped cold by the radiation and that surgery would not be required.

This study analyzed preserved tumor samples from 43 prostate cancer patients who later received radiation therapy after rising PSA levels were detected following a radical prostatectomy.

In particular, the study suggests that two miRNAs — miR - 4516 and miR - 601 — in tumor cells along with Gleason score and lymph node status may help identify patients who might experience rising PSA after they've been treated with radiation therapy.

To uncover how this resistance occurs, Guo and Lu teamed with Xu, Herlyn and colleagues examined both cell lines and tumor biopsies from melanoma patients before and after either BRAF inhibitor therapy or BRAF / MEK inhibitor combination therapy.

With these in vitro test methods, the KU researchers have shown that anti-CD44s antibody can reduce pancreatic cancer cell growth, metastasis and ability of the tumors to recur after radiation therapy.

Now that we know more about how cancer originates and how tumors re-grow after treatment, we can design new therapies to prevent this.

«In order to block tumor recurrence after radiation therapy, we used an antibody to target and inhibit these cancer stem cells,» said Dr. Xu.

Glioblastoma accounts for about 15 percent of all brain tumors, is resistant to current therapies and has a survival as short as 15 months after diagnosis.

While the patient eventually relapsed and died more than a year after CAR T - cell therapy, the brain tumor never recurred.

In addition, when a subcutaneous tumor began to recur two months after CAR T - cell therapy and a surgical biopsy was performed, the CAR T - cells spontaneously re-expanded and the tumor again went into remission, and phenomenon that had not previously been reported.

The study, which followed four individuals for a year after they were treated with embryonic stem cell - derived retinal pigment epithelial cells for macular degeneration, observed no serious side effects (tumor growth or other unexpected effects) related to the therapy.

He says that if future trials are successful, the experimental vaccine, which can be made relatively quickly and cheaply, could become a short - term therapy administered immediately after diagnosis to try to keep tumors in check.

«We identified patients who had both contrast - enhanced digital mammography and MRI after treatment to shrink their tumors and before additional therapy or a mastectomy.»

Oncologists have long known that in rare cases, after patients receive radiation therapy to shrink a tumor, the immune system will mount an aggressive response that wipes out not only the tumor, but metastases throughout the body that hadn't been treated with the radiation.

If it proves as effective in people as it is in mice, a vaccine could one day be given to cancer patients after surgery, radiation therapy, or chemotherapy to prevent tumors from regrowing.

Their latest pledge came after Druker recently lobbied the couple for another $ 1 billion to take insights from Gleevec, as well as other so - called molecularly targeted therapies, and develop better early detection tools for tumors.

tumors from neural stem cells also contained more glioblastoma stem cells, cells that are believed to give rise to tumor recurrence after therapy,» says Lene Uhrbom, senior lecturer at the Department of Immunology, Genetics and Pathology and lead author of the study.

After four cycles of therapy (42 days), all mice receiving the combined regimen were alive, whereas mice in the other groups had to be euthanized due to tumor growth.

Type I tumors are often treated with radiation therapy, which helps stop or slow cancer growth, given in addition to or after the primary treatment.

After enrolling in a clinical trial for genetically based drug therapy, Victor's tumor has shrunk and shows no signs of growth.

Although there is currently no technology that allows early diagnosis of the disease, a number of putative markers have been identified: their detection after diagnosis would be a useful tool to monitor the evolution of the tumor during treatment, providing valuable prognostic information on response to a given therapy.

In the next year, members of the Dream Team will continue to study the tumor microenvironment before and after checkpoint blockade, to develop algorithms to identify and predict the best antigens on cancer cells that can be used for cancer immunotherapies, to analyze tumor tissues and blood for biomarkers that will help in selecting patients who will benefit, and identifying the best approaches to increase the strength of immune cells for adoptive cell therapy.

University of Texas M.D. Anderson Cancer Center Tumor - specific alloantigen - anergic donor - derived T - cell therapy after hematopoietic stem - cell transplantation

Discovery of actionable therapy targets in drug - resistant breast tumors after neoadjuvant therapy

Advanced Cancers Destined to Return After Single Drug Therapies Targeted cancer cell therapies using man - made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, the treatment stops working, and the diseaseTherapies Targeted cancer cell therapies using man - made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, the treatment stops working, and the diseasetherapies using man - made proteins dramatically shrink many tumors in the first few months of treatment, but new research from Johns Hopkins scientists finds why the cells all too often become resistant, the treatment stops working, and the disease returns.

Radiation Therapy Prolongs Life in Men with Recurrent Prostate Cancer Men whose tumors recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two years of the recurrence.

Positron emission tomography (PET) imaging of metabolic tumor burden at diagnosis and after induction therapy can help identify patients most at risk of follicular lymphoma (FL) recurrence, but more work is needed to differentiate high - risk and moderate - risk patients, suggested findings from a pooled analysis of data from three prospective clinical trials, published in Blood.

Researchers at The McDonnell Genome Institute at the School of Medicine have co-led a study on breast tumors — before and after hormone reduction therapy.

Slow down lymphoma growth modestly and show no effect on tumor regression; delay tumor recurrence with activation of p53; enhance tumor regression and inhibit tumor recurrence after alkylating drug therapy.

«The risk of breast cancer does decline after stopping hormone therapy,» she stresses, «but if a tumor has formed while a woman is on hormones its very likely to come to light even after she stops hormones, so there is some residual risk.

Another study published in the Journal of Cancer Science and Therapy found that after just 30 days of infrared treatment, tumor - infected mice saw up to 86 % reductions!

Until then, chemotherapy and radiation therapy were the two main solutions offered after removal of cancerous tumors, just like in people.

For instance, after a tumor has been surgically removed, laser therapy can reduce pain and speed up the recovery time.

If the tumor is shrinking or remaining stable in size after 4 - 8 weeks, and the dog is feeling well on that therapy, then the same treatment is continued.

Surgical treatment to remove the tumors is the optimal therapy and the largest reported series of cases to date demonstrated a mean survival time after surgery of around 500 days, which is relatively long given that affected ferrets are usually middle - aged at the time of diagnosis.

For dogs with Grade I and II tumors, recovery is excellent after surgical removal and radiation therapy.

If the tumor can not be completely surgically removed, your veterinarian may recommend radiation therapy after surgery, which has been shown to be very effective in reducing the size of the tumor.

Meta - Analysis to Determine the Diagnostic Value of 2 - 18Fluoro -2-Deoxy-D-Glucose Positron Emission Tomography in Assessing Residual Tumors after Systemic Therapy for Metastatic Seminoma