Sentences with phrase «tumor angiogenesis»
"Tumor angiogenesis" refers to the process of forming new blood vessels to supply nutrients and oxygen to a tumor. It is a key aspect of tumor growth and development, as blood vessels are necessary for the tumor to grow beyond a certain size. By promoting the growth of blood vessels, tumors can ensure their own survival and facilitate the spread of cancer cells in the body. Full definition
Today, I am the director of a research department in tumor angiogenesis, which is affiliated with both the university and the French Institut National de la Santé et de la Recherche Médicale (INSERM).
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Teodoro JG, Evans SK and Green MR. Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome.
Dr. Giannoula Klement, an internationally recognized expert on tumor angiogenesis and antiangiogenic therapy, worked with Judah Folkman elucidating the role of platelets in angiogenesis and their possible role as biomarkers in the early detection of cancer and tumor recurrence.
In a recent paper published in Scientific Reports (Nature publishing group), they explain how CCN1 signals tumor angiogenesis in pancreatic cancer.
It is known that both hypoxia and consecutive hypoxia / reoxygenation can exert a variety of effects on tumor cell biology, including activation of pro-survival signal transduction pathways, aberrant genetic and epigenetic alterations, and increased tumor angiogenesis.
HIF - 1 plays important roles in critical aspects of cancer biology, including tumor angiogenesis, regulation of glucose and energy metabolism, invasion, and metastasis.
Certain Eph receptors and ephrins promote tumor angiogenesis.
For discovering tumor angiogenesis, and for pioneering work in the development of antiangiogenic therapies for cancer.
Tissue - engineered 3D tumor angiogenesis models: Potential technologies for anti cancer drug discovery.
Fourth, vitamin C can inhibit tumor angiogenesis, the process of new blood - cell formation crucial to tumor survival.
These flavonoids have proven to be effective in reducing tumor angiogenesis.
Dr. Richard Beliveau is Director of the Laboratory of Molecular Medicine at Service de Neurochirurgie, Hopital, Notre - Dame (CHUM), and an expert on tumor angiogenesis.
Many of the endothelial cell lines described here have been considered previously inaccessible for study of tumor angiogenesis, progression, and metastasis.
Because of this lack of receptors, common cancer drugs can't «find» the cells, and doctors must treat the cancer with extremely aggressive and highly toxic treatment strategies,» said Salman Hyder, the Zalk Endowed Professor in Tumor Angiogenesis and professor of biomedical sciences in the College of Veterinary Medicine and the Dalton Cardiovascular Research Center.
Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.
In his position, Dr. Beliveau oversees a number of important angiogenesis - based research projects involving the regulation of VEGF - dependent signaling pathways, contribution of bone marrow - derived cells in tumor angiogenesis, and the identification of new molecular targets and biomarkers, among others.
We showed that the EphA2 receptor is upregulated in the tumor vasculature together with the ephrin - A1 ligand, which suggested a role in tumor angiogenesis that is now well established.
Dr. Ingber has also made major contributions to mechanobiology, tissue engineering, tumor angiogenesis, systems biology, and nanobiotechnology.
What is tumor angiogenesis?