Sentences with phrase «tumor area of»

(G and H) Representative H&E staining (G) and quantification of H&E - stained tumor area of bone lesions.

(E and F) Representative H&E staining (E) and quantification (F) of stained tumor area of bone lesions.

Not exact matches

And it was in the area of the brain that controlled emotions and many people who had a tumor in this part of the brain also had obsessed urges to write.

Though the surgery to remove the tumor was successful, post-operation tests revealed the cancer had broken into blood vessels — posing a threat that it could return to her liver or other areas of the body.

However, some areas that can resemble blood vessel tumors — called hemangiomas — may need treatment because of their location.

To that goal, Smith is launching a radiation study looking at two - to - two - and - a-half weeks of treatment of external beam treating a large area surrounding the tumor bed.

Matching unique genetic information from cancer patients» tumors with treatment options — an emerging area of precision medicine efforts — often fails to identify all patients who may respond to certain therapies.

Reducing STK17A also interfered with tumor cells» ability to move around and invade other areas of the brain.

The scientists demonstrated that chemokine CCL7 is diffused through the PPAT to the area around the prostate and that it attracts tumor cells that express the CCR3 receptor towards the periprostatic adipose tissue, the gateway to the rest of the body.

The test can help find ulcers, colon polyps, tumors and other areas of inflammation or bleeding.

This location represents a particular challenge for surgeons, since the tumors are technically difficult to access and, because of the anatomically constricted space in the lesser pelvis, the view of the operating area is restricted.

These are indications that areas of diseased tissue could be dying, while other parts of a tumor could be rapidly growing or becoming more aggressive.

Claire E. Lewis and Munitta Muthana of the University of Sheffield in England and their colleagues have designed a drug delivery scheme that takes advantage of the natural attraction of macrophages to the oxygen - starved areas in tumors.

Solid tumors also have areas of low oxygen, which promote tumor growth and metastatic spread.

Since XL184 is delivered to every part of the body and not just to the tumor when administered orally, enclosing it in the PMIL could reduce toxicity by confining its action to the area of the tumor.

Examination of gene expression in patients with non-small cell lung cancer (NSCLC) showed the area adjacent to tumors is rich with cancer markers.

This led to development of newer technology, called single cell sequencing (SCS), that has had a major impact in many areas of biology, including cancer research, neurobiology, microbiology, and immunology, and has greatly improved understanding of certain tumor characteristics in cancer.

«With this new approach, we can navigate through millions of important brain fibers and tracts to access deep areas of the brain where these benign tumors or hemorrhages are located with minimal injury to normal brain,» said Britz.

Physicians would administer the photoacoustic molecules to the patient, either by injecting into a vein or directly to a tumor site, then use the modified ultrasound machine to visualize the area of interest.

However, an analysis of the samples showed a wide variation of EGFRvIII expression in patients and over time and in different areas of their tumors.

A better approach, Monje said, would be to develop drugs that specifically block the tumor - stimulating activities of neuroligin - 3, such as a drug that stops the protein from being secreted into the area around the cancer cells.

IGRT is a common practice in both photon (traditional radiation therapy) and proton therapy to treat tumors close to sensitive structures and organs or in areas of the body prone to movement or change in shape.

It's thought that the high pressure observed in tumors is a result of these abnormal blood vessels, which leak fluid and proteins into the area between tumor cells, known as the interstitial space.

To understand the current performance and potential of this assay, the researchers first tested it in advanced cancer, an area where circulating tumor DNA has been previously characterized.

Even with the naked eye, the scientists recognized that empty area of bone indicated a tumor had once sat there.

This resolution and field of view is sufficient for identifying tumor borders, and the probe can be moved over the tissue surface to get an overview of the affected area.

Even after removal of the tumor there are microscopic cells that exist far beyond that area that was removed, and that's why these tumors come back.

When compared with MRI scans using the metallic enhancing agent gadolinium, DGE - MRI gave comparable results - showing details of brain structure and areas where tumors had disrupted the blood - brain barrier (BBB), which is a hallmark of the highest grade tumors.

«Areas of glioblastoma tumors correlate with separate subtypes of glioma stem cells.»

Areas surrounding tumors and inflammations are usually slightly more acidic than areas surrounding healthy tissue, a phenomenon possibly linked to the aggressiveness of tuAreas surrounding tumors and inflammations are usually slightly more acidic than areas surrounding healthy tissue, a phenomenon possibly linked to the aggressiveness of tuareas surrounding healthy tissue, a phenomenon possibly linked to the aggressiveness of tumors.

After first verifying that stem cells injected to the brain would travel to multiple metastatic sites and not to tumor - free areas in their model, the team injected stem cells loaded with oHSV into the carotid artery of metastasis - bearing mice..

Working with Seattle, Washington — area neurosurgeons, the Allen Institute acquired healthy cells from the cortex — the outermost layer of the brain that coordinates perception, memory, thoughts, and consciousness — from patients undergoing surgery for epilepsy or brain tumors.

Even before a successfully treated tumor starts to shrink, its metabolism and thus the pH value of the surrounding area could change.

Rarely are brain tumors situated in «silent» areas of the brain, and areas often considered «silent» nevertheless can affect complex human functions, such as relationships, employment and decision - making.

Dr. Levitsky: Other sections under the Oncology Discovery and Translation Area (DTA) focus on anti-angiogenesis, small molecule inhibitors of the p53 pathway, apoptosis, signal transduction, and the tumor microenvironment.

Tumor sizes decreased in the treated mice, areas of cell death were visible, and all AAV2 treated mice survived through the study, a direct contrast to the untreated mice.

City of Hope is a leader in image - driven radiation planning, using advanced imaging technologies — such as computed tomography, magnetic resonance imaging and positron emission tomography scans — to determine tumor size and location and «sculpt» radiation delivery to the cancerous areas.

There may be areas of dead cells in the tumor.

The area around the tumor is a hostile environment that disarms immune cells and deprives them of the ability to kill tumor cells.

While much recent research has not been published in this area, there is actually a long history of studies that show: (1) there is a significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against cancer can be generated by vaccinating animals with embryonic tissues.

Each tumor site was represented by four cores from different areas of the specimen; two cores from each tumor site were included in each of two TMA blocks (8 cores of each patient in total).

For AQUA analysis, 2 pairs of slides (containing two cores from different areas of each matching primary and metastatic tumor per patient) or test arrays of cores from FFPE placental tissue and MEL624 cells not overexpressing or overexpressing PD - L1 were concomitantly stained.

There may be a slow - growing tumor in certain areas of the brain that can cause dementia symptoms.

Combining immunotherapies directed at the patient with more traditional therapies, like chemotherapy and radiation, which are directed at the tumor, is another area of intense scientific interest.

Although extensive efforts have been devoted to understanding the effect of hypoxia on tumor progression, two areas of tumor biology remain unclear.

The injectable medication cures or reduces the size of malignant skin tumors and can prevent scaring from surgery in areas difficult to operate on such -LSB-...]

2004: IMRT (Intensity Modulated Radiation Therapy) Program began to deliver high - precision radiation that conforms to the three dimensional shapes of tumors and delivers higher and well defined doses of radiation to tumors, and even specific areas within tumors, while minimizing radiation to surrounding normal tissue.

This Institute is conducting ground - breaking research in the area of tumor biology and the development of cancer biomarkers using genomic and proteomic technologies in the hands of world - class scientists.

He has over 250 publications in the areas of signaling by growth factor receptors and oncogenes in breast tumor cells, development of targeted therapies and biomarkers of drug action and resistance, and investigator - initiated clinical trials in breast cancer.

My particular areas of interest are GI and pancreatic neuroendocrine tumors and pancreatic pathology.