Sentences with phrase «tumor biology»
"Tumor biology" refers to the study of the characteristics, behavior, and development of tumors or cancer cells. It focuses on understanding how tumors grow, spread, and interact with the body. By studying tumor biology, scientists try to find new ways to detect, treat, and prevent cancers. Full definition
The researchers also anticipate that it could help scientists learn more about tumor biology.
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We learned all about tumor biology, but we knew very little about the human dimensions of cancer.
And, though they were skeptical that they would observe any difference in tumor biology in the diet - treated patients with such a short - term dietary intervention, just within those few weeks, they found significantly lower cancer proliferation rates, and significantly higher rates of cancer cell death.
Future oncologists will need to have a much deeper understanding of tumor biology on a molecular level than their predecessors.
Cancer researchers are generating mounds of molecular data on tumor biology.
«With ongoing studies of the homologous recombination pathway and its impact on cancer development, we may identify additional genes that, when mutated, allow for either improved response to specific treatments or conversely, portend more aggressive tumor biology, and this could greatly inform development of new cancer therapies,» Heeke explains.
Several research teams will examine the samples using different analytical methods in order to get an overall picture,» says Tobias Sjöblom, associate professor of tumor biology at Uppsala University and director of the study.
These new models will help researchers gain new insights into tumor biology and better predict patients» responses to cancer treatment.
«We thought it was important to visit the issue of BCT versus mastectomy by tumor biology,» Bedrosian continues.
The researchers hypothesized that they would find that patients» surgical choice would matter and impact survival with tumor biology considered.
She believes the answer to why differences exist for three cancers lies in an interaction among tumor biology, hormonal responses in the patient, and genes that could affect how drugs, such as certain chemotherapies, are metabolized.
In addition to developing the new genetically engineered mouse model for the form of cancer called glioblastoma multiforme, the researchers made a key discovery about brain tumor biology via the mice.
The conference aims at bringing together international experts from different fields of cancer research to present and discuss new therapeutic approaches regarding different tumor entities as well as new findings in the field of tumor biology seeking to incorporate innovative platforms into cancer research.
Can tissue engineering concepts advance tumor biology research?
Although extensive efforts have been devoted to understanding the effect of hypoxia on tumor progression, two areas of tumor biology remain unclear.
Some other predictors which have been developed in the lab claim to predict likelihood of tumor biology deregulation.
Furthermore, the role the host microenvironment plays in tumor biology provides an exceptional opportunity for novel therapeutic strategies.
In the last 10 years, we've invested just over $ 150,000 in seven studies focused specifically on squamous cell carcinoma, melanoma, and sarcoid tumor biology and treatment.
«In addition to having a higher prevalence of triple - negative breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the study.
The study is to be directed by Tobias Sjöblom, associate professor of tumor biology at Uppsala University, Sweden.
CSC hypothesis has resulted in incredible impact on the understanding and insight into tumor biology.
Previous investigations have suggested that cfDNA and CTCs might provide complementary information about tumor biology.
«As we continue to advance our knowledge of tumor biology, we have learned that cancer cells have a remarkable ability to adapt and become resistant to targeted therapies.
One example is in tumor biology, where different cancer cells are likely to have different methylation patterns.
The positions now open range across all scientific disciplines, but most are in the natural sciences and associated disciplines, such as biophysical chemistry, cell or tumor biology, physical sciences, bioethics, and forestry.
Outcomes of children and young adults with cancer have improved, primarily due to enhanced understanding of tumor biology and due to the clinical application of biological discoveries through multicenter clinical trials.
«When factoring in what we know about tumor biology, that paradigm may no longer hold true.»
«You can look at it in terms of tumor biology — our current strategy is to treat and then as long as the tumor responds to any degree, to watch for progression without paying much attention to depth of response.
Lastly, we may need to alter the tumor biology with specific small molecules or viruses, then add or activate T cells, then block the checkpoint.»
By shedding light on subtle distinctions in tumor biology, these findings offer clues to designing more effective anticancer treatments to precisely target tumors in individual patients.
However, an overactive stimulation of mTOR in response to nutrients and growth factors — metabolic processes that are crucial in tumor biology — leads to an increase in cell growth and proliferation.
Of note, the current study is part of a recent surge in NYU Langone findings on pancreatic cancer, including studies on how first - responder cells turn off the immune response, the role of the drug nab - paclitaxel in tumor biology, cancer cells» unique fuel sources, and how immune cell infighting drives the disease.
The cancer center also administrates four master's programs (in biostatistics, health physics, tumor biology, and a joint program in cancer genetics, epidemiology, and control), as well as the PhD or combined MD / PhD program in tumor biology.
To characterize the role of the alpha2 beta1 integrin in tumor biology we utilized genetically engineered mice (GEM) in which expression of the Î ± 2Î ² 1 integrin is completely eliminated.
Additionally, three postdoctoral training programs are offered at Lombardi: a medical genetics fellowship, clinical fellowships in hematology / oncology and palliative care, and research fellowships in tumor biology.
But these problems are minuscule compared to Komen's biggest failing — its near outright denial of tumor biology.
Despite the fact that GPCRs are the largest signal - conveying receptor family and mediate many physiological processes, their role in tumor biology is underappreciated.
It deals with, among others, tumor biology, structural biology, neurobiology, bioinformatics, and enzymatic engineering.
Her background in molecular biology, cell biology, and tumor biology, as well as publications of her research, has prepared Dr. Vines to study the regulation of CCR7 - mediated tumor responses in selected murine models.
The principal areas of research focus on understanding the genetic determinants of tumor biology, exploiting the relationship of lymphoma with the immune system to develop immunotherapy and in new drug development.
This Institute is conducting ground - breaking research in the area of tumor biology and the development of cancer biomarkers using genomic and proteomic technologies in the hands of world - class scientists.
The cancer biology predictors were developed by taking gene lists from prominent papers in the literature and using them to generate signatures of tumor biology / microenvironment deregulation.
I joined the tumor biology team in the summer of 2015 after 2 years spent at the Duke Cancer Institute (USA) and 2 years at Sanofi Pasteur (USA and Canada).
Dr. Folkman's 1971 original hypothesis that solid tumors are angiogenesis - dependent initiated studies in tumor biology that extended to disciplines as diverse as ophthalmology, cardiology, dermatology and tissue engineering.
The scientists concluded that «tumor biology can be altered by either a vegan low - fat diet or eliminating simple carbohydrates accompanied by weight loss.»