Sentences with phrase «tumor cell behavior»

For the subset of more recent patients, the researchers assessed tumor cell behavior — in particular, cancer cells» ability to cross the endothelium (inner layer) of blood vessels.

Not exact matches

CCG is also developing cell lines that are cultured to represent tumor behavior in vivo, and computational methods that will help researchers understand tumor behavior and apply the resulting data to diagnoses, treatments, and cures.

The identification of the cancer cell of origin has important clinical implications, as it enables doctors to detect malignancies earlier and predict tumor behavior more accurately.

Dr. Massagué is particularly interested in the ability of tumor cells to hug blood vessels, as he suspects this behavior may be essential for the survival of metastatic cancer cells not only in the brain but also in other parts of the body where metastatic tumor growth can occur.

The Campàs lab is studying several of these questions, including how limbs are built and how mechanical changes in tumors affect the behavior of malignant cells and the growth of the tumor.

Scientists now know that what matters most in determining the behavior of a particular cancer (and its response to specific therapy) are the molecular pathways that drive malignant cell growth instead of where the tumor begins in the body.

The activation dynamics of the transcription factor NF - κB exhibit damped oscillatory behavior when cells are stimulated by tumor necrosis factor — α (TNFα) but stable behavior when stimulated by lipopolysaccharide (LPS).

«The nanoparticle mimics the behavior of NADPH oxidase, an enzyme used by immune cells to kill tumor cells and infectious agents.

They then tested the behavior of human tumor cells with and without HOXA5 by injecting those cells into the mammary fat pad of mice.

But evolutionary principals dictate that the behaviors and actions of any organism (whether plants, animals or tumor cells) come with advantages and disadvantages.

Hypoxia, or a lack of oxygen, is one example of a phenomenon that should weaken the tumor, but instead, the malignant cells are able to compensate and drive more aggressive disease behavior.

Normally, MIR506 plays an important role in regulating cell behavior; adequate levels help the cells function normally, while decreased levels trigger cell growth and expansion occurring in tumors.

However, efforts to examine the in vitro behavior of tumor cells with endothelial cells from different anatomical regions have been prohibited because, in large part, of the limited number of organ - derived endothelial cell lines available for study.

As important mediators of cell adhesive behavior, integrins play a critical role in tumor progression and metastasis.

«Single cell genomics can be applied to understand the heterogeneity of tumors, to explain how genetically identical cells may show distinct behavior, and to explore the vast, uncharacterized microbial landscape.

Biocellion is being used to model a variety of biological system behaviors, such as biofilm formation and wrinkling, microbial growth dynamics in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes in blood vessels and skin cells.

The glands lining the inner wall of the colon are the sites for most abnormal cell behavior such as uncontrolled cell growth, which results in polyps (non-cancerous growths) and later on in adenocarcinomas or tumors.

His efforts have pioneered the use of the three - dimensional «artificial skin» cultures to study the behavior of both tumor and normal cells that sustain tumor growth, a system known as the tumor microenvironment.

Wing primordia subjected to CIN are characterised by tumor - like overgrowths, metastatic behavior and malignancy to the host upon blockade of the apoptotic machinery, and this tumorigenic response relies mainly on the production of highly aneuploid cells that delaminate from the epithelium and activate a JNK - dependent transcriptional response.

Studies show that human cancer cells express high levels of the fatty acid synthase enzyme, which is associated with aggressive tumor behavior and tumor - cell growth.

Biopsy provides a complete picture of tumor type and behavior and allows us to determine if the surgical margins are clear of cancer cells.

The behavior of mast cell tumors is unpredictable.

Fibrous histiocytoma and malignant fibrous histiocytoma (giant cell tumor of soft tissue) exhibit a broad range of morphology (appearance) and behavior.

She says, «mast cell tumors can have a wide range of behavior and prognoses in the dog.»

Authored and submitted a paper for publication, «The Behavior of Brain Tumor Cells Extracted From the Pineal Gland Under Spectrum Shifts of UV Light»