Sentences with phrase «tumor cell lines»

The authors studied a standard panel of 60 established human tumor cell lines representing nine different human cancers, as well as several specimens of human primary ovarian cancer.

Previous studies using tumor cells lines suggested that these different tumor cell types may interact with each other to produce a more aggressive type of cancer.

In studies of laboratory - grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

Specifically, they looked for the ability of those compounds to interfere with transcription in human tumor cells obtained through the National Cancer Institute's collection of 60 human tumor cell lines of nine different cancer types, including melanoma and colon cancer.

Apart from patient testimonials and a few preliminary studies in tumor cell lines and in mice, critics say, there is no evidence of the safety or efficacy of the compound, popularly known as the «cancer pill» or «fosfo.»

Previously, she developed an innovative High Content Screening HTS platform, OncoPanel, to profile therapeutic cancer agents across 240 human tumor cell lines at Ricerca Biosciences (formerly MDS Pharma Services).

Lutz and Falkowski cite one study where unique chemical compounds isolated from an actinomycete strain inhabiting deep - sea sediments about 3.3 kilometers down in the South China Sea have shown potent activities against three cancerous tumor cell lines and also showed antibacterial activities.

AHERF Neurosciences Grant (G9410 -020-Y01)- Co-PI; «Differential expression and sorting of the neuron - specific class III b - tubulin isotype in human neuronal and neuroendocrine tumor cell lines maintained in an organ culture system».

Ligand - independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression.

JAX In Vivo Pharmacology Services has experience with a range of common tumor cell lines and the capability to use customer provided cancer cell lines for in vivo therapeutic...

To explore the biological function of DDX3 on cell growth control, a colony formation assay was done in several tumor cell lines (HuH - 7, HCT116, and HeLa) and normal murine fibroblast cells (NIH 3T3) under the selection of G418.

Most xenograft models for brain tumors using tumor cell lines require at least 10,000 cells.

Yu, C. et al. «High - throughput identification of specific cancer vulnerabilities in mixtures of barcoded tumor cell lines using PRISM.»

Researchers studied the inhibitory (cancer - stopping) effects of 34 vegetable extracts on 8 different tumor cell lines.

[10 - 16] Biologically active GHRH, mRNA for GHRH, GHRH - R, and splice variants of GHRH - R have been identified in surgical specimens and tumor cell lines of a multitude of human cancers, including various types of breast cancer.

Evidence demonstrating its cytostatic activity includes the finding that it inhibits the growth of a broad spectrum of human tumor cell lines in vitro.

The controversy began after Duke researchers led by Anil Potti and his mentor, cancer geneticist Joseph Nevins, reported that patterns of gene activity, or gene expression, in tumor cell lines could be used to predict how individual patients responded to various chemotherapy drugs.

But as he studied a tumor cell line derived from mice, doubts about that career path crept in.

For this study, a tumor cell line was transplanted into a rat and imaged with each of the following: conventional MRI, the radiotracer carbon - 13 (C - 13) pyruvate and hyperpolarized MRI at a resolution of 2.5 mm, Medipix positron detector, luminescence sensor and a fluorescence microscope.

Earlier approaches to creating this growth environment, pioneered by study co-author Jason Spence, Associate Professor of Internal Medicine at the University of Michigan, had used a natural matrix derived from a tumor cell line.

Every tumor cell line the researchers tested that had the epithelial marker E-cadherin and not the mesenchymal marker Vimentin, had high amounts of miR - 200.

Peter and colleagues focused their initial studies on a standard panel, known as NCI60, of 60 human tumor cell lines that can genetically be divided into two large groups, which they called superclusters 1 and 2.

RNA - seq analysis of the tumor cell line revealed a number of silenced genes (presumably including many tumor suppressors).

In the NCI tumor cell line panel, flavopiridol had significant inhibitory activity against all of the more than 60 human tumor cell lines with no clear selectivity for tumor type.

Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous human tumor cell lines and xenograft models (including human breast, prostate, and lung carcinoma) at clinically achievable concentrations.