Sentences with phrase «tumor cell transformations»

Not exact matches

The pathologist of the Department of Pathology at the University Hospital of Bellvitge August Vidal explained that «this tumorigenic transformation depends on Dicer protein that could serve as a marker for the presence of tumor cells, or as a therapeutic target.»

Inhibition of transcription (blockade of water) on tumor suppressor genes, such as p21, leads to cell transformation (growth of the cactus - like eremophytes instead of normal plants from the drought).

Melanoma is a malignant tumor resulting from the transformation of melanocytes, the cells that undertake to synthesize melanin, which protects us from the negative effects of solar radiation.

Furthermore, only those fusion - derived IEC - 6 cell clones that had undergone the changes in cellular growth indicative of neoplastic transformation produced tumors in mice.

Moreover, following transformation with H - Ras, these cells initiated tumor xenografts in immunocompromised mice with higher efficiency than their epithelial counterparts [5].

Bone marrow - derived mesenchymal stem cells undergo JCV T - antigen mediated transformation and generate tumors with neuroectodermal characteristics.

One the one hand, CIN contributes to oncogenic transformation and drives tumor cell evolution.

For example, cellular senescence is tumor suppressive and overcoming the senescence - associated cell growth arrest is a necessary step during cell transformation.

In contrast to the transformation of HMEC - DD cells, one oncogenic event is sufficient to transform Rat1 - DD cells, indicated by both anchorage - independent growth in vitro and tumor formation in vivo (Ni et al., 2012).

This in turn suppressed malignant transformation and tumor growth while enhancing cell to cell communication.

Early spaying may therefore, reduce occurrence of malignant lesions because the procedure removes the source of the hormones that cause some mammary cells to lose growth control, which puts these dividing cells at high risk for mutation and malignant transformation by environmental carcinogens.In fact, recent reports have identified activation of a specific oncogene in a number of canine mammary tumors.