Sentences with phrase «tumor cells frequently»

However, tumor cells frequently have either too few or too many chromosomes, leading to the incorrect expression of a number of genes.

Not exact matches

To understand how these multi-colored lesions originated they examined blood from these mice and found that tumor cells in circulation frequently occurred as clusters comprised of different colored cancer cells.

Although other tumor suppressors exist, what makes Par - 4 so special is that it is not mutated as frequently as other known suppressors, and it's «selective» in its actions in that Par - 4 will only kill cancer cells and not normal cells.

P53 is a tumor suppressor gene, a protein that regulates cell growth, and it is the most frequently mutated suppressor gene in cancer.

They work particularly well if the cancer cells they attack already have defects in the corresponding DNA repair pathways, as it frequently occurs in breast cancer and other tumors.

Josef Singer and Judith Fazekas, both lead authors of the study, discovered that a receptor frequently found on human tumor cells (epidermal growth factor receptor or EGFR) is nearly 100 percent identical with the EGF receptor in dogs.

Study author, Dr Timothy Humphrey said «Mutations in SETD2 are frequently found in kidney cancer and some childhood brain tumors, so we were excited when we discovered that a new drug we were studying specifically killed cancer cells with this mutation.»

Because tumor cells in the brain frequently divide, normal brain cells would remain unaffected by the electric fields, the team reports online this week in the Proceedings of the National Academy of Sciences.

mTOR pathway is frequently activated in ALK + ALCL tumors and cell lines.

31) Soh J, Okumura N, Lockwood WW, Yamamoto H, Shigematsu H, Zhang W, Chari R, Shames D, Tang X, MacAulay C, Varella - Garcia M, Vooder T, Wistuba II, Lam S, Brekken R, Toyooka S, Minna JD, Lam WL, Gazdar AF (2009) Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

Glial cell tumors and pituitary tumors are most common in brachycephalic (dogs with short, broad heads) breeds, while meningiomas are most frequently seen in dolicocephalic (dogs with long narrow skull) breeds.

Basal cell tumors frequently ulcerate and bleed and the ulcer may become infected.

These tumors (also called mastocytomas, mast cell sarcomas) are the most frequently recognized malignant or potentially malignant neoplasms of dogs.

Boxers and bulldogs are more frequently diagnosed with mast cell tumors compared to other breeds.