Sentences with phrase «tumor cells from»

The lymphoma clinical trials investigate harnessing the immune system of the patient to help clear the tumor cells from the body.

It is these same lymph vessels that carry tumor cells from breast tumors to the lungs or to other organs in a process called metastasis.

Tumor growth in different glands is usually multifocal, (meaning the tumors develop in many sites), rather than from spread or seeding of tumor cells from a single initial site.

Vitamin K also triggers a DNA - degrading protein that cancer cells normally suppress; thereby preventing tumor cells from repairing themselves effectively.

Research done on ripening bananas confirmed that TNF prevents tumor cells from growing and spreading.

Subcutaneous tumor cell implantation and purification of tumor cells from xenograft tumors.

This microscopic photo shows tumor cells from a fine needle aspiration cytology smear of a liver mass.

At the stage of carcinoma in situ, the basement membrane (BM) segregates tumor cells from the stroma.

If he can determine how to speed up engulfment of dead tumor cells from brain tissue, it is his hope to reduce the harmful inflammation that causes death of surrounding neurons.

The way in which they did this was by isolating circulating tumor cells from a drawing of blood.

In effect, Affigen uses cancer's «Achille's Heel»: the proteins which distinguish tumor cells from normal cells, that can target tumor cells for destruction with extreme sensitivity and precision.

«This was unexpected and suggests fundamental but unrecognized differences in drug action in tumor cells from different individuals having the same disease — in this case, breast cancer.»

Berkeley researchers isolated circulating tumor cells from the blood of breast cancer patients, then used microscale physics to design a precision test for protein biomarkers, which are indicators of cancer.

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA.

This would stop the tumor cells from gaining the flexibility to revert back to stem cells and allow doctors to wipe them out once and for all.

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

In this study, the researchers also showed that they could grow tumor cells from patients into organoids that could be transplanted into mice.

Using tumor cells from DLBCL patients, the scientists discovered that the inactivation of BTK in resistant tumors triggers the over-activation of alternative signals that promote tumor cell survival and proliferation.

The researchers isolated tumor cells from patients and grew them to reproduce small tumors in the lab dish.

Instead, the vaccines use killed autologous tumor cells from the patient to activate the immune system.

The chip's key feature is a tiny flow channel on a hierarchically designed pad that is optimized to capture tumor cells from the blood flowing across it.

The first stage of the trial, which involved an analysis of circulating tumor cells from a single blood draw of several dozen patients, has demonstrated strong potential.

Checkpoint inhibitors like ipilimumab — which has been on the market since 2011 — nivolumab, and pembrolizumab stop tumor cells from stimulating the receptors.

To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the researchers had detected in distant metastases, they treated tumor cells from different sites in a single patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not used in humans because of its severe side effects.

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

The primary cause of death from breast cancer is the spread of tumor cells from the breast to other organs in the body.

The team integrated three, complementary gene sequencing approaches to look for mutations in tumor cells from SS patients: whole - genome sequencing in six subjects, sequencing of all protein - coding regions (exomes) in 66 subjects, and comparing variation in the number of copies of all genes across the genome in 80 subjects.

The substance vigorously inhibited the growth of cultured tumor cells from colon, lung, and breast cancers, the team reports in the 20 January issue of Angewandte Chemie.

PTEN prevents tumor cells from growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many different types of cancer.

When researchers screened a library of more than 200 drugs and related compounds for activity against embryonal subtype tumor cells from three patients, the most promising results involved drugs that increased oxidative stress in tumor cells.

In the next phase of the study, researchers will genetically sequence tumor cells from at least 500 patients and follow the course of their disease.

Not exact matches

Later that evening I had a biopsy, where they stuck an endoscope down my throat, through my stomach and into my intestines, put a needle into my pancreas and got a few cells from the tumor.

Immunotherapy differs from more traditional cancer treatments, such as surgery (cutting malignant cells out of the body), chemotherapy and radiation (poisoning the deadly mutants), and even the newer, more precise molecular drugs that attempt to jam the protein signals that tell tumor cells to keep dividing and conquering.

The study found an increased risk of cardiac schwannoma, a tumor type that typically originates from cells found in neurons.

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

A heckler interrupted Vice President Joe Biden during a speech on Saturday, alleging the VP's son Beau Biden was killed by a tumor caused by radiation from cell phones, which prompted boos from the audience.

To determine how the cells switch from one type to another, they took three human uterine carcinosarcoma samples and sequenced the genomes of cells in two parts of each tumor: the carcinoma and sarcoma components.

Residual tumors, spawned from the remaining cancer cells, were 3.5 times smaller in the treated mice than in untreated mice.

Renal cell carcinoma, also known by the eponym Grawitz tumor, is the most common form of kidney cancer arising from the renal tubule.

Breast cancer tumors can fuse with blood vessel cells, allowing clumps of cancer cells to break away from the main tumor and ride the bloodstream to other locations in the body, suggests preliminary research.

Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors using tailored cells from individual patients.

By comparing the results to cells from paired normal tissue, researchers get a detailed molecular picture of the tumor environment, including the types and activity levels of T cells that are critical to the immunotherapy response.

Understanding how margin length decreases from surgery to pathology — because of how the removed tissue shrinks and tumor cells invade surrounding tissues — can lead to better surgical margin planning and in turn a better prognosis, said corresponding author Milan Milovancev, a board - certified veterinary surgeon at OSU's College of Veterinary Medicine.

Some tumor cells use this receptor to hide from the immune system (SN: 4/1/17, p. 24).

Recently, DNA shed from tumor cells has been identified as a noninvasive method of screening biomarkers for the early diagnosis and prognosis of cancer.

EphA2 spreads cancer by allowing malignant cells to migrate from the primary tumor into circulation and eventually to adhere to other tissues.

Even after initial purification of the sample, liquid biopsies typically contain much more nucleic acid from healthy cells than from tumors.

«We're interrogating the tumor microenvironment,» she says, «by looking at suppressive cues as well as cells and secreted proteins that protect tumors from the immune response.»

Chan's laboratory uses genomic analyses to identify neoantigens — novel peptides found only in tumors that arise from mutations accumulated by cancerous cells.