Sentences with phrase «tumor cells use»

While glucose is the main «food» for cancer cells, a study from 2010 published in the Journal of Cancer Research shows that pancreatic tumor cells use fructose specifically to divide and proliferate.

WASHINGTON, Aug 2 (Reuters)- Pancreatic tumor cells use fructose to divide and proliferate, U.S. researchers said on Monday in a study that challenges the common wisdom that all sugars are the same.

Some tumor cells use a newfound mechanism to communicate with healthy cells next to them and prompt those neighbors into forming blood vessels.

As part of the research, Castro and her colleagues determined that brain tumor cells use the mTOR pathway to hamper the immune response of patients.

Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find.

Some tumor cells use this receptor to hide from the immune system (SN: 4/1/17, p. 24).

The results were published in the journal Lab on a Chip (Lab on a Chip 17 (19), 3291 - 3299) in an article called: «Magnetic particles assisted capture and release of rare circulating tumor cells using wavy - herringbone structured microfluidic devices.»

Not exact matches

CAR - T cell therapy is a form of immunotherapy, a rapidly developing cancer treatment that uses patients» own immune cells to attack tumors.

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

Currently marketed for research use by Biofluidica, the test's microfluidic channels use specific cancer antibodies to detect capture circulating tumor cells.

Hingtgen's group is already testing how far their tumor - homing cells can migrate using larger animal models.

An immune response, triggered by foreign neural stem cells, could actually help attack tumors, says Evan Snyder, a stem cell biologist at Sanford Burnham Prebys Medical Discovery Institute in San Diego, California, and one of the early pioneers of the idea of using stem cells to attack tumors.

The 2016 People's Choice Award went to Emmanuelle Alaluf of the Free University of Brussels, for her video using ballet and other dance styles to show how tumor cells evade the immune system.

Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors using tailored cells from individual patients.

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

Tumors (red) can use PD - 1 proteins (yellow, orange) to lock onto T cells (white) and shut them down.

Chan's laboratory uses genomic analyses to identify neoantigens — novel peptides found only in tumors that arise from mutations accumulated by cancerous cells.

«Used in cancer therapy, this process could increase the impact of a treatment by heating the cancer cells while introducing the drug compound into the tumor.»

Immune checkpoint blockade therapies use antibodies to counter the defensive tactics of tumor cells.

A route used by tumor cells to spread could be exploited to make stem cells for regenerative medicine and cancer therapies

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Inspired by his own bout of leukemia to try to find a better cancer treatment, retired broadcasting station owner Kanzius guessed that as an alternative to chemotherapy, he could inject tumors with metal ions, then use radio waves to heat the metal and destroy cancerous cells.

Lo's team set out to find ways to further weaken the tumors, since the drug addiction response (which can range from a mere slow down of the cancer's growth rate to cancer cell death), can be used to improve clinical outcomes.

Also limiting the use of therapeutic stem cells to date, self - renewal, a quality so vital to a fast - growing fetus, can also be a source of cancer risk when haphazard, unlimited cell multiplication results in the abnormal tissue growth seen in tumors.

Researchers used tissue and blood samples to show that the gammopathy (a precursor to myeloma) in both mice and patients with Gaucher disease is triggered by specific lipids, and that the antibodies made by tumor cells in nearly a third of myeloma patients are directed against such lipids.

«Herpes - loaded stem cells used to kill brain tumors.»

Further preclinical work will be needed to use the herpes - loaded stem cells for breast, lung and skin cancer tumors that metastasize to the brain.

Schwarz and her colleagues used three different drugs, alone and in combination, to deprive cervical tumors of glucose and block downstream metabolic pathways that help protect cancer cells from building up toxic free radicals.

Using human - derived glioblastoma cells in a mouse models, researchers found that the modified high - fat, low - carbohydrate diet increased life expectancy by 50 percent while also reducing tumor progression by a similar amount.

«Mechanisms cancer cells use to establish metastatic brain tumors revealed by research.»

Several studies have used cell - surface markers — proteins found on the outer membranes of tumor cells — to identify glioblastoma stem cells; but the specific markers used have been controversial and can not reflect molecular processes going on within tumor cells.

Restoring normal function to a mutated protein is more difficult than simply blocking a protein, the strategy used by most medical therapies, says Klas Wiman, a tumor cell biologist at the Karolinska Institute in Stockholm.

Again, using mouse models of glioblastoma — this time created from brain tumor cells that were resistant to the herpes virus — the therapy led to increased animal survival.

The scientists conducted the research using see - through zebra fish so that they could see how the cancer cells moved and expanded from the original tumor.

Using immunostaining, the researchers counted the remaining tumor cells; the mice treated with GD2 CAR - T cells had a few dozen remaining cancer cells per animal, while each control mouse had tens of thousands of cancer cells.

The virus, redesigned using sophisticated protein engineering techniques, works: With its shield and its adapter, these viral gene shuttles efficiently infected tumor cells in laboratory animals.

«What we may be looking at,» he adds, «is a future way to prevent metastasis to many organs simultaneously» using drugs that make tumor cells let go of the blood vessels they cling to.

The researchers also used their ultrasound technique in mice to image Salmonella bacteria, which could be used to deliver cancer - killing drugs to tumor cells.

To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA sequencing to study directly, on a single - cell level, gene expression in samples from six early - stage human tumors.

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

Biology professor David Soll and his team used unique computer - assisted 3 - D reconstruction software to chronicle how both breast tissue cancer cells and melanoma cells form tumors.

Weeraratna's team used an artificial skin reconstruct model to recreate the interactions of melanoma cells with either a young or aged tumor microenvironment.

«We used the algorithms to identify typical molecular signatures of stem cells [stemness signatures] that could help us understand tumors and serve as predictors of aggressiveness or clinical outcome.»

Researchers are already using single - cell analysis to identify genetic variations within tumors and tissues, and Langsdorff says the technique is quickly establishing a foothold in microbiology as well.

The scientists went through the same process using tumor - derived cells that continuously multiply.

(Mackenzie notes that it shouldn't be a problem for her strategy, because she plans to use the same kind of cells as bone marrow transplants, which haven't caused tumors.)

«In order to block tumor recurrence after radiation therapy, we used an antibody to target and inhibit these cancer stem cells,» said Dr. Xu.

But, counter-intuitively, this mass cell death might be the very thing that makes the animals so long - lived: it could be a natural mechanism their bodies use to clear precancerous cells, stopping tumors in their tracks.

After spending years fighting claims that cell phone use can cause brain tumors, industry reps may be getting some welcome news.