Sentences with phrase «tumor control»

Also known as definitive or full course RT, provides long - term tumor control.
Therefore, it is critical that the initial treatment be focused on pain control as well as tumor control.
In addition, it was determined that repeated treatments in intervals of eight weeks may lead to continuing tumor control.
Thirty - nine percent of the 31 tumors treated with 24 gray of radiation met the criteria for tumor control — a complete or partial response.
Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after SRS, yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial.
Specifically, TheraT ® has proven to be safe in animals as well as capable of eliciting uniquely potent antigen - specific CD8 + cytotoxic T cell responses and strong tumor control in mice.
Jantibody focuses the AMD3100 - invigorated immune response on critical tumor structures, markedly enhancing tumor control.
In 2017, Dr. Kondziolka and colleagues at NYU Langone published a study in the Journal of Neurosurgery demonstrating tumor control rates near 100 percent for brain tumors less than a centimeter in diameter that had been targeted early.
«Less optimal tumor control outcomes among smokers could possibly be explained by the influence of less oxygen concentration within the treated tumors among smokers, which is known to lead to less sensitivity of the cells being killed off by radiation treatments,» Dr. Zelefsky noted.
This study is an update of RTOG 02362, originally published in 20101, and also conducted by the original researchers to evaluate tumor control rates and side effects for patients at five years post-treatment.
Such a positive survival rate is encouraging considering that historically conventional RT resulted in poor tumor control for patients with inoperable lung cancer.
These five - year results demonstrate positive tumor control and disprove the misconception that short - course treatment will result in late - appearing, unacceptable toxicities.»
«Although both anti-CTLA-4 and anti-PD-1 improved tumor rejection, mice treated with anti-CTLA-4 exhibited superior tumor control, suggesting the memory T - cell response by this agent is more durable,» said Allison.
Mice treated just with Bifidobacterium, rather than the full fecal transfer, displayed tumor control comparable to those who received the full mixture.
The decreased tumor size and enhanced tumor rejection in DGKζ - deficient mice indirectly suggests that enhanced Erk signaling may be superior to enhanced NF - κΒ activation in facilitating T cell activity against tumor, especially because DKO mice did not exhibit improved tumor control relative to DGKζ − / − mice.
This integrated team also collaborates to design individualized treatments for each patient, optimizing the patient outcome by maximizing tumor control while minimizing effects on non-tumor tissues.
Six of the 29 initial patients had lasting tumor control, with no detectable evidence of disease 15 months after treatment.
«Canine osteosarcoma treatment focuses on tumor control.
«The initial results of RTOG 0236 showed very good tumor control; however, many physicians were concerned that treatment - related toxicity would eventually appear, so SBRT has not seen wide - spread use.
Patients diagnosed with cancer can now receive electrochemotherapy, significantly reducing the number of treatments needed for local tumor control.
Her current focus is on developing clinical protocols for the treatment of head and neck and lung cancers with a goal of providing enhanced tumor control, including control of metastases, with minimal effect of quality of life.
While digital SCC is typically cured with surgery alone, digital melanomas are typically more aggressive requiring both surgery and systemic therapy to achieve long - term tumor control.
Combining the benefits associated with the bacteria with anti-PD-L1 treatment dramatically improved tumor control.
If hypofractionated radiation with curative intent can reduce the treatment time for lung cancer patients by half with no greater toxicity, and with equivalent — if not better — tumor control and survival outcomes, this research could result in a change in the paradigm of how a large subset of locally advanced NSCLC patients are treated.»
One adaptation to this fortunate reality is that rather than using overall survival (OS) as the measure of a drug's success, many clinical trials now use a kind of midpoint, namely progression - free survival (PFS)-- the time that it takes for a tumor controlled by the trial's medicine to restart its growth.
SBRT appeared to improve tumor control, as suggested by the initial study results for RTOG 0236.
Tumor control could be best achieved with radiation therapy if the tumor is well localized.
Tumor control improved as the radiation dose increased.
Many of the neoplastic diseases we encounter in veterinary practice require a multi-modality approach for successful outcome or even local tumor control.
This allows us to deliver radiation treatments with extreme precision, which results in decreased normal tissue side effects and the ability to increase the radiation dose to the tumor, hopefully improving tumor control.
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