Sentences with phrase «tumor dormancy»
The lab is delineating tumor dormancy in melanoma and characterizing subpopulations of cells with a major focus on slow - proliferating cells that have high proliferation potential hypothesizing that these cells are critical for dormancy and therapy resistance.
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Another major effort of the Herlyn Laboratory is the study of therapy resistance and tumor dormancy.
She continued to develop these models and to investigate the molecular and cellular mechanisms underlying human tumor dormancy as an instructor in Folkman's lab and later as an Assistant Professor at the Center of Cancer Systems Biology at Tufts University School of Medicine, Boston.
The paper is titled «The perivascular niche regulates breast tumor dormancy.»
«In the future, our models should provide robust tools to screen for therapies that impact tumor dormancy and metastasis, and should also provide a platform to solve other biological mysteries that underlie dormancy.»
«The best way to apply immunotherapy as cancer prevention is during tumor dormancy to prevent advanced stage disease.»
Not exact matches
The systemic response to surgery triggers the outgrowth of distant immune - controlled tumors in mouse models of dormancy
His efforts seek to define how tumor cells escape dormancy for growth, invasion, and metastasis, and how to best develop strategies for therapy.
Herlyn's working hypothesis is that defined tumor subpopulations are central to dormancy and drug resistance due to their slow turnover and their non-responsiveness to growth signals.
The working hypothesis of the Herlyn lab is that tumor - maintenance cells (tumor stem cells) are central to dormancy due to their non-proliferation or very slow turnover and their non-responsiveness to growth signals.