Sentences with phrase «tumor formation through»

Loss of this function causes tumor formation through uncontrolled stimulation of AKT, an enzyme that stimulates cell proliferation and survival and is often hyperactive in human tumors.

Not exact matches

We also found that the EphB4 receptor expressed on the surface of breast cancer cells can promote tumor xenograft growth by enhancing blood vessel formation through interactions with its preferred ligand, ephrin - B2, present in tumor endothelial cells.

Carcinogenesis is a multistep process, and oxidative damage is linked to formation of tumors through several mechanisms (9, 10).