Sentences with phrase «tumor growth by»

The University of Kansas is investigating the use of radioactive beads implanted in the tumor, and researchers at other institutions are looking at ways to shut off tumor growth by cutting off the blood supply to the maverick cells.

According to another study on mice, the human equivalent of just two handfuls of walnuts a day cut breast cancer risk in half, and slowed tumor growth by 50 percent as well.

: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply

Cancer: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply [45].

Prechemotherapy short - term fasting has been shown to help reduce tumor growth by supporting chemotherapies» efficacy; evidence also suggests it can lessen chemotherapies» damaging side effects.

If you already have cancer, or if researchers have injected you with highly metastatic melanoma cells, you can buy yourself slightly slower tumor growth by starving yourself of protein.

When they investigated this effect in mice, they found that over eight days progesterone cut tumor growth by 50 percent, without toxicity.

Animal studies indicate that even just.05 % CLA in the diet can inhibit cancerous tumor growth by over fifty percent!

Since 2012, two drugs that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

â $ œTaken together, our results suggest that MBD2 overexpression during gliomagenesis may drive tumor growth by suppressing the anti-angiogenic activity of a key tumor suppressor.

In the study, the compound caused human melanoma cells to die and inhibited tumor growth by about 69 percent in a mouse model.

In tests in mice with a very aggressive form of melanoma, the researchers found they could stop tumor growth by delivering this engineered form of IL - 2, along with antibody drugs, once a week.

Researchers at the University of Mississippi recently found that ethanol — the alcohol in alcoholic drinks — speeds tumor growth by stimulating blood vessel formation.

But recent evidence suggests that Nanog promotes tumor growth by stimulating the proliferation of cancer stem cells.

Suppression of tumor growth by terbinafine is associated with decreased cholesteryl ester concentrations, restoration of PTEN expression, and inhibition of AKT - mTOR, consistent with blockade of SQLE function.

Not exact matches

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

Mogroside V has been found in research to have the ability to inhibit tumor growth in pancreatic cancer by interfering with the rapid dividing of cancer cells, preventing angiogenesis (blood flow to the tumor), and even promoting cancer cell death (10).

Cancer: Flaxseed may protect against breast cancer, prostate cancer, and colon cancer by inhibiting tumor growth and blocking enzymes that are involved in the spread of tumor cells.

In rare cases, anxiety could be triggered by the growth of a tumor that initiates the flight or fight response.

A new study by Dana - Farber Cancer Institute scientists suggests it may be possible to prevent tumors from recurring and to eradicate metastatic growths by implanting a gel containing immunotherapy during surgical removal of a tumor.

Chemotherapy drugs designed to kill tumors may actually encourage ovarian cancer by stimulating the growth of cells that give rise to the malignancy, a new study finds.

The team led by Andreas Plückthun, Director of the Department of Biochemistry at the University of Zurich, involving postdoc Rastik Tamaskovic and PhD student Martin Schwill, has now found out why these antibodies merely slow tumor growth rather than killing off the cancer cells.

Excess expression of the sugar is caused by the same mutation that drives the growth of most DIPG tumors, known as the H3K27M mutation, the team found.

In addition to diminishing the tumor's energy supply, the diet slows the growth of glioblastoma cells by altering a cellular - signaling pathway that commonly occurs in cancers, according to the researchers.

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

The researchers began by investigating a gene called Lgl, which normally suppresses tumor growth.

When the Johns Hopkins scientists saw that their nanoparticle - encapsulated version of BPTES shrunk mice tumors by half, Le and her colleagues searched for what major metabolic pathway was driving the growth of the remaining half of the tumor.

Researchers at the Bellvitge Biomedical Research Institute of Bellvitge, the Catalan Institute of Oncology and the University Hospital of Bellvitge have participated in an international study published in the journal Cancer Cell that describes how exosomes secreted by tumor cells contain protein and microRNA molecules capable of transform neighboring cells into tumoral cells promoting tumor growth.

Now, in a provocative study that raises unsettling questions about the widespread use of vitamin supplements, Swedish researchers have showed that relatively low doses of antioxidants spur the growth of early lung tumors in cancer - prone mice, perhaps by hindering a well - known tumor suppressor gene.

Women with the KRAS - variant are also more susceptible to triple - negative breast cancer, tumors whose growth is not fueled by the hormones estrogen and progesterone, or by the presence of a particular genetic mutation known as HER2, which promotes cancer cell growth.

Called the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS) and funded by the drug giant Novartis, the trial also found fewer cases of lung cancer in those on the treatment, rekindling basic research findings hinting that the same inflammatory pathway may initiate or spur the growth of such tumors.

By contrast, when the team treated the mice with radiation plus a CCL2 - blocking antibody, the tumors» recruitment of monocytes and macrophages was sharply reduced, and the tumor growth was slowed more dramatically.

In this study, we found that chloroquine not only has an effect on the growth of the cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.

«About five percent of people have some kind of cartilage tumor in their bones, and in most cases it's because the growth - plate cartilage cells weren't fully replaced by bone tissue,» Alman said.

However, cancer cells may instead be coaxed to turn back into normal tissue simply by reactivating a single gene, according to a study that found that restoring normal levels of a human colorectal cancer gene in mice stopped tumor growth and re-established normal intestinal function within only 4 days.

«We demonstrated that alpha - KGDH interacts with Gcn5 in the cell nucleus and found that tumor cell proliferation and tumor growth were inhibited when alpha - KGDH was blocked from entering the cell nucleus or by disruption of Gcn5's binding to succinyl - coenzyme A,» said Lu.

Trebananib (formally known as AMG 386; Amgen) is a first - in - class peptide - Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.

In collaboration with the University of Texas Southwestern Medical Center (UTSW) in Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptors.

For several years already, it is well known that tumor growth can be reduced by suppressing autophagy in cancer cells.

Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different orTumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different ortumor spread and growth to different organs.

Isoprenoid - mediated suppression of HMG CoA reductase in tumors was previously correlated to growth arrest; the latter was attenuated by supplemental mevalonate.

Loeb points out that much of the concern over cancer risk is that, as part of standard therapy for advanced prostate cancer, tumor growth is decreased by drugs that drastically reduce rather than increase male hormones.

However, tumor cells can circumvent this immune defense by establishing a surrounding microenvironment that prevents the infiltration of NK cells and thus promotes tumor survival and growth.

The stem cell model says that tumor growth is more hierarchical, mainly driven by a subset of cells that can make new copies of themselves and give rise to the other cell types the tumor contains.

But by combining the drug with a PGAM1 inhibitor to impair both homologous recombination and PARP - dependent DNA repair, the researchers were able to significantly suppress tumor growth.

By blocking these in lung endothelial cells, the researchers were able to slow lung tumor growth in mice and also reduce the spread of metastatic tumors.

One adaptation to this fortunate reality is that rather than using overall survival (OS) as the measure of a drug's success, many clinical trials now use a kind of midpoint, namely progression - free survival (PFS)-- the time that it takes for a tumor controlled by the trial's medicine to restart its growth.

By performing a genome - wide screen in breast cancer cells, Dr. Oesterreich and her colleagues identified a gene called HOXC10 as one that the cancer seems to modify to allow continued tumor growth in patients whose cancer becomes resistant to traditional therapies.

By using molecular genetic tools to reduce the amount of PC in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.