Sentences with phrase «tumor heterogeneity by»

Decipher the molecular basis of cancer & better understand tumor heterogeneity by discovering more variants in a single assay.

Not exact matches

They did so by including factors like the mechanical forces acting on the cells and the tumor's cellular heterogeneity.

For instance, by sequencing single cells from a tumor, the heterogeneity of the cancer can be assessed.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

By means of a non-obese diabetic / severe combined immunodeficiency disease (NOD / SCID) xenotransplant assay in combination with specific cell surface markers (CD44 + CD24 - / low), CSCs were enriched from metastatic and primary breast tumors and were shown to have the ability to reestablish tumor heterogeneity after transplantation [1].

The goal of this center is to bring radiotherapy into the era of personalized medicine by identifying genetic markers of radiotherapy resistance and uncovering how heterogeneity within tumors affects radiotherapy efficacy.

Discover novel treatments in relapsed pediatric cancer by defining tumor heterogeneity and its effect on self - renewal and metastasis.

Demonstrated the prevalence of genetic heterogeneity and branched evolution within a single cancer by sequencing multiple regions from the same tumor