Sentences with phrase «tumor immunity»
Tumor immunity refers to the body's ability to recognize and fight against cancerous tumors. It involves the immune system's response to detect and destroy these abnormal cells to prevent their growth and spread. Full definition
«Blocking this pathway reverses T cell exhaustion and improves tumor immunity in humans and antiviral and anti-tumor responses in animal models,» Wherry notes.
sciencedaily.com
George Coukos and colleagues provide the first data indicating a relationship between tumor immunity and ovarian patient outcomes, reporting that the presence of tumor - infiltrating lymphocytes in the primary tumor strongly correlated with patient survival.
This work, demonstrating that killer T cells mediate naturally occurring human tumor immunity, provided key support for the emerging field of immuno - oncology.
Gain an understanding of how therapeutic interventions targeting dendritic cells can promote tumor immunity and enhance the efficacy of cancer therapy
Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.
The lab also found that apoptotic tumor cells serve as potent instigators of the T cell immune response and has worked on developing cancer vaccines to mimic PND tumor immunity.
Areas of focus include: understanding how tumour - reactive T cells and B cells promote patient survival in cancer; defining the effects of standard treatments on tumor immunity; and using genomic approaches to identify novel tumour mutations that can serve as target antigens for immunotherapy.
In 1997, he became an immunology professor at the Mayo Clinic, Rochester, Minnesota, where he discovered the B7 - H1 (PD - L1) molecule and the role of the B7 - H1 / PD - 1 pathway in the evasion of tumor immunity.
Reference: Nature, «Epigenetic silencing of Th1 type chemokines shapes tumor immunity and immunotherapy,» published online Oct. 26, 2015
The Vaccine & Immunotherapy Center brings together many outstanding researchers within the Institute to focus on new immune based approaches to induce protective tumor immunity, to control the tumor microenvironment, and to use humoral and cellular immunity to control or eliminate cancer.
Research Interests: Tumor immunity, T lymphocyte effectors, immunotherapy, T - cell dysfunction in cancer, myeloid derived suppressor cells (MDSC) and angiogenesis
Pivotal role of the B7: CD28 pathway in transplantation tolerance and tumor immunity.