Sentences with phrase «tumor incidence in»

Moreover, ablation of a STAT5A allele reduces tumor incidence in a mouse model of breast cancer in which mammary epithelial cells express T antigen (48).

Tumor incidences in Fischer 344 rats: NTP historical data.

Not exact matches

Researchers from the University of South Carolina found the incidence of tumors in the colon remained unchanged after weight loss in mouse studies.

Critics of the inclusion of isoflavones in food claim that they increase the incidence of epithelial hyperplasia, which precedes cancerous tumors, and that they cause goitre and hyperthyroidism.

Adjusted relative risk ratios (RRR) and 95 % confidence intervals for the association between prostate cancer incidence and the scores of adherence to Western, Prudent, and Mediterranean dietary patterns in MCC - Spain study by tumor aggressiveness and extension.

«We did not detect any clear change in the long - term time trends in the incidence of brain tumors from 1998 to 2003 in any subgroup,» the researchers wrote in the paper, which was published online Thursday in the Journal of the National Cancer Institute (JNCI).

The study demonstrated a trend toward a reduction in the incidence of tumor recurrence in patients who had pelvic RT..

With an annual incidence of approximately five cases per 100,000 persons, gliomas are the most frequently occurring brain tumor in adults.

We get heavily hyped drugs like Avastin, which shrank tumors without adding significant time to cancer patients» lives (and increased the incidence of heart failure and blood clots to boot); Avandia, which lowered blood sugar in diabetics but raised the average risk of heart attack by 43 percent; torcetrapib, which raised both good cholesterol and death rates; and Flurizan, which reduced brain plaque but failed to slow the cognitive ravages of Alzheimer's disease before trials were finally halted in 2008.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

«Eliminating endothelial CD146 by conditional knockout in two different mouse models of colitis significantly reduced the severity of inflammation and decreased tumor incidence and tumor progression in a mouse model of CAC,» reports lead investigator Xiyun Yan, PhD, from the Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing.

Cancer researchers have found that certain types of dental X-rays significantly increased the incidence of the most common type of brain tumor in the United States: meningioma.

In contrast, because of the high incidence of TP53 mutations in the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such as dasatinib.&raquIn contrast, because of the high incidence of TP53 mutations in the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such as dasatinib.&raquin the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such as dasatinib.»

However, their initial finding demonstrated that progenitor derived from iPSCs generated using lentiviral gene transduction led to the high incidence of highly aggressive tumors in immunodeficient mice after transplantation under the kidney capsule.

But scientists in New Jersey have found that mice who logged plenty of hamster wheel time and ingested lots of caffeine had a 62 percent lower incidence of cancer tumors than those who were lazy and remained uncaffeinated.

Mice have a high incidence of Hodgkin's - like reticulum cell neoplasm at 18 months of age and pituitary tumors in old multiparous females.

P53: The protein p53 plays the role of tumor suppressor, but creating a general increase in p53 levels will, in addition to reducing cancer incidence, also accelerate aging by reducing tissue maintenance through the creation of new cells.

It has a high incidence of spontaneous lung adenomas, and lung tumors readily develop in response to carcinogens.

[26] Vaginal melanomas, with an estimated incidence rate of 0.26 cases per million women per year, account for less than 3 % of vaginal tumors and comprise up to 1 % of all melanomas in women.

An increased latency and reduced incidence in mammary tumors also has been reported in C3H / HeJ and may be related to the Lps mutation (Outzen, H.J., et al., JNCI 75:917, 1985).

So beyond the «regular» high occurrence of benign and malignant tumors in rats, the laboratory strains are probably going to have even higher rates of cancer incidence — they're just not as genetically varied as pet rats who've been allowed to explore OKCupid or, more likely, had a descendant who met a special someone from another alley [source: Ducummon].

Alarmingly, and despite indisputable success achieved in the treatment of these malignancies, their incidence in westernized countries during the last 3 decades has been increasing more rapidly than that of most other tumors.

It is important to note that C188 - 9 did not significantly affect either tumor incidence or latency in virgin mice (p = 0.6 and 0.5, respectively; Figure 6 — figure supplement 4).

«More than 100,000 people in the United States have neuroendocrine tumors, which exceeds the incidence of both pancreatic cancer and stomach cancer in the U.S.»

Mouse studies confirmed the effect of high protein intake and GHR - IGF - 1 signaling on the incidence and progression of breast and melanoma tumors, but also the detrimental effects of a low protein diet in the very old.

Could this explain the greater number of tumors and the disproportionate incidence of breast cancer in the upper outer quadrant of the breast near the armpit?

The incidence of herpes virus type 2 - transformed cell - induced tumors in mice was also reduced in animals fed a fish protein diet.

[I] n 1945 Larsen and Heston found that the incidence of spontaneous pulmonary tumors was doubled in strain A mice fed low - casein diets supplemented with cystine (the most limiting amino acid).

Chemically - induced colon tumor incidence was increased in rats fed the semipurified diets containing 23 % corn oil, safflower oil, lard or beef tallow (high - fat) as compared to those fed 5 % corn oil, safflower oil, lard or beef tallow diets (low - fat).

A study published in Carcinogenesis also found sulforaphane may reduce the incidence and rate of chemically induced mammary tumors in animals.

In the animal study, researchers divided a group of 52 mice with colon cancer tumors into three groups: a control group, a group fed the grape compounds and a group given sulindac, an anti-inflammatory drug that an earlier study showed decreased the incidence of tumors.

Additionally, two randomized, placebo - controlled trials found no significant reduction in the incidence of colon tumor indicators among subjects who supplemented their diet with wheat bran or consumed high fiber diets (MacLennan et al., 1995; McKeown - Eyssen et al., 1994).

MacAllister explains «the higher incidence of nasal tumors for long - nosed breeds probably occurs because these types of breeds have a greater surface area in their noses to be exposed to the carcinogens and for the carcinogens to accumulate.

MacAllister cites a Colorado State University study which found a higher incidence of nasal tumors in dogs living in homes with secondhand smoke compared to those that live in non-smoking homes.

It is beyond the scope of this article to dive into the topics of oral tumors in depth, but it is important to know that healthy teeth decrease their incidence.

The incidence of mammary tumors in cats is statistically similar as dogs, as is the predisposition to tumors increasing with each successive heat cycle.

Anal sac tumors occur in male and female dogs with roughly an equal incidence.

These advantages include decreasing the chances of mammary (breast) tumors later in life, decreasing the chance of cystic ovaries and uterine infections later in life, decreasing the desire to roam the neighborhood, decreasing the incidence of prostate disease later in life, helping prevent spraying and marking, and also decreases the surplus of unwanted puppies and kittens.

These advantages include decreasing the chances of breast tumors later in life, decreasing the chance of cystic ovaries and uterine infections later in life, decreasing the desire to roam the neighborhood, decreasing the incidence of prostate infections later in life, helping prevent spraying and marking, and also decreases the surplus of unwanted puppies and kittens.

In February, 2013, a study of Golden Retrievers, recording the incidence of hip dysplasia (HD), cranial cruciate ligament tears (CCL), lymphosarcoma (LSA), hemangiosarcoma (HAS), and mast cell tumors (MCT) was published.

• A 1998 Colorado State University Study found a higher incidence of nasal tumors and cancer of the sinus in dogs living with smokers compared to dogs living in smoke - free homes.

According to a 2005 study in the Journal of Veterinary Internal Medicine, the incidence of mammary tumors is reduced by 91 percent in cats spayed before six months of age and by 85 percent in cats spayed before one year.

Neutering prevents testicular cancer and greatly reduces the incidence of prostate disease and certain tumors and hernias that are found in the perianal region.

Egenvall A, Bonnett BN, Ohagen P, Olson P, Hedhamar A, et al. (2005) Incidence of, and survival after, mammary tumors in a population of over 80,000 insured female dogs in Sweden from 1995 to 2002.

These advantages include decreasing the chances of mammary tumors later in life, decreasing the chance of cystic ovaries and uterine infections, decreasing the desire to roam the neighborhood, decreasing the incidence of prostate cancer later in life, helping prevent spraying and marking, and also decreasing the surplus of unwanted puppies and kittens that end up in shelters.

These advantages include decreasing the chances of breast tumors later in life, decreasing the chance of cystic ovaries and uterine infections later in life, decreasing the desire to roam the neighborhood, decreasing the incidence of prostate cancer later in life, helping prevent spraying and marking, and also decreases the surplus of unwanted puppies and kittens.

Thyroid irradiation is associated with an increased incidence of thyroid tumors in all species, including humans and dogs.

I find that one interesting and relevant to the original blog post because female dogs studied in Norway had over a 50 % more incidence of mammory tumors.

Vets became much more judicious in their use of the feline leukemia vaccine in an effort to reduce the incidence of injection site tumors.

These advantages include decreasing the chances of breast tumors later in life, decreasing the chance of cystic ovaries and uterine infections later in life, decreasing the desire to roam the neighborhood, decreasing the incidence of prostate cancer later in life, helping prevent spraying and marking, and also decreases the surplus of unwanted kittens.