Instead of targeting specific tumor antigens, this approach relies on endogenous antigens (including neoantigens) released during
tumor lysis by treatments such as chemotherapy or local radiation.
Not exact matches
Recently, we showed that bortezomib treatment in mice bearing breast and kidney
tumors provided host survival benefit
by amplifying
tumor cell caspase8 activation, CD8T cell effector molecules via increased NotchNFkB crosstalk and Fas ligandmediated
lysis of
tumor cells.
Audi spent a couple of days in the hospital on supportive care after starting chemotherapy to help avoid side effects of
tumor lysis, a syndrome that can occur and make the patient very ill when a large volume of
tumor cells are rapidly killed
by chemotherapy.