Sentences with phrase «tumor metastasis identified»

Not exact matches

Looking to target a key pathway in order to interfere with the processes that lead to tumor spread, a research team led by Irwin H. Gelman, Ph.D., of Roswell Park Cancer Institute (RPCI) has identified a new suppressor of cancer metastasis that may point the way toward development of more effective treatments for prostate cancers and other malignant solid tumors.

«How melanoma tumors form: Team identifies drugs that halt skin cancer metastasis in lab tests.»

Cheng and colleagues did experiments using human cells and identified hnRNPM's role in controlling the processes linked to tumor metastasis.

By identifying the cause of this metastasis — which often happens quickly in lung cancer and results in a bleak survival rate — Salk scientists are able to explain why some tumors are more prone to spreading than others.

They showed that the iKnife could distinguish normal and tumor tissues from different organs, such as breast, liver, and brain, and could even identify the origin of a tumor that was a metastasis, a secondary growth seeded by a primary tumor elsewhere in the body.

Pandolfi and colleagues sought to identify an additional tumor suppressing gene or pathway that may work in concert with PTEN to drive metastasis.

Despite this clinical importance, the exact pathologic process of tumor metastasis is as yet poorly understood, and deciphering the exact molecular mechanism of this process is of paramount importance to identify specific therapeutic targets for this devastating disease.

So although genetic sequencing has identified hundreds of genetic alterations linked to tumors, it's still an enormous challenge to figure out which ones are actually responsible for the growth and metastasis of cancer.

Houston Methodist researchers led by Dario Marchetti, PhD, have developed a blood test that can identify circulating tumor cells to predict breast cancer patients at risk for developing brain metastasis.

Researchers at the Université libre de Bruxelles, ULB define for the first time the tumor transition states occurring during cancer progression and identify the tumor cell populations responsible for metastasis.

The idea was to identify genes that were metastasis determinants by correlating gene expression with some kind of invasion assay that measured tumor progression.

The application of subclonal reconstruction methods is providing key insights into tumor evolution, identifying subclonal driver mutations, patterns of parallel evolution and differences in mutational signatures between cellular populations, and characterizing the mechanisms of therapy resistance, spread, and metastasis.

Haihui Lu, Ph.D., a CRI fellow at the Whitehead Institute for Biomedical Research, has identified a surface marker that distinguishes a population of breast cancer cells that are more prone to metastasis and demonstrate higher levels of «stemness,» the ability to seed other tumors.

Roswell Park Cancer Institute researchers have identified a gene that influences metastasis in prostate cancer, and may help clinicians to identify aggressive prostate tumors before they progress and spread to other organs.

There are three grades: Grade I tumors are easily identified and rarely metastasize; Grade II tumors have intermediate differentiation and extend deeper into the underlying tissues and about 20 percent will spread or metastasize; Grade III tumors are poorly differentiated and behave aggressively with an 80 percent or higher chance of metastasis.

It may also help to identify concurrent problems such as bladder stones, changes in appearance of the liver or metastasis from an adrenal tumor.