Sentences with phrase «tumor metastasis when»

Not exact matches

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

When the protein is present, these cells that start out round and stuck together in a pattern resembling cobblestones become irregularly shaped and tend to detach from the tumor site in an uncoordinated way — hallmarks of metastasis.

Cancer metastasis, when tumors spread from their primary location, is almost always deadly, so patients need anti-metastatic therapies.

«We found that many more mice developed tumors when given the cells that we had engineered to have these stem cell characteristics, and they had a much higher incidence of metastasis in the lungs,» Kilian said.

Zhang, who earned an M.D. from the Peking University Health Science Center in China and a Ph.D. from the National University of Singapore, was recruited in 2007 to the Texas team that expected to see an increase of brain metastasis when PTEN, a known tumor - inhibiting protein, was artificially deleted in a tumor cell.

Cell biologist Dr. Jonathan Cooper and his team are working to pinpoint how cells rearrange their inner scaffolding when they travel through the body — cell migration is a key part of both normal development and tumor metastasis.

«We found that sucrose intake in mice comparable to levels of Western diets led to increased tumor growth and metastasis, when compared to a non-sugar starch diet,» said Peiying Yang, Ph.D., assistant professor of Palliative, Rehabilitation, and Integrative Medicine.

Regional lymph node metastasis is uncommon (5 - 10 %) Non-tonsillar SCC is the least likely of the oral tumors to metastasize to the lungs (10 %), and when found in dogs, have the most favorable prognosis when located in the rostral (front) portion of the oral cavity.

A few dogs are diagnosed with advanced metastasis (tumors that have spread to elsewhere in the body, such as the lungs and lymph nodes) and might be feeling ill from their tumors when they come for treatment.