Sentences with phrase «tumor patients so»

The researchers said that in the future, smart fat cells will deliver chemotherapeutic drugs, along with contrast agents, to brain tumor patients so that cancer cells can be detected and wiped out in one step.

Not exact matches

Our partner physicians use data and analytics to do exactly what you described, which is to determine the best protocol for patient care — disease and tumor - specific — so they don't over-treat or waste resources.

For instance, most common adult solid tumors that are not cured by surgical removal are resistant to chemotherapy or radiation control, yet drug therapy is frequently offered as a «possibly effective» treatment because both patient and physician want to believe it so.

Surely, for a patient who can no longer assimilate food, N&H provides no benefit; similarly, some stomach cancer cases result in feeding the tumor instead of the patient; and there are those who are so fragile that almost any invasive insert causes more problems than it relieves.

So or so, yes, not - only - external healing by faith itself of physical things (e.g., bullet in the head, tumor, spear in stomach, viri) seems, respectivly technically is, impossible, but i am pretty sure that about any patient appreciates when a surgeon is focusing at the tasks at hand particularly during operation regardless of statisticSo or so, yes, not - only - external healing by faith itself of physical things (e.g., bullet in the head, tumor, spear in stomach, viri) seems, respectivly technically is, impossible, but i am pretty sure that about any patient appreciates when a surgeon is focusing at the tasks at hand particularly during operation regardless of statisticso, yes, not - only - external healing by faith itself of physical things (e.g., bullet in the head, tumor, spear in stomach, viri) seems, respectivly technically is, impossible, but i am pretty sure that about any patient appreciates when a surgeon is focusing at the tasks at hand particularly during operation regardless of statistics.

So far, researchers with the Allen Institute for Brain Science in Seattle have described the intricate shapes and electrical properties of about 100 nerve cells, or neurons, taken from the brains of 36 patients as they underwent surgery for conditions such as brain tumors or epilepsy.

The Johns Hopkins group and others have shown that so - called liquid biopsies of blood - borne tumor DNA can reveal, for example, whether a patient's cancer should respond to a specific drug.

But all the steps for producing fish avatars, from implanting the tumors to analyzing the results, would take just 2 weeks to 3 weeks, so they could be useful for choosing a patient's initial treatment, she says.

So scientists choose the lymphocytes with the greatest tumor - fighting activity, grow a large population of them in the lab, then infuse them back into the patient.

«We are looking to optimize the combinations of targeted therapies and the scheduling of those therapies so we can improve tumor shrinkage and minimize potential toxicities for a patient,» said Andrew Aplin, PhD, Associate Director for Basic Research and the Program Leader for Cancer Cell Biology and Signaling (CCBS) in the NCI - designated Sidney Kimmel Cancer Center at Jefferson Health.

Biopsied tumor tissue from all 60 new patients was fixed in formalin and embedded in paraffin so that TMEM sites in the tissue could be counted.

A study combining tumor cells from patients with breast cancer with a laboratory model of blood vessel lining provides the most compelling evidence so far that a specific trio of cells is required for the spread of breast cancer.

Importantly, elevated BRCA1 methylation was confined to patients diagnosed with so - called high - grade serous tumors, the most aggressive variant of ovarian cancer, which also is the variant associated with BRCA1 mutations.

«This model supported cancer development so strongly that some mice developed invasive squamous cell skin cancers similar to the patient's tumor,» said lead author Shadmehr Demehri, MD, PhD, a dermatologist and postdoctoral fellow.

In some cases, patients» tumors develop resistance to Gleevec — either the Abl protein mutates so that the drug can no longer bind to it, or the protein accumulates in such quantities that the drug can't keep up, even at the highest dose.

Cancer metastasis, when tumors spread from their primary location, is almost always deadly, so patients need anti-metastatic therapies.

The underlying basis of cancer immunotherapy is to activate a patient's own T cells so that they can kill their tumors.

However, many tumor proteins do not provoke T cells to attack, so T cells must be removed from the patient and programmed to attack a specific tumor molecule.

«Our discovery of germline mutations in so many cases of Wilms tumor means that the children and family members of these patients may be at risk for tumor development,» said Perlman.

To investigate why checkpoint inhibitors so often stop working, Velculescu; Valsamo Anagnostou, M.D., Ph.D., instructor of oncology at the Johns Hopkins University School of Medicine; Kellie N. Smith, Ph.D., a cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-CTLA4.

Or stem cells injected into a patient as therapy might be designed so that their tumor suppressor genes are less likely to mutate and cause cancer.

The side - effects of these treatments can be significant, so current research is focused around precision medicine — classifying patients on their tumor's molecular changes, and only giving them the treatments that are expected to be most effective.

The prognosis for metastatic cancer (also called stage IV cancer) is generally poor, so a technique that could detect these circulating tumor cells before they have a chance to form new colonies of tumors at distant sites could greatly increase a patient's survival odds.

So for 17 patients with advanced melanoma who didn't have tumor - fighting T cells and had failed existing treatments, Rosenberg's team tried gene therapy.

One idea the team is mulling is to implant in patients a bag of iPS - derived liver cells that are self - contained, so they can't seed tumors in a patient's tissues but can still produce A1ATD.

But so far in trials for ovarian cancer they have blocked tumor growth in many patients, Levine notes.

Half to 90 percent of glioblastoma cells use this cellular process so indoximod helps a patient's own immune system to find and attack their tumors.

So my field is science and technology, so my work is circulating tumor cells where I isolate cancer cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapSo my field is science and technology, so my work is circulating tumor cells where I isolate cancer cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapso my work is circulating tumor cells where I isolate cancer cells from blood of patients and isolate their DNA and RNA and try to sequence them and try to device treatments for cancer treatment and therapy.

The test, called ProsignaTM and manufactured by NanoString Technologies, comes with a machine and kit, so patients» tumor samples do not have to be sent to a single laboratory for analysis.

It can also do this by dividing and making more T cells so that these engineered T cells are capable of eradicating literally pounds of tumors in patients.

The fusion of these two genes was observed in just three percent of tumors studied, so any therapy based on this particular genetic aberration would apply to only a small subset of glioblastoma patients.

About 1,000 patients whose tumor characteristics most closely match one of the 20 or so gene - targeting drugs offered in the study will be put into groups of about 30 patients to get that drug.

The researchers discovered a single letter variant located in TP53, a gene known to play a central role in tumor biology and for accumulating so called somatic mutations, during the development of cancer in patients.

Importantly, however, survival was equivalent in the two arms of the nivolumab study, with less serious toxicity than in the chemotherapy arm, so it also represents a reasonable option for patients with lower PD - L1 expression in their tumors.

Sedation is often used to help patients stay in the exact position needed so radiation hits the tumor and not nearby healthy tissue.

«We're hopeful that genetic analysis of GATOR1 in tumors could help predict which cancer patients would respond to rapamycin, so there would be a clinical benefit to measuring these mutations,» says Whitehead Member David Sabatini.

«Each patient is different, so we're developing a personalized vaccine based on specific targets we identify on a patient's tumor,» Overman says.

Every three months or so, the patient will return to get the tumor scanned again, and the drug regimen will be altered according to what mutations are now present.

Only five of the 29 patients treated so far, however, had tumor progression in more than five sites.

«Tamoxifen is an excellent agent to use to both prevent breast cancer in high - risk women, and to reduce cancer recurrence in women who develop tumors, so our goal is to ensure that patients who use this drug can respond to it,» Hilakivi - Clarke says.

The specific antigen approach uses selected antigens that are also present in the patient's tumor so that the immune system will be educated to recognize the tumor antigen and kill tumor cells expressing the antigen.

The mission of our lab is to improve therapy for patients with brain tumors by elucidating the molecular mechanisms driving cancer initiation and progression, and in doing so, promote rigorous science and train the next generation of scientists.

White blood cells that fight infection are removed from the patient, modified so they target the tumor specifically, and are re-introduced into the body where they encourage other cells also to attack the malignant cells.

According to the National Cancer Institute, radiation therapy helps shrink tumors so the pressure and the pain resulting from that pressure are relieved in the patient.

The most common uses of local anesthetics in the rabbit include minor skin procedures (skin biopsies, small tumor removals, IV catheter placement), ophthalmic procedures (tear duct flushing and thorough eye exam) and nasoesophageal tube placement (the drops are put in the nose so the small tube can be placed in the awake patient without discomfort).

I give a patient chemotherapy an the tumor volume shrinks by 10 %, but I know the doubling time is 4 weeks, so after 3 and a half months I can claim I have killed 100 % of the tumor.

The biggest thing is making sure you can qualify for life insurance with SBLI, so lets cover (in general) what SBLI will and won't insure: SBLI Underwriting Uninsurable medical scenarios with SBLI: • Aids / HIV + status • ALS (Amyotrophic Lateral Sclerosis) • Alzheimer's disease or dementia or significant cognitive impairments related to functionality • Cancer diagnosis within last 2 years • Chronic pain treatment, severe, receiving disability, narcotic use • Cirrhosis of the Liver • Congestive heart Failure • COPD / Emphysema or chronic bronchitis - Severe or with current nicotine use • Cystic Fibrosis • Defibrillator use • Depression, severe, recurrent or with multiple in - patient hospitalization history • Diabetes with co-morbidities that include significant cardiac disease, or impairment of renal function or mobility • Heart / Cardiac Disease - multiple vessels diagnosed within 2 years or any past history with current nicotine use • Muscular Dystrophy • Multiple Sclerosis, if symptoms progressing • Organ Transplants, in most scenarios • Quadriplegia • Pulmonary hypertension • Renal failure, Renal insufficiency - severe • Stroke within 1 year • Suicide attempt within 5 years • Surgical repair of heart valves, aneurysms, intracranial tumors, major organs within six months, including gastric bypass Uninsurable non-medical scenarios: • Marijuana use, 4 or more times weekly • Substance abuse / misuse within last 5 years • Criminal activity - any history within the last 10 years • DUI, more than 2 or under age 25 if within 1 year • Unemployed (other than homemakers or retired) with minimal household income or dependent on SSI / disability benefits • Bankruptcy filing within 2 years • Liens / Judgements - outstanding activity that exceeds $ 50K