Sentences with phrase «tumor patients without»

His laboratory at the German Cancer Research Center in Heidelberg and at the Medical Faculty Mannheim of Heidelberg University is studying the mechanisms of metastasis with the goal to develop more gentle supportive adjuvant therapies for tumor patients without detectable metastases following surgery of the primary tumor.

Not exact matches

We get heavily hyped drugs like Avastin, which shrank tumors without adding significant time to cancer patients» lives (and increased the incidence of heart failure and blood clots to boot); Avandia, which lowered blood sugar in diabetics but raised the average risk of heart attack by 43 percent; torcetrapib, which raised both good cholesterol and death rates; and Flurizan, which reduced brain plaque but failed to slow the cognitive ravages of Alzheimer's disease before trials were finally halted in 2008.

The study's conclusions address a major challenge in current standards of care for prostate cancer: Without knowing a tumor's underlying biology, physicians can not reliably predict which of their patients will develop dangerous forms of the disease.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

A newly devised tumor - specific fluorescent agent and imaging system guided surgeons in real time to remove additional tumors in ovarian cancer patients that were not visible without fluorescence or could not be felt during surgery, reports Alexander L. Vahrmeijer MD, PhD, head of the Image - guided Surgery group in the Department of Surgery at Leiden University Medical Center in the Netherlands.

Researchers from Massachusetts Eye and Ear / Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro)-- similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

Cancer patients without overt metastases appear to be «tumor - free» upon surgical removal of the primary tumor.

A few years ago Peperstraete stumbled on an article in a science journal about medical researchers using crossed laser beams to image and heat tumors in a patient without disturbing any of the surrounding tissue.

CRC is the second - leading cause of cancer - related deaths in the United States, and about 70 percent of CRC patients in this study have tumors without mutations in the KRAS gene.

Researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford have developed a way to scan young cancer patients» bodies for tumors without exposing them to radiation.

They divided 48 patients into two groups, those with and without these mutations in their tumors.

The study further suggests that NSAIDs such as aspirin, ibuprofen and naproxen have a particularly advantageous effect when taken after diagnosis by colorectal, or CRC, patients without tumor mutation in the KRAS gene (KRAS wild - type tumors): The study shows that NSAID use by this group is associated with a survival benefit of 40 percent.

In their search for novel, tumor - specific therapies that could target multiple brain metastases without damaging adjacent tissues, the research team first developed a mouse model that more closely mimics what is seen in patients.

To further validate our result in clinical samples, we obtained primary tumor from patients with advanced breast cancer and the tissue was passaged once in nonobese diabetic / severe combined immunodeficient mouse without in vitro culture.

In similar patients enrolled in a previous national trial, tumor size decreased in only 40 percent of patients treated with the same drugs but without hu14.18 K322A.

Pramod Srivastava, Giorgio Parmiani, and colleagues report that immunization with autologous tumor - derived gp96 - peptide complexes elicits tumor regression in stage IV melanoma patients, without any immunization - related adverse events.

Just as one can't truly identify somatic mutations in a tumor tissue without a matched normal, it's nearly impossible to distinguish de novo mutations in a patient without sequencing both of his or her parents.

The researchers tested whether stromal tumor infiltrating lymphocytes (TILs) and other immune cells might predict responses to therapy in a set of 30 HER2 - positive breast cancer tissues treated with TCHP (26 patients) or with TCH without pertuzumab (4 patients).

Three groups of volunteers were recruited: 10 colon cancer patients whose tumors had the genetic problem; 18 colon cancer patients without it; and 7 patients with other malignancies with the defect.

(F) Immunohistochemical assay of p - ERK in tumor samples of PTCL - NOS patients with or without KMT2D mutations.

In tumor samples from PTCL - NOS patients, a significantly lower fraction of nuclear H3K4me3 positivity (+ + + ~ + + + +, 30 %) was observed in cases with the KMT2D mutation than in those without mutations.

(D) Immunostaining of H3K4me3 and H3K18ac in tumor samples of PTCL - NOS patients with or without KMT2D or EP300 mutations.

Patients were often put through grueling — and expensive — treatment protocols without knowing how their tumors would react.

Analysis of these tumors confirmed observations that patients with mutated BRCA1 and BRCA2 genes have better survival odds than patients without mutations in these genes.

Researchers say that patients whose tumors have high levels of PD - L1, a protein linked to increased risk of the disease, had longer survival to chemotherapy without progression of the disease.

Hi I happen to be a cancer patient and can not go to school but was wondering if I could take a course to teach me more about cats and their medical problems I volunteered with a cat rescue for twelve years and still do but still do nt have all the answers for example one of my own cats just past away because of a tumor in the abdomen and it took the vets down here close to three months before they could figure out what the problem was and by that time it was too late to save her please let me know if I can take this course by correspondence online without having to go to school and how much would it cost in monthly payments thanks

The most common uses of local anesthetics in the rabbit include minor skin procedures (skin biopsies, small tumor removals, IV catheter placement), ophthalmic procedures (tear duct flushing and thorough eye exam) and nasoesophageal tube placement (the drops are put in the nose so the small tube can be placed in the awake patient without discomfort).