Sentences with phrase «tumor proteins»

However, many tumor proteins do not provoke T cells to attack, so T cells must be removed from the patient and programmed to attack a specific tumor molecule.

The technology, developed by MIT professor and Howard Hughes Medical Institute investigator Sangeeta Bhatia, relies on nanoparticles that interact with tumor proteins called proteases, each of which can trigger release of hundreds of biomarkers that are then easily detectable in a patient's urine.

In different contexts, viruses appear capable of attacking tumors in a number of different ways — by directly infecting them, by releasing tumor proteins that trigger a broad immune response against the cancer, and by damaging the blood supply tumors need to survive.

«Rogue breast tumor proteins point to potential drug therapies: Such treatment options are missed by genomic sequencing.»

There is also a test called the Bladder Tumor Antigen Test (BTA) which looks for tumor proteins in the urine.

In 2012, Bhatia and colleagues introduced the concept of a synthetic biomarker technology to amplify signals from tumor proteins that would be hard to detect on their own.

In recent tests, genetically engineered yeast in the vaccine delivered a common tumor protein that stimulated the immune systems of mice, thereby destroying tumors.

p53 (aka tumor protein 53) is a transcription factor whose inactivation can trigger the onset of cancer.

The researchers found that by killing some tumor cells directly, the viral infection exposed tumor proteins that could be detected by the immune system, triggering an immune attack on the rest of the tumor.

Utilizing advanced proteomics technology, Provista Diagnostics has developed Videssa Breast, a simple blood test that detects and analyzes multiple tumor protein biomarkers for improved breast cancer detection.

Unlike other blood - based technologies, such as, circulating tumor cells and cell - free DNA, breast cancer tumor proteins are well understood in the scientific literature and readily identified in the blood, offering a more effective approach to cancer detection.

Tumor protein p53 is one of the most critical determinants of the fate of cancer cells, as it can determine whether a cell lives or dies in response to stress.

The new test makes use of a «synthetic biomarker» — a nanoparticle that interacts with tumor proteins to release fragments that can be detected in a patient's urine sample.

The test detects a combination of five tumor proteins that appear to be a reliable signature of the disease, the researchers report in the May 24...

«If a protein is only highly edited in the tumor proteins, but not in normal proteins, then it's possible that a specific drug could be designed to inhibit the edited mutant protein,» said Liang.

Once inside, these immune cells came in contact with the tumor proteins and learned to recognize them as well.

They also showed that drugs against a type of breast tumor called HER2 positive breast cancer — such as the dual ERBB2 / EGFR inhibitor lapatinib — potentially could benefit more patients than currently receive them, if analysis of the tumor proteins is taken into consideration.

When the researchers examined the tumors, they discovered that the second drug acted by making the immune system hyper - alert to tumor proteins released by the viral infection, rather than through effects on tumor blood vessels.

Once these nanoparticles are taken up by immune cells, the tumor proteins attached to their surface can help immune cells recognize identify cancer cells across body.

We will use a vaccine made from the bacteria Listeria monocytogenes, which has been genetically modified to express a tumor protein (HER - 2 / neu) that is found in many cancer cells, including canine bone cancer cells and cancer stem cells.