Sentences with phrase «tumor recurrence»

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

Also, no evidence of local tumor recurrence.

«Low - dose chemotherapy regimens could prevent tumor recurrence in types of breast cancer, pancreatic cancer.»

«In order to block tumor recurrence after radiation therapy, we used an antibody to target and inhibit these cancer stem cells,» said Dr. Xu.

The ability for cancer cells to develop resistance to chemotherapy drugs — known as multi-drug resistance — remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to «turn off» their resistance capabilities.

The study demonstrated a trend toward a reduction in the incidence of tumor recurrence in patients who had pelvic RT..

They are associated with tumor recurrence and metastasis, the lethal spreading of cancer to other organs.

By using the blue light technique, the rates of bladder tumor recurrence are lower, allowing patients to avoid invasive procedures and potentially reduce the frequency of their bladder checks.

The study, which will not be completed for at least five years, will evaluate whether the vaccine prevents tumor recurrence rather than causing shrinkage.

A blood test for CA - 125, a protein that is elevated in some women with ovarian cancer, is frequently used to monitor tumor recurrence, but the test lacks sufficient accuracy for screening purposes.

«Studies like the current one involving rhabdomyosarcoma are giving us a close - up look at the way cancer evolves in response to treatment,» said study co-author Richard K. Wilson, Ph.D., director of The Genome Institute at Washington University School of Medicine in St. Louis, where scientists have extensive expertise analyzing tumor recurrence using whole - genome sequencing.

CSCs are thought to drive tumor recurrence, progression, metastasis and drug resistance.

The primary endpoint of this trial is recurrence of breast cancer in the same breast, known as ipsilateral breast tumor recurrence (IBTR).

Slightly more than 10 % of all patients who undergo successful surgery for prostate cancer have an elevated risk of tumor recurrence afterwards — especially as metastases.

Aside from tumor recurrence, he could also be dealing with organ rejection or a possible hormone imbalance if the tumor is active.

However, it may be possible to prevent resistance and tumor recurrence by targeting both mitochondrial metabolism and FGFR3 - TACC3 directly.»

Not only did the gene's activation seem to underlie newly diagnosed tumors, but it was also an important driver of tumor recurrence following treatment.

While post-transplant tumor recurrence has decreased over the years, it is still of concern, as it typically leads to patient demise.

This study is to evaluate use of everolimus and tacrolimus in a prospective manner to see if the use of these two medications results in lower tumor recurrence and better patient survival than tacrolimus and mycophenolic acid / mycophenolate mofetil after liver transplantation for HCC.

However, it can be difficult to distinguish between tumor recurrence that needs further treatment and harmless treatment - associated scar tissue that requires no further action.

If the implant proves to prevent mammary tumor recurrence and you would like your rat to be implanted with another deslorelin implant in a year, the cost of this implant will be at your charge.

If the mammary tumor is malignant, the surgical site and regional lymph nodes should be checked for local tumor recurrence and metastasis, respectively, every 3 months for the first 12 months after surgery and then every 6 months thereafter.

The ability for cancer cells to develop resistance to chemotherapy drugs - known as multi-drug resistance - remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists...

tumors from neural stem cells also contained more glioblastoma stem cells, cells that are believed to give rise to tumor recurrence after therapy,» says Lene Uhrbom, senior lecturer at the Department of Immunology, Genetics and Pathology and lead author of the study.

A recent study of the old white light technique versus the newer blue light technique found the average time to a bladder tumor recurrence was seven months longer with the blue light.

The researchers note that persistent absence of normal B cells following CTL019 treatment indicates continued activity of the gene - modified T cells, which are thought to provide long - term, vaccine - like activity preventing tumor recurrence.

Estrogens stimulate the growth of breast tissue, so in theory, the high estrogen levels associated with pregnancy could raise the risk of tumor recurrence or death in women who have had breast cancer.

Currently, rising blood levels of prostate - specific antigen (PSA), a protein made by the prostate gland, are used as indicators of tumor recurrence.

The trial was designed to evaluate overall survival statistics and progression - free survival — the period of time between initial treatment and tumor recurrence.

The most significant predictors of mortality were tumor recurrence and less aggressive (non-enbloc) tumor resection.

Complete removal of all cancerous cells is crucial, as any residual cells can cause tumor recurrence.

In their paper published online in the Journal of Clinical Oncology, the researchers report that several genetic characteristics of more aggressive tumors were significantly more prevalent in African American patients and appeared to be associated with a greater risk of tumor recurrence.

Tumor recurrence was faster and more likely among African American patients, particularly for basal subtype tumors or those driven by the TP53 mutation.

«The higher risk of tumor recurrence that we observed among African American women was reduced when controlling for those factors, suggesting that these genomic differences contribute, at least partly, to the known racial disparity in the survival of African American and Caucasian breast cancer patients.»

Each chart was reviewed for patient demographics, presenting symptoms and signs, tumor location and size, imaging findings, extent of surgical resection, histopathological findings, radiographic follow - up, tumor recurrence, and clinical outcome.

Kancera combines industrial and clinical experience with frontline research to target the mechanisms of tumor recurrence and develop candidate drugs for new molecular targets.

Dr. Giannoula Klement, an internationally recognized expert on tumor angiogenesis and antiangiogenic therapy, worked with Judah Folkman elucidating the role of platelets in angiogenesis and their possible role as biomarkers in the early detection of cancer and tumor recurrence.

Therefore, all attempts should be made to decrease the likelihood of tumor recurrence.

If the infiltrated cells are in fact differentiated tumor cells, their dissemination beyond the surgical boundary may not be the primary cause of tumor recurrence.

This tumor recurrence often shows up in different sites such bones, lung, liver, or brain and primarily responsible for breast cancer related deaths.

Slow down lymphoma growth modestly and show no effect on tumor regression; delay tumor recurrence with activation of p53; enhance tumor regression and inhibit tumor recurrence after alkylating drug therapy.

Local tumor recurrence or tumor progression can be delayed by months to years with CFRT, and a local cure may be obtained in many instances.

Even with aggressive surgery, the tumor recurrence rate is very high (at least 50 % by 6 months after surgery).

«Some dogs can not tolerate amputation, and current limb - sparing surgery, where the affected bone is replaced with a substitute bone or a metal limbspare implant, may involve complications such as implant failure, infection, fracture, allograft resorption (weakening the bone) or local tumor recurrence,» says Dr. Denis Marcellin - Little, professor of orthopedics who is conducting the study.

Even with treatment, no therapy for SCC is 100 percent effective and tumor recurrence is high, with approximately one in five horses experiencing cancer relapse.

When complete removal of the tumor is not possible with the partial ulnectomy, radiation therapy may be beneficial to prevent local tumor recurrence.

The complications that might arise after limb - sparing surgery could be implant failure, local tumor recurrence, and infection.