Sentences with phrase «tumor response»

In addition, he applies 3 - D techniques to aid in the detection and staging of pancreatic cancer, and in the evaluation of tumor response to chemotherapy.

Even more nerve - racking for the patients was the fact that typically six weeks would pass before he could assess tumor response.

MCG / AU Health was the only site for the phase 1 trial to test the vaccine's safety and look at tumor response in patients with persistent, recurrent and / or metastatic disease.

Of even more interest, dogs receiving vinblastine and piroxicam together had the following tumor responses: 58 % partial remission, 33 % stable disease, and 8 % progressive disease with a median survival of 299 days (range 21 - 637 days).

«A second interim tumor response / immunological response update is expected later in FY Q4 / 17,» Loe indicated.

Though the study was small, the results were promising: blocking CCR2 led to a much better tumor response compared to chemo alone.

To more directly assess the role of GSTO1 and RYR1 in the breast tumor response to chemotherapy, the researchers injected human breast cancer cells into the mammary gland of mice and then treated the mice with carboplatin after tumors had formed.

Partnering with the U.S. Food and Drug Administration allowed Doebele and colleagues to access clinical trial data describing initial tumor response, PFS and OS for 305 patients with stage IIIb or IV non-small cell lung cancer on trials of ALK inhibitors and 355 similar patients on trials of immunotherapies directed at PD - 1.

If these results are confirmed in live mouse studies, they could eventually lead to new strategies to predict tumor response to anti-angiogenic therapy in people.

While lack of PARP - 1 confers high resistance to PARPis, it has not been established whether or not the levels of PARP - 1 directly correlate with tumor response.

If researchers can use the mice to gather information about specific tumor responses to specific drugs, then they can bank that information to be used in the general population.

Using in vitro cell culture and an in vivo colorectal cancer mouse xenograft models, the laboratory is studying novel therapy combinations and interventions to help increase tumor response to treatment.

[31] Animal brain metastasis models have demonstrated significant tumor response and improved survival with this compound.

Prostate tumors can have a wide array of mutations in these genes — but how these various mutations may affect tumor responses to different PI3K - targeted drugs is unknown.

Her background in molecular biology, cell biology, and tumor biology, as well as publications of her research, has prepared Dr. Vines to study the regulation of CCR7 - mediated tumor responses in selected murine models.

Research techniques — unique to the Kimmel Cancer Center — allow us to study the effects of radiation therapy in ways never before possible and to image, quantify and measure tumor responses in real time.

Induction of immune responses in patients with b - cell lymphoma against the surface - immunoglobulin idiotype expressed by their tumors

According to the head of the research group of chemoresistance and Predictors of tumor response and stromal environment ICO - IDIBELL, Alberto Villanueva, «tumor exosomes contain certain proteins (Dicer, TRBP and Ago2) able to process microRNAs that can alter the around the tumor cells transforming them into tumoral cells.»

Each factor involved in the tumor response — whether it is the speed with which chemotherapeutic drugs reach the tissue or the degree to which cells signal each other to grow — is characterized by a mathematical equation that captures its essence.

Combining Paclitaxel with Nutlin - 3 not only potentiated the tumor response to Paclitaxel, but also prevented Numb - deficient tumors from re-growing after treatment discontinuation.

Tumor responses were seen in 25 percent of patients overall, including eight patients with complete responses and 12 with partial responses.

In Vivo Imaging of Tumor Response to Therapy Using a Dual - Modality Imaging Strategy.

In nonmetastatic triple - negative breast cancer (TNBC) patients, we investigated whether circulating tumor DNA (ctDNA) detection can reflect the tumor response to neoadjuvant chemotherapy (NCT) and detect minimal residual disease after surgery.

With a focus on high - tech radiotherapy such as image guided radiotherapy (IGRT), stereotactic body radiotherapy (SBRT), brachytherapy and radiobiologic modulation of tumor response, I have had the chance to use precise radiotherapy to treat variety of tumor sites such as genitourinary, gynecologic, soft tissue sarcoma, gastrointestinal, head and neck cancer and metastatic disease.

Tumor responses were observed in injected lesions, in noninjected cutaneous lesions, and in noninjected visceral lesions.

In a recent randomized trial, dogs treated with vinblastine alone had the following tumor responses: 22 % partial remission, 70 % stable disease, and 4 % progressive disease, and 4 % were not evaluable for tumor response.

The study included 13 cats, and the treatment had a 55 percent response rate (including both cats that had complete tumor response or partial tumor response).